BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

300 related articles for article (PubMed ID: 33182787)

  • 1. Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2.
    Ortega-Alarcon D; Claveria-Gimeno R; Vega S; Jorge-Torres OC; Esteller M; Abian O; Velazquez-Campoy A
    Biomolecules; 2020 Nov; 10(11):. PubMed ID: 33182787
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Influence of the disordered domain structure of MeCP2 on its structural stability and dsDNA interaction.
    Ortega-Alarcon D; Claveria-Gimeno R; Vega S; Jorge-Torres OC; Esteller M; Abian O; Velazquez-Campoy A
    Int J Biol Macromol; 2021 Apr; 175():58-66. PubMed ID: 33548325
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural, Dynamical, and Energetical Consequences of Rett Syndrome Mutation R133C in MeCP2.
    Kucukkal TG; Alexov E
    Comput Math Methods Med; 2015; 2015():746157. PubMed ID: 26064184
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo.
    Kumar A; Kamboj S; Malone BM; Kudo S; Twiss JL; Czymmek KJ; LaSalle JM; Schanen NC
    J Cell Sci; 2008 Apr; 121(Pt 7):1128-37. PubMed ID: 18334558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tyr120Asp mutation alters domain flexibility and dynamics of MeCP2 DNA binding domain leading to impaired DNA interaction: Atomistic characterization of a Rett syndrome causing mutation.
    D'Annessa I; Gandaglia A; Brivio E; Stefanelli G; Frasca A; Landsberger N; Di Marino D
    Biochim Biophys Acta Gen Subj; 2018 May; 1862(5):1180-1189. PubMed ID: 29428602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rett syndrome-causing mutations in human MeCP2 result in diverse structural changes that impact folding and DNA interactions.
    Ghosh RP; Horowitz-Scherer RA; Nikitina T; Gierasch LM; Woodcock CL
    J Biol Chem; 2008 Jul; 283(29):20523-34. PubMed ID: 18499664
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice.
    Heckman LD; Chahrour MH; Zoghbi HY
    Elife; 2014 Jun; 3():. PubMed ID: 24970834
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.
    Tillotson R; Selfridge J; Koerner MV; Gadalla KKE; Guy J; De Sousa D; Hector RD; Cobb SR; Bird A
    Nature; 2017 Oct; 550(7676):398-401. PubMed ID: 29019980
    [TBL] [Abstract][Full Text] [Related]  

  • 9.
    Anitha A; Poovathinal SA; Viswambharan V; Thanseem I; Iype M; Anoop U; Sumitha PS; Parakkal R; Vasu MM
    Neurol India; 2022; 70(1):249-253. PubMed ID: 35263890
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The impact of MECP2 mutations in the expression patterns of Rett syndrome patients.
    Ballestar E; Ropero S; Alaminos M; Armstrong J; Setien F; Agrelo R; Fraga MF; Herranz M; Avila S; Pineda M; Monros E; Esteller M
    Hum Genet; 2005 Jan; 116(1-2):91-104. PubMed ID: 15549394
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA binding restricts the intrinsic conformational flexibility of methyl CpG binding protein 2 (MeCP2).
    Hansen JC; Wexler BB; Rogers DJ; Hite KC; Panchenko T; Ajith S; Black BE
    J Biol Chem; 2011 May; 286(21):18938-48. PubMed ID: 21467044
    [TBL] [Abstract][Full Text] [Related]  

  • 12. From Function to Phenotype: Impaired DNA Binding and Clustering Correlates with Clinical Severity in Males with Missense Mutations in MECP2.
    Sheikh TI; Ausió J; Faghfoury H; Silver J; Lane JB; Eubanks JH; MacLeod P; Percy AK; Vincent JB
    Sci Rep; 2016 Dec; 6():38590. PubMed ID: 27929079
    [TBL] [Abstract][Full Text] [Related]  

  • 13. First report of an unusual novel double mutation affecting the transcription repression domain of MeCP2 and causing a severe phenotype of Rett syndrome: Molecular analyses and computational investigation.
    Ghorbel R; Ghorbel R; Rouissi A; Fendri-Kriaa N; Ben Salah G; Belguith N; Ammar-Keskes L; Gouider-Khouja N; Fakhfakh F
    Biochem Biophys Res Commun; 2018 Feb; 497(1):93-101. PubMed ID: 29421650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MECP2 mutation spectrum and its clinical characteristics in a Chinese cohort.
    Wen Y; Wang J; Zhang Q; Chen Y; Wu X; Bao X
    Clin Genet; 2020 Sep; 98(3):240-250. PubMed ID: 32472557
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MeCP2 AT-Hook1 mutations in patients with intellectual disability and/or schizophrenia disrupt DNA binding and chromatin compaction in vitro.
    Sheikh TI; Harripaul R; Ayub M; Vincent JB
    Hum Mutat; 2018 May; 39(5):717-728. PubMed ID: 29431277
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2.
    Ortega-Alarcon D; Claveria-Gimeno R; Vega S; Jorge-Torres OC; Esteller M; Abian O; Velazquez-Campoy A
    Biomolecules; 2021 Aug; 11(8):. PubMed ID: 34439881
    [TBL] [Abstract][Full Text] [Related]  

  • 17. P152R Mutation Within MeCP2 Can Cause Loss of DNA-Binding Selectivity.
    Franklin D
    Interdiscip Sci; 2019 Mar; 11(1):10-20. PubMed ID: 30673959
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MeCP2 dysfunction in Rett syndrome and related disorders.
    Moretti P; Zoghbi HY
    Curr Opin Genet Dev; 2006 Jun; 16(3):276-81. PubMed ID: 16647848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutational analysis of the MECP2 gene in Japanese patients with Rett syndrome.
    Amano K; Nomura Y; Segawa M; Yamakawa K
    J Hum Genet; 2000; 45(4):231-6. PubMed ID: 10944854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome.
    Brown K; Selfridge J; Lagger S; Connelly J; De Sousa D; Kerr A; Webb S; Guy J; Merusi C; Koerner MV; Bird A
    Hum Mol Genet; 2016 Feb; 25(3):558-70. PubMed ID: 26647311
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.