224 related articles for article (PubMed ID: 29997176)
1. Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Sharma S; Čermáková K; De Rijck J; Demeulemeester J; Fábry M; El Ashkar S; Van Belle S; Lepšík M; Tesina P; Duchoslav V; Novák P; Hubálek M; Srb P; Christ F; Řezáčová P; Hodges HC; Debyser Z; Veverka V
Proc Natl Acad Sci U S A; 2018 Jul; 115(30):E7053-E7062. PubMed ID: 29997176
[TBL] [Abstract][Full Text] [Related]
2. Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.
Tesina P; Čermáková K; Hořejší M; Procházková K; Fábry M; Sharma S; Christ F; Demeulemeester J; Debyser Z; Rijck J; Veverka V; Řezáčová P
Nat Commun; 2015 Aug; 6():7968. PubMed ID: 26245978
[TBL] [Abstract][Full Text] [Related]
3. Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia.
Cermáková K; Tesina P; Demeulemeester J; El Ashkar S; Méreau H; Schwaller J; Rezáčová P; Veverka V; De Rijck J
Cancer Res; 2014 Sep; 74(18):5139-51. PubMed ID: 25082813
[TBL] [Abstract][Full Text] [Related]
4. Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.
Van Belle S; El Ashkar S; Čermáková K; Matthijssens F; Goossens S; Canella A; Hodges CH; Christ F; De Rijck J; Van Vlierberghe P; Veverka V; Debyser Z
Cells; 2021 Jan; 10(1):. PubMed ID: 33477970
[TBL] [Abstract][Full Text] [Related]
5. Impairing MLL-fusion gene-mediated transformation by dissecting critical interactions with the lens epithelium-derived growth factor (LEDGF/p75).
Méreau H; De Rijck J; Cermáková K; Kutz A; Juge S; Demeulemeester J; Gijsbers R; Christ F; Debyser Z; Schwaller J
Leukemia; 2013 Jun; 27(6):1245-53. PubMed ID: 23318960
[TBL] [Abstract][Full Text] [Related]
6. Lessons Learned: HIV Points the Way Towards Precision Treatment of Mixed-Lineage Leukemia.
Cermakova K; Weydert C; Christ F; De Rijck J; Debyser Z
Trends Pharmacol Sci; 2016 Aug; 37(8):660-671. PubMed ID: 27290878
[TBL] [Abstract][Full Text] [Related]
7. LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis.
El Ashkar S; Schwaller J; Pieters T; Goossens S; Demeulemeester J; Christ F; Van Belle S; Juge S; Boeckx N; Engelman A; Van Vlierberghe P; Debyser Z; De Rijck J
Blood; 2018 Jan; 131(1):95-107. PubMed ID: 29084774
[TBL] [Abstract][Full Text] [Related]
8. Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins.
Pradeepa MM; Grimes GR; Taylor GC; Sutherland HG; Bickmore WA
Nucleic Acids Res; 2014 Aug; 42(14):9021-32. PubMed ID: 25056311
[TBL] [Abstract][Full Text] [Related]
9. LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs.
Schrijvers R; De Rijck J; Demeulemeester J; Adachi N; Vets S; Ronen K; Christ F; Bushman FD; Debyser Z; Gijsbers R
PLoS Pathog; 2012; 8(3):e1002558. PubMed ID: 22396646
[TBL] [Abstract][Full Text] [Related]
10. The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.
Murai MJ; Pollock J; He S; Miao H; Purohit T; Yokom A; Hess JL; Muntean AG; Grembecka J; Cierpicki T
Blood; 2014 Dec; 124(25):3730-7. PubMed ID: 25305204
[TBL] [Abstract][Full Text] [Related]
11. Structure-based virtual screening toward the discovery of novel inhibitors for impeding the protein-protein interaction between HIV-1 integrase and human lens epithelium-derived growth factor (LEDGF/p75).
Panwar U; Singh SK
J Biomol Struct Dyn; 2018 Sep; 36(12):3199-3217. PubMed ID: 28948865
[TBL] [Abstract][Full Text] [Related]
12. Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75.
Lapaillerie D; Lelandais B; Mauro E; Lagadec F; Tumiotto C; Miskey C; Ferran G; Kuschner N; Calmels C; Métifiot M; Rooryck C; Ivics Z; Ruff M; Zimmer C; Lesbats P; Toutain J; Parissi V
Nucleic Acids Res; 2021 Nov; 49(19):11241-11256. PubMed ID: 34634812
[TBL] [Abstract][Full Text] [Related]
13. Menin critically links MLL proteins with LEDGF on cancer-associated target genes.
Yokoyama A; Cleary ML
Cancer Cell; 2008 Jul; 14(1):36-46. PubMed ID: 18598942
[TBL] [Abstract][Full Text] [Related]
14. The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.
Brouns T; Lux V; Van Belle S; Christ F; Veverka V; Debyser Z
Cells; 2024 Jan; 13(3):. PubMed ID: 38334618
[TBL] [Abstract][Full Text] [Related]
15. The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells.
Ortiz-Hernandez GL; Sanchez-Hernandez ES; Ochoa PT; Elix CC; Alkashgari HR; McMullen JRW; Soto U; Martinez SR; Diaz Osterman CJ; Mahler M; Roy S; Casiano CA
Cells; 2021 Oct; 10(10):. PubMed ID: 34685704
[TBL] [Abstract][Full Text] [Related]
16. LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors.
Meehan AM; Saenz DT; Morrison JH; Garcia-Rivera JA; Peretz M; Llano M; Poeschla EM
PLoS Pathog; 2009 Jul; 5(7):e1000522. PubMed ID: 19609362
[TBL] [Abstract][Full Text] [Related]
17. A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75.
Hare S; Shun MC; Gupta SS; Valkov E; Engelman A; Cherepanov P
PLoS Pathog; 2009 Jan; 5(1):e1000259. PubMed ID: 19132083
[TBL] [Abstract][Full Text] [Related]
18. A role for LEDGF/p75 in targeting HIV DNA integration.
Ciuffi A; Llano M; Poeschla E; Hoffmann C; Leipzig J; Shinn P; Ecker JR; Bushman F
Nat Med; 2005 Dec; 11(12):1287-9. PubMed ID: 16311605
[TBL] [Abstract][Full Text] [Related]
19. Zinc finger endonuclease targeting PSIP1 inhibits HIV-1 integration.
Badia R; Pauls E; Riveira-Munoz E; Clotet B; Esté JA; Ballana E
Antimicrob Agents Chemother; 2014 Aug; 58(8):4318-27. PubMed ID: 24820090
[TBL] [Abstract][Full Text] [Related]
20. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication.
Lopez AP; Kugelman JR; Garcia-Rivera J; Urias E; Salinas SA; Fernandez-Zapico ME; Llano M
J Mol Biol; 2016 Jul; 428(14):2814-31. PubMed ID: 27216501
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]