BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 34514747)

  • 1. Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy.
    Lei JH; Lee MH; Miao K; Huang Z; Yao Z; Zhang A; Xu J; Zhao M; Huang Z; Zhang X; Chen S; Jiaying NG; Feng Y; Xing F; Chen P; Sun H; Chen Q; Xiang T; Chen L; Xu X; Deng CX
    Adv Sci (Weinh); 2021 Nov; 8(21):e2100974. PubMed ID: 34514747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FGFR2-BRD4 Axis Regulates Transcriptional Networks of Histone 3 Modification and Synergy Between Its Inhibitors and PD-1/PD-L1 in a TNBC Mouse Model.
    Lei JH; Zhang L; Wang Z; Peltier R; Xie Y; Chen G; Lin S; Miao K; Deng CX; Sun H
    Front Immunol; 2022; 13():861221. PubMed ID: 35547739
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers.
    Blanchard Z; Paul BT; Craft B; ElShamy WM
    Breast Cancer Res; 2015 Jan; 17(1):5. PubMed ID: 25583261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway.
    Li P; Huang T; Zou Q; Liu D; Wang Y; Tan X; Wei Y; Qiu H
    J Immunol; 2019 May; 202(10):3065-3075. PubMed ID: 30979816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Emerging strategies: PARP inhibitors in combination with immune checkpoint blockade in BRCA1 and BRCA2 mutation-associated and triple-negative breast cancer.
    Gupta T; Vinayak S; Telli M
    Breast Cancer Res Treat; 2023 Jan; 197(1):51-56. PubMed ID: 36318381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The breast cancer susceptibility gene product fibroblast growth factor receptor 2 serves as a scaffold for regulation of NF-κB signaling.
    Wei W; Liu W; Cassol CA; Zheng W; Asa SL; Ezzat S
    Mol Cell Biol; 2012 Nov; 32(22):4662-73. PubMed ID: 22988296
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
    Zhang J; Wong CC; Leung KT; Wu F; Zhou Y; Tong JHM; Chan RCK; Li H; Wang Y; Yan H; Liu L; Wu WKK; Chan MWY; Cheng ASL; Yu J; Wong N; Lo KW; To KF; Kang W
    Oncogene; 2020 Oct; 39(43):6647-6663. PubMed ID: 32934314
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Determining Factors in the Therapeutic Success of Checkpoint Immunotherapies against PD-L1 in Breast Cancer: A Focus on Epithelial-Mesenchymal Transition Activation.
    Segovia-Mendoza M; Romero-Garcia S; Lemini C; Prado-Garcia H
    J Immunol Res; 2021; 2021():6668573. PubMed ID: 33506060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis.
    Lu P; Ewald AJ; Martin GR; Werb Z
    Dev Biol; 2008 Sep; 321(1):77-87. PubMed ID: 18585375
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis.
    Shukla V; Coumoul X; Wang RH; Kim HS; Deng CX
    Nat Genet; 2007 Sep; 39(9):1145-50. PubMed ID: 17694057
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function.
    Pond AC; Bin X; Batts T; Roarty K; Hilsenbeck S; Rosen JM
    Stem Cells; 2013 Jan; 31(1):178-89. PubMed ID: 23097355
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade.
    Bai X; Zhou Y; Yokota Y; Matsumoto Y; Zhai B; Maarouf N; Hayashi H; Carlson R; Zhang S; Sousa A; Sun B; Ghanbari H; Dong X; Wands JR
    J Exp Clin Cancer Res; 2022 Apr; 41(1):132. PubMed ID: 35392977
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice.
    Burga LN; Hu H; Juvekar A; Tung NM; Troyan SL; Hofstatter EW; Wulf GM
    Breast Cancer Res; 2011 Mar; 13(2):R30. PubMed ID: 21396117
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study.
    Cunningham DL; Sarhan AR; Creese AJ; Larkins KPB; Zhao H; Ferguson HR; Brookes K; Marusiak AA; Cooper HJ; Heath JK
    Sci Rep; 2020 May; 10(1):7950. PubMed ID: 32409632
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.
    Ma Y; Katiyar P; Jones LP; Fan S; Zhang Y; Furth PA; Rosen EM
    Mol Endocrinol; 2006 Jan; 20(1):14-34. PubMed ID: 16109739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FGFR2-related pathogenesis and FGFR2-targeted therapeutics (Review).
    Katoh Y; Katoh M
    Int J Mol Med; 2009 Mar; 23(3):307-11. PubMed ID: 19212647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aberrantly activated Wnt/β-catenin pathway co-receptors LRP5 and LRP6 regulate osteoblast differentiation in the developing coronal sutures of an Apert syndrome (Fgfr2
    Min Swe NM; Kobayashi Y; Kamimoto H; Moriyama K
    Dev Dyn; 2021 Mar; 250(3):465-476. PubMed ID: 32822074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets.
    Lee HJ; Seo AN; Park SY; Kim JY; Park JY; Yu JH; Ahn JH; Gong G
    Ann Surg Oncol; 2014 May; 21(5):1561-8. PubMed ID: 24385208
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
    Huang T; Liu D; Wang Y; Li P; Sun L; Xiong H; Dai Y; Zou M; Yuan X; Qiu H
    Cell Physiol Biochem; 2018; 50(4):1332-1345. PubMed ID: 30355943
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Ser252Trp substitution in mouse FGFR2 results in hyperplasia of embryonic salivary gland parenchyma.
    Watanabe T; Kometani-Gunjigake K; Nakao-Kuroishi K; Ito-Sago M; Mizuhara M; Iwata D; Moriyama K; Ono K; Kawamoto T
    J Oral Biosci; 2021 Jun; 63(2):184-191. PubMed ID: 33684522
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.