BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 34710747)

  • 1. Human estrogen receptor α antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants.
    Kurtanović N; Tomašević N; Matić S; Mitrović MM; Kostić DA; Sabatino M; Antonini L; Ragno R; Mladenović M
    Eur J Med Chem; 2022 Jan; 227():113869. PubMed ID: 34710747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coumarin-Fatty Acid Conjugates as Potential ERα/AKT-1 Antagonists for ER Positive Breast Cancer.
    Selvaraj J; John JBA; Joghee NM; Antony J; Wadhwani A; Natarajan J
    Anticancer Agents Med Chem; 2020; 20(4):437-449. PubMed ID: 31746305
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of novel benzothiophene analogs as selective estrogen receptor covalent antagonists against breast cancer.
    Bai C; Ren S; Wu S; Zhu M; Luo G; Xiang H
    Eur J Med Chem; 2021 Oct; 221():113543. PubMed ID: 34022716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human Estrogen Receptor α Antagonists. Part 1: 3-D QSAR-Driven Rational Design of Innovative Coumarin-Related Antiestrogens as Breast Cancer Suppressants through Structure-Based and Ligand-Based Studies.
    Mihović N; Tomašević N; Matić S; Mitrović MM; Kostić DA; Sabatino M; Antonini L; Ragno R; Mladenović M
    J Chem Inf Model; 2021 Oct; 61(10):5028-5053. PubMed ID: 34648283
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity.
    Ragab MA; Elagawany M; Daabees H; Ahmed AF; Awad EM; Billon C; Elgendy B; Abouzid KAM; Kassab SE
    Bioorg Chem; 2022 Feb; 119():105554. PubMed ID: 34923243
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Estrogen Receptor α (ERα)-targeting Compounds and Derivatives: Recent Advances in Structural Modification and Bioactivity.
    Guo WY; Zeng SM; Deora GS; Li QS; Ruan BF
    Curr Top Med Chem; 2019; 19(15):1318-1337. PubMed ID: 31215379
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and Synthesis of Some Novel Estrogen Receptor Modulators as Anti-Breast Cancer Agents: In Vitro & In Vivo Screening, Docking Analysis.
    Dube PN; Mokale SN
    Anticancer Agents Med Chem; 2016; 16(11):1461-1467. PubMed ID: 26863879
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual functional small molecule fluorescent probes for image-guided estrogen receptor-specific targeting coupled potent antiproliferative potency for breast cancer therapy.
    Yang L; Hu Z; Luo J; Tang C; Zhang S; Ning W; Dong C; Huang J; Liu X; Zhou HB
    Bioorg Med Chem; 2017 Jul; 25(13):3531-3539. PubMed ID: 28506582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of novel tetrahydroisoquinoline-hydroxamate conjugates as potent dual SERDs/HDAC inhibitors for the treatment of breast cancer.
    Luo G; Lin X; Ren S; Wu S; Wang X; Ma L; Xiang H
    Eur J Med Chem; 2021 Dec; 226():113870. PubMed ID: 34610548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel hybrid conjugates with dual estrogen receptor α degradation and histone deacetylase inhibitory activities for breast cancer therapy.
    Zhao C; Tang C; Li C; Ning W; Hu Z; Xin L; Zhou HB; Huang J
    Bioorg Med Chem; 2021 Jun; 40():116185. PubMed ID: 33965842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERα
    Puyang X; Furman C; Zheng GZ; Wu ZJ; Banka D; Aithal K; Agoulnik S; Bolduc DM; Buonamici S; Caleb B; Das S; Eckley S; Fekkes P; Hao MH; Hart A; Houtman R; Irwin S; Joshi JJ; Karr C; Kim A; Kumar N; Kumar P; Kuznetsov G; Lai WG; Larsen N; Mackenzie C; Martin LA; Melchers D; Moriarty A; Nguyen TV; Norris J; O'Shea M; Pancholi S; Prajapati S; Rajagopalan S; Reynolds DJ; Rimkunas V; Rioux N; Ribas R; Siu A; Sivakumar S; Subramanian V; Thomas M; Vaillancourt FH; Wang J; Wardell S; Wick MJ; Yao S; Yu L; Warmuth M; Smith PG; Zhu P; Korpal M
    Cancer Discov; 2018 Sep; 8(9):1176-1193. PubMed ID: 29991605
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Screening Estrogen Receptor Modulators in a Paper-Based Breast Cancer Model.
    Whitman NA; Lin ZW; DiProspero TJ; McIntosh JC; Lockett MR
    Anal Chem; 2018 Oct; 90(20):11981-11988. PubMed ID: 30226366
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New estrogen receptor antagonists. 3,20-Dihydroxy-19-norpregna-1,3,5(10)-trienes: Synthesis, molecular modeling, and biological evaluation.
    Kuznetsov YV; Levina IS; Scherbakov AM; Andreeva OE; Fedyushkina IV; Dmitrenok AS; Shashkov AS; Zavarzin IV
    Eur J Med Chem; 2018 Jan; 143():670-682. PubMed ID: 29220789
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity.
    Luo G; Tang Z; Lao K; Li X; You Q; Xiang H
    Eur J Med Chem; 2018 Apr; 150():783-795. PubMed ID: 29587221
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel Hybrid Conjugates with Dual Suppression of Estrogenic and Inflammatory Activities Display Significantly Improved Potency against Breast Cancer.
    Ning W; Hu Z; Tang C; Yang L; Zhang S; Dong C; Huang J; Zhou HB
    J Med Chem; 2018 Sep; 61(18):8155-8173. PubMed ID: 30053783
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissues.
    Saha P; Descôteaux C; Brasseur K; Fortin S; Leblanc V; Parent S; Asselin E; Bérubé G
    Eur J Med Chem; 2012 Feb; 48():385-90. PubMed ID: 22209414
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, biological evaluation and molecular docking studies of novel 3-aryl-4-anilino-2H-chromen-2-one derivatives targeting ERα as anti-breast cancer agents.
    Luo G; Chen M; Lyu W; Zhao R; Xu Q; You Q; Xiang H
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2668-2673. PubMed ID: 28460819
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells.
    Carr M; Knox AJ; Lloyd DG; Zisterer DM; Meegan MJ
    J Enzyme Inhib Med Chem; 2016; 31(sup3):117-130. PubMed ID: 27476825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, Synthesis and Biological Evaluation of 4, 6-Coumarin Derivatives as Anti- Cancer and Apoptosis-Inducing Agents.
    Yan G; Luo J; Han X; Zhang W; Pu C; Zhou M; Zhong X; Hou X; Hou MZ; Li R
    Anticancer Agents Med Chem; 2021; 21(17):2351-2367. PubMed ID: 33511941
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.