183 related articles for article (PubMed ID: 23940660)
1. Akt-induced phosphorylation of N-CoR at serine 1450 contributes to its misfolded conformational dependent loss (MCDL) in acute myeloid leukemia of the M5 subtype.
Nin DS; Ali AB; Okumura K; Asou N; Chen CS; Chng WJ; Khan M
PLoS One; 2013; 8(8):e70891. PubMed ID: 23940660
[TBL] [Abstract][Full Text] [Related]
2. Role of misfolded N-CoR mediated transcriptional deregulation of Flt3 in acute monocytic leukemia (AML)-M5 subtype.
Nin DS; Kok WK; Li F; Takahashi S; Chng WJ; Khan M
PLoS One; 2012; 7(4):e34501. PubMed ID: 22514634
[TBL] [Abstract][Full Text] [Related]
3. Misfolded N-CoR is Linked to the Ectopic Reactivation of CD34/Flt3-Based Stem-Cell Phenotype in Promyelocytic and Monocytic Acute Myeloid Leukemia.
Nin DS; Li F; Visvanathan S; Khan M
Front Oncol; 2015; 5():210. PubMed ID: 26500885
[TBL] [Abstract][Full Text] [Related]
4. Role of chaperone mediated autophagy (CMA) in the degradation of misfolded N-CoR protein in non-small cell lung cancer (NSCLC) cells.
Ali AB; Nin DS; Tam J; Khan M
PLoS One; 2011; 6(9):e25268. PubMed ID: 21966475
[TBL] [Abstract][Full Text] [Related]
5. Autophagic Degradation of Misfolded Nuclear Receptor Co-repressor (NCoR) Is Linked to the Growth of Tumor Cells in HBX Positive Hepatocellular Carcinoma (HCC).
Tan SY; Visvanathan S; Abu Hassan R; Khan M
Front Oncol; 2019; 9():1335. PubMed ID: 31850220
[TBL] [Abstract][Full Text] [Related]
6. Curcumin sensitizes acute promyelocytic leukemia cells to unfolded protein response-induced apoptosis by blocking the loss of misfolded N-CoR protein.
Ng AP; Chng WJ; Khan M
Mol Cancer Res; 2011 Jul; 9(7):878-88. PubMed ID: 21602299
[TBL] [Abstract][Full Text] [Related]
7. Interplay of protein misfolding pathway and unfolded-protein response in acute promyelocytic leukemia.
Khan M
Expert Rev Proteomics; 2010 Aug; 7(4):591-600. PubMed ID: 20653512
[TBL] [Abstract][Full Text] [Related]
8. The effect of a PP2A inhibitor on the nuclear receptor corepressor pathway in glioma.
Lu J; Zhuang Z; Song DK; Mehta GU; Ikejiri B; Mushlin H; Park DM; Lonser RR
J Neurosurg; 2010 Aug; 113(2):225-33. PubMed ID: 20001590
[TBL] [Abstract][Full Text] [Related]
9. Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.
Brandts CH; Sargin B; Rode M; Biermann C; Lindtner B; Schwäble J; Buerger H; Müller-Tidow C; Choudhary C; McMahon M; Berdel WE; Serve H
Cancer Res; 2005 Nov; 65(21):9643-50. PubMed ID: 16266983
[TBL] [Abstract][Full Text] [Related]
10. Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.
Ng AP; Nin DS; Fong JH; Venkataraman D; Chen CS; Khan M
Mol Cancer Ther; 2007 Aug; 6(8):2240-8. PubMed ID: 17699721
[TBL] [Abstract][Full Text] [Related]
11. Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells.
Spiekermann K; Bagrintseva K; Schwab R; Schmieja K; Hiddemann W
Clin Cancer Res; 2003 Jun; 9(6):2140-50. PubMed ID: 12796379
[TBL] [Abstract][Full Text] [Related]
12. Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells.
Trombly DJ; Whitfield TW; Padmanabhan S; Gordon JA; Lian JB; van Wijnen AJ; Zaidi SK; Stein JL; Stein GS
BMC Genomics; 2015 Apr; 16(1):309. PubMed ID: 25928846
[TBL] [Abstract][Full Text] [Related]
13. FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.
Kazi JU; Rönnstrand L
Mol Oncol; 2013 Jun; 7(3):402-18. PubMed ID: 23246379
[TBL] [Abstract][Full Text] [Related]
14. RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.
Schwäble J; Choudhary C; Thiede C; Tickenbrock L; Sargin B; Steur C; Rehage M; Rudat A; Brandts C; Berdel WE; Müller-Tidow C; Serve H
Blood; 2005 Mar; 105(5):2107-14. PubMed ID: 15536149
[TBL] [Abstract][Full Text] [Related]
15. Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia.
Zeng Z; Samudio IJ; Zhang W; Estrov Z; Pelicano H; Harris D; Frolova O; Hail N; Chen W; Kornblau SM; Huang P; Lu Y; Mills GB; Andreeff M; Konopleva M
Cancer Res; 2006 Apr; 66(7):3737-46. PubMed ID: 16585200
[TBL] [Abstract][Full Text] [Related]
16. N-CoR controls differentiation of neural stem cells into astrocytes.
Hermanson O; Jepsen K; Rosenfeld MG
Nature; 2002 Oct; 419(6910):934-9. PubMed ID: 12410313
[TBL] [Abstract][Full Text] [Related]
17. Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.
Tazzari PL; Cappellini A; Ricci F; Evangelisti C; Papa V; Grafone T; Martinelli G; Conte R; Cocco L; McCubrey JA; Martelli AM
Leukemia; 2007 Mar; 21(3):427-38. PubMed ID: 17215852
[TBL] [Abstract][Full Text] [Related]
18. The E3 ubiquitin ligase TRAF6 inhibits LPS-induced AKT activation in FLT3-ITD-positive MV4-11 AML cells.
Schnetzke U; Fischer M; Kuhn AK; Spies-Weisshart B; Zirm E; Hochhaus A; Müller JP; Scholl S
J Cancer Res Clin Oncol; 2013 Apr; 139(4):605-15. PubMed ID: 23263202
[TBL] [Abstract][Full Text] [Related]
19. Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry.
Tazzari PL; Cappellini A; Grafone T; Mantovani I; Ricci F; Billi AM; Ottaviani E; Conte R; Martinelli G; Martelli AM
Br J Haematol; 2004 Sep; 126(5):675-81. PubMed ID: 15327518
[TBL] [Abstract][Full Text] [Related]
20. FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia.
Nogami A; Oshikawa G; Okada K; Fukutake S; Umezawa Y; Nagao T; Kurosu T; Miura O
Oncotarget; 2015 Apr; 6(11):9189-205. PubMed ID: 25826077
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]