BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 25239454)

  • 1. TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors.
    Condelli V; Piscazzi A; Sisinni L; Matassa DS; Maddalena F; Lettini G; Simeon V; Palladino G; Amoroso MR; Trino S; Esposito F; Landriscina M
    Cancer Res; 2014 Nov; 74(22):6693-704. PubMed ID: 25239454
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma.
    Condelli V; Maddalena F; Sisinni L; Lettini G; Matassa DS; Piscazzi A; Palladino G; Amoroso MR; Esposito F; Landriscina M
    Oncotarget; 2015 Sep; 6(26):22298-309. PubMed ID: 26084290
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TRAP1 controls cell cycle G2-M transition through the regulation of CDK1 and MAD2 expression/ubiquitination.
    Sisinni L; Maddalena F; Condelli V; Pannone G; Simeon V; Li Bergolis V; Lopes E; Piscazzi A; Matassa DS; Mazzoccoli C; Nozza F; Lettini G; Amoroso MR; Bufo P; Esposito F; Landriscina M
    J Pathol; 2017 Sep; 243(1):123-134. PubMed ID: 28678347
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRAP1 regulates cell cycle and apoptosis in thyroid carcinoma cells.
    Palladino G; Notarangelo T; Pannone G; Piscazzi A; Lamacchia O; Sisinni L; Spagnoletti G; Toti P; Santoro A; Storto G; Bufo P; Cignarelli M; Esposito F; Landriscina M
    Endocr Relat Cancer; 2016 Sep; 23(9):699-709. PubMed ID: 27422900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma.
    Lettini G; Sisinni L; Condelli V; Matassa DS; Simeon V; Maddalena F; Gemei M; Lopes E; Vita G; Del Vecchio L; Esposito F; Landriscina M
    Cell Death Differ; 2016 Nov; 23(11):1792-1803. PubMed ID: 27662365
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.
    Wang CY; Guo ST; Wang JY; Yan XG; Farrelly M; Zhang YY; Liu F; Yari H; La T; Lei FX; Jin L; Zhang XD; Jiang CC
    Oncotarget; 2016 Aug; 7(31):49597-49610. PubMed ID: 27391062
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
    Preto A; Figueiredo J; Velho S; Ribeiro AS; Soares P; Oliveira C; Seruca R
    J Pathol; 2008 Feb; 214(3):320-7. PubMed ID: 18098337
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas.
    Maddalena F; Condelli V; Matassa DS; Pacelli C; Scrima R; Lettini G; Li Bergolis V; Pietrafesa M; Crispo F; Piscazzi A; Storto G; Capitanio N; Esposito F; Landriscina M
    Mol Oncol; 2020 Dec; 14(12):3030-3047. PubMed ID: 33025742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors.
    Matassa DS; Agliarulo I; Amoroso MR; Maddalena F; Sepe L; Ferrari MC; Sagar V; D'Amico S; Loreni F; Paolella G; Landriscina M; Esposito F
    Mol Oncol; 2014 Dec; 8(8):1482-94. PubMed ID: 24962791
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells.
    Costantino E; Maddalena F; Calise S; Piscazzi A; Tirino V; Fersini A; Ambrosi A; Neri V; Esposito F; Landriscina M
    Cancer Lett; 2009 Jun; 279(1):39-46. PubMed ID: 19217207
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells.
    Tian X; Ma P; Sui CG; Meng FD; Li Y; Fu LY; Jiang T; Wang Y; Jiang YH
    FEBS J; 2014 Jun; 281(12):2805-19. PubMed ID: 24754231
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins.
    Friday BB; Yu C; Dy GK; Smith PD; Wang L; Thibodeau SN; Adjei AA
    Cancer Res; 2008 Aug; 68(15):6145-53. PubMed ID: 18676837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
    Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
    Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
    Matassa DS; Amoroso MR; Agliarulo I; Maddalena F; Sisinni L; Paladino S; Romano S; Romano MF; Sagar V; Loreni F; Landriscina M; Esposito F
    Cell Death Dis; 2013 Oct; 4(10):e851. PubMed ID: 24113185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo.
    Ouyang B; Knauf JA; Smith EP; Zhang L; Ramsey T; Yusuff N; Batt D; Fagin JA
    Clin Cancer Res; 2006 Mar; 12(6):1785-93. PubMed ID: 16551863
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma.
    Maddalena F; Simeon V; Vita G; Bochicchio A; Possidente L; Sisinni L; Lettini G; Condelli V; Matassa DS; Li Bergolis V; Fersini A; Romito S; Aieta M; Ambrosi A; Esposito F; Landriscina M
    Oncotarget; 2017 Mar; 8(13):21229-21240. PubMed ID: 28177905
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways.
    Agliarulo I; Matassa DS; Amoroso MR; Maddalena F; Sisinni L; Sepe L; Ferrari MC; Arzeni D; Avolio R; Paolella G; Landriscina M; Esposito F
    Biochim Biophys Acta; 2015 Oct; 1853(10 Pt A):2570-9. PubMed ID: 26071104
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients.
    Georgieva M; Krasteva M; Angelova E; Ralchev K; Dimitrov V; Bozhimirov S; Georgieva E; Berger MR
    Oncol Rep; 2008 Jul; 20(1):3-11. PubMed ID: 18575712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins.
    Amoroso MR; Matassa DS; Laudiero G; Egorova AV; Polishchuk RS; Maddalena F; Piscazzi A; Paladino S; Sarnataro D; Garbi C; Landriscina M; Esposito F
    Cell Death Differ; 2012 Apr; 19(4):592-604. PubMed ID: 21979464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer.
    Riesco-Eizaguirre G; Rodríguez I; De la Vieja A; Costamagna E; Carrasco N; Nistal M; Santisteban P
    Cancer Res; 2009 Nov; 69(21):8317-25. PubMed ID: 19861538
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.