BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1194 related articles for article (PubMed ID: 28673807)

  • 1. Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
    Geng YD; Zhang C; Lei JL; Yu P; Xia YZ; Zhang H; Yang L; Kong LY
    Biochem Pharmacol; 2017 Oct; 142():71-86. PubMed ID: 28673807
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gedunin isolated from the mangrove plant Xylocarpus granatum exerts its anti-proliferative activity in ovarian cancer cells through G2/M-phase arrest and oxidative stress-mediated intrinsic apoptosis.
    Sahai R; Bhattacharjee A; Shukla VN; Yadav P; Hasanain M; Sarkar J; Narender T; Mitra K
    Apoptosis; 2020 Aug; 25(7-8):481-499. PubMed ID: 32399945
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.
    Teng JF; Qin DL; Mei QB; Qiu WQ; Pan R; Xiong R; Zhao Y; Law BY; Wong VK; Tang Y; Yu CL; Zhang F; Wu JM; Wu AG
    Pharmacol Res; 2019 Sep; 147():104396. PubMed ID: 31404628
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk.
    Chen P; Luo X; Nie P; Wu B; Xu W; Shi X; Chang H; Li B; Yu X; Zou Z
    Free Radic Biol Med; 2017 Mar; 104():280-297. PubMed ID: 28131902
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
    Wu W; Ye H; Wan L; Han X; Wang G; Hu J; Tang M; Duan X; Fan Y; He S; Huang L; Pei H; Wang X; Li X; Xie C; Zhang R; Yuan Z; Mao Y; Wei Y; Chen L
    Carcinogenesis; 2013 Jul; 34(7):1636-43. PubMed ID: 23471882
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude mice.
    Chang CT; Hseu YC; Thiyagarajan V; Lin KY; Way TD; Korivi M; Liao JW; Yang HL
    Arch Toxicol; 2017 Oct; 91(10):3341-3364. PubMed ID: 28374157
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT; Zhong W; Sun P; Wang D; Wang C; Hu LM; Qian JQ
    J Ethnopharmacol; 2017 Mar; 200():107-116. PubMed ID: 28088493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells.
    de Souza Grinevicius VM; Kviecinski MR; Santos Mota NS; Ourique F; Porfirio Will Castro LS; Andreguetti RR; Gomes Correia JF; Filho DW; Pich CT; Pedrosa RC
    J Ethnopharmacol; 2016 Aug; 189():139-47. PubMed ID: 27178634
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TPP-related mitochondrial targeting copper (II) complex induces p53-dependent apoptosis in hepatoma cells through ROS-mediated activation of Drp1.
    Shao J; Li M; Guo Z; Jin C; Zhang F; Ou C; Xie Y; Tan S; Wang Z; Zheng S; Wang X
    Cell Commun Signal; 2019 Nov; 17(1):149. PubMed ID: 31744518
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-breast cancer and toxicity studies of total secondary saponin from Anemone raddeana Rhizome on MCF-7 cells via ROS generation and PI3K/AKT/mTOR inactivation.
    Zhang D; Zhang Q; Zheng Y; Lu J
    J Ethnopharmacol; 2020 Sep; 259():112984. PubMed ID: 32446927
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The first limonoid peroxide in the Meliaceae family: walsuronoid A from Walsura robusta.
    Yin S; Wang XN; Fan CQ; Liao SG; Yue JM
    Org Lett; 2007 Jun; 9(12):2353-6. PubMed ID: 17503836
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Juglanin induces apoptosis and autophagy in human breast cancer progression via ROS/JNK promotion.
    Sun ZL; Dong JL; Wu J
    Biomed Pharmacother; 2017 Jan; 85():303-312. PubMed ID: 27899257
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An oral 2-hydroxypropyl-β-cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma.
    Gao X; Wei M; Shan W; Liu Q; Gao J; Liu Y; Zhu S; Yao H
    Pharmacol Res; 2019 Oct; 148():104400. PubMed ID: 31425749
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
    Wang X; Bai H; Zhang X; Liu J; Cao P; Liao N; Zhang W; Wang Z; Hai C
    Carcinogenesis; 2013 Jun; 34(6):1323-30. PubMed ID: 23404993
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
    Liu Y; Fan D
    Biochem Pharmacol; 2019 Oct; 168():285-304. PubMed ID: 31301277
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bigelovin, a sesquiterpene lactone, suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation in liver cancer.
    Wang B; Zhou TY; Nie CH; Wan DL; Zheng SS
    Biochem Biophys Res Commun; 2018 May; 499(2):156-163. PubMed ID: 29548826
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
    Liu W; Ning R; Chen RN; Huang XF; Dai QS; Hu JH; Wang YW; Wu LL; Xiong J; Hu G; Guo QL; Yang J; Wang H
    Mol Carcinog; 2016 May; 55(5):440-57. PubMed ID: 25683703
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Downregulation of TIGAR sensitizes the antitumor effect of physapubenolide through increasing intracellular ROS levels to trigger apoptosis and autophagosome formation in human breast carcinoma cells.
    Ma T; Zhang Y; Zhang C; Luo JG; Kong LY
    Biochem Pharmacol; 2017 Nov; 143():90-106. PubMed ID: 28774732
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo.
    Hsu YL; Kuo PL; Tzeng TF; Sung SC; Yen MH; Lin LT; Lin CC
    J Gastroenterol Hepatol; 2008 Jul; 23(7 Pt 2):e290-9. PubMed ID: 18522681
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pentoxifylline induces apoptosis of HepG2 cells by reducing reactive oxygen species production and activating the MAPK signaling.
    Wang Y; Dong L; Li J; Luo M; Shang B
    Life Sci; 2017 Aug; 183():60-68. PubMed ID: 28583366
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 60.