BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 37906251)

  • 1. Synergistic roles of DYRK1A and GATA1 in trisomy 21 megakaryopoiesis.
    Sit YT; Takasaki K; An HH; Xiao Y; Hurtz C; Gearhart PA; Zhang Z; Gadue P; French DL; Chou ST
    JCI Insight; 2023 Oct; 8(23):. PubMed ID: 37906251
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model.
    Arkoun B; Robert E; Boudia F; Mazzi S; Dufour V; Siret A; Mammasse Y; Aid Z; Vieira M; Imanci A; Aglave M; Cambot M; Petermann R; Souquere S; Rameau P; Catelain C; Diot R; Tachdjian G; Hermine O; Droin N; Debili N; Plo I; Malinge S; Soler E; Raslova H; Mercher T; Vainchenker W
    J Clin Invest; 2022 Jul; 132(14):. PubMed ID: 35587378
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification.
    Matsuo S; Nishinaka-Arai Y; Kazuki Y; Oshimura M; Nakahata T; Niwa A; Saito MK
    PLoS One; 2021; 16(3):e0247595. PubMed ID: 33780474
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of
    Barwe SP; Sebastian A; Sidhu I; Kolb EA; Gopalakrishnapillai A
    Cells; 2022 Feb; 11(4):. PubMed ID: 35203280
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Generation of 2 isogenic clones from a patient with Trisomy 21 and a GATA1 mutation.
    Takasaki K; Kumar SS; Gagne A; French DL; Chou ST
    Stem Cell Res; 2023 Jun; 69():103098. PubMed ID: 37084616
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Generation of CHOPi-008-B, a euploid iPSC line from a patient with Trisomy 21 and a GATA1 mutation.
    Takasaki K; Kumar SS; Gagne A; French DL; Chou ST
    Stem Cell Res; 2023 Oct; 72():103198. PubMed ID: 37677872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia.
    Klusmann JH; Li Z; Böhmer K; Maroz A; Koch ML; Emmrich S; Godinho FJ; Orkin SH; Reinhardt D
    Genes Dev; 2010 Mar; 24(5):478-90. PubMed ID: 20194440
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome.
    Alford KA; Slender A; Vanes L; Li Z; Fisher EM; Nizetic D; Orkin SH; Roberts I; Tybulewicz VL
    Blood; 2010 Apr; 115(14):2928-37. PubMed ID: 20154221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Germline GATA1s-generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype.
    Hasle H; Kline RM; Kjeldsen E; Nik-Abdul-Rashid NF; Bhojwani D; Verboon JM; DiTroia SP; Chao KR; Raaschou-Jensen K; Palle J; Zwaan CM; Nyvold CG; Sankaran VG; Cantor AB
    Blood; 2022 May; 139(21):3159-3165. PubMed ID: 34758059
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.
    Xavier AC; Edwards H; Dombkowski AA; Balci TB; Berman JN; Dellaire G; Xie C; Buck SA; Matherly LH; Ge Y; Taub JW
    PLoS One; 2011; 6(11):e27486. PubMed ID: 22110660
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies.
    Kazuki Y; Yakura Y; Abe S; Osaki M; Kajitani N; Kazuki K; Takehara S; Honma K; Suemori H; Yamazaki S; Sakuma T; Toki T; Shimizu R; Nakauchi H; Yamamoto T; Oshimura M
    Sci Rep; 2014 Aug; 4():6136. PubMed ID: 25159877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.
    Malinge S; Bliss-Moreau M; Kirsammer G; Diebold L; Chlon T; Gurbuxani S; Crispino JD
    J Clin Invest; 2012 Mar; 122(3):948-62. PubMed ID: 22354171
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21.
    Rainis L; Bercovich D; Strehl S; Teigler-Schlegel A; Stark B; Trka J; Amariglio N; Biondi A; Muler I; Rechavi G; Kempski H; Haas OA; Izraeli S
    Blood; 2003 Aug; 102(3):981-6. PubMed ID: 12649131
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells.
    Stankiewicz MJ; Crispino JD
    Blood; 2009 Apr; 113(14):3337-47. PubMed ID: 19168790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [GATA1-mutation associated leukemia in children with trisomy 21 mosaic].
    Reinhardt D; Reinhardt K; Neuhoff C; Sander A; Klusmann JH; Pekrun A; Sauerbrey A; von Stackelberg A; Rössig C; Creutzig U; Kolenova A
    Klin Padiatr; 2012 Apr; 224(3):153-5. PubMed ID: 22513796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia.
    Kanezaki R; Toki T; Terui K; Xu G; Wang R; Shimada A; Hama A; Kanegane H; Kawakami K; Endo M; Hasegawa D; Kogawa K; Adachi S; Ikeda Y; Iwamoto S; Taga T; Kosaka Y; Kojima S; Hayashi Y; Ito E
    Blood; 2010 Nov; 116(22):4631-8. PubMed ID: 20729467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome.
    Xu G; Kanezaki R; Toki T; Watanabe S; Takahashi Y; Terui K; Kitabayashi I; Ito E
    Leukemia; 2006 Jun; 20(6):1002-8. PubMed ID: 16628190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia.
    Maroz A; Stachorski L; Emmrich S; Reinhardt K; Xu J; Shao Z; Käbler S; Dertmann T; Hitzler J; Roberts I; Vyas P; Juban G; Hennig C; Hansen G; Li Z; Orkin S; Reinhardt D; Klusmann JH
    Leukemia; 2014 Jun; 28(6):1259-70. PubMed ID: 24336126
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Morphologic and GATA1 sequencing analysis of hematopoiesis in fetuses with trisomy 21.
    Hoeller S; Bihl MP; Tzankov A; Chaffard R; Hirschmann P; Miny P; Kühne T; Bruder E
    Hum Pathol; 2014 May; 45(5):1003-9. PubMed ID: 24746204
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.
    Bourquin JP; Subramanian A; Langebrake C; Reinhardt D; Bernard O; Ballerini P; Baruchel A; Cavé H; Dastugue N; Hasle H; Kaspers GL; Lessard M; Michaux L; Vyas P; van Wering E; Zwaan CM; Golub TR; Orkin SH
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3339-44. PubMed ID: 16492768
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.