187 related articles for article (PubMed ID: 38200309)
1. MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Cho MG; Kumar RJ; Lin CC; Boyer JA; Shahir JA; Fagan-Solis K; Simpson DA; Fan C; Foster CE; Goddard AM; Lerner LM; Ellington SW; Wang Q; Wang Y; Ho AY; Liu P; Perou CM; Zhang Q; McGinty RK; Purvis JE; Gupta GP
Nature; 2024 Jan; 625(7995):585-592. PubMed ID: 38200309
[TBL] [Abstract][Full Text] [Related]
2. A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability.
Fagan-Solis KD; Simpson DA; Kumar RJ; Martelotto LG; Mose LE; Rashid NU; Ho AY; Powell SN; Wen YH; Parker JS; Reis-Filho JS; Petrini JHJ; Gupta GP
Cell Rep; 2020 Feb; 30(5):1385-1399.e7. PubMed ID: 32023457
[TBL] [Abstract][Full Text] [Related]
3. Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Liu H; Zhang H; Wu X; Ma D; Wu J; Wang L; Jiang Y; Fei Y; Zhu C; Tan R; Jungblut P; Pei G; Dorhoi A; Yan Q; Zhang F; Zheng R; Liu S; Liang H; Liu Z; Yang H; Chen J; Wang P; Tang T; Peng W; Hu Z; Xu Z; Huang X; Wang J; Li H; Zhou Y; Liu F; Yan D; Kaufmann SHE; Chen C; Mao Z; Ge B
Nature; 2018 Nov; 563(7729):131-136. PubMed ID: 30356214
[TBL] [Abstract][Full Text] [Related]
4. MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.
Spehalski E; Capper KM; Smith CJ; Morgan MJ; Dinkelmann M; Buis J; Sekiguchi JM; Ferguson DO
Cancer Res; 2017 Oct; 77(19):5327-5338. PubMed ID: 28819025
[TBL] [Abstract][Full Text] [Related]
5. Structural basis for nucleosome-mediated inhibition of cGAS activity.
Cao D; Han X; Fan X; Xu RM; Zhang X
Cell Res; 2020 Dec; 30(12):1088-1097. PubMed ID: 33051594
[TBL] [Abstract][Full Text] [Related]
6. Structural mechanism of cGAS inhibition by the nucleosome.
Pathare GR; Decout A; Glück S; Cavadini S; Makasheva K; Hovius R; Kempf G; Weiss J; Kozicka Z; Guey B; Melenec P; Fierz B; Thomä NH; Ablasser A
Nature; 2020 Nov; 587(7835):668-672. PubMed ID: 32911482
[TBL] [Abstract][Full Text] [Related]
7. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11.
Piscitello D; Varshney D; Lilla S; Vizioli MG; Reid C; Gorbunova V; Seluanov A; Gillespie DA; Adams PD
Oncogene; 2018 Jan; 37(4):427-438. PubMed ID: 28967905
[TBL] [Abstract][Full Text] [Related]
8. Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis.
Rodriguez DA; Quarato G; Liedmann S; Tummers B; Zhang T; Guy C; Crawford JC; Palacios G; Pelletier S; Kalkavan H; Shaw JJP; Fitzgerald P; Chen MJ; Balachandran S; Green DR
Proc Natl Acad Sci U S A; 2022 Oct; 119(41):e2207240119. PubMed ID: 36191211
[TBL] [Abstract][Full Text] [Related]
9. Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Michalski S; de Oliveira Mann CC; Stafford CA; Witte G; Bartho J; Lammens K; Hornung V; Hopfner KP
Nature; 2020 Nov; 587(7835):678-682. PubMed ID: 32911480
[TBL] [Abstract][Full Text] [Related]
10. The molecular basis of tight nuclear tethering and inactivation of cGAS.
Zhao B; Xu P; Rowlett CM; Jing T; Shinde O; Lei Y; West AP; Liu WR; Li P
Nature; 2020 Nov; 587(7835):673-677. PubMed ID: 32911481
[TBL] [Abstract][Full Text] [Related]
11. Structural basis of nucleosome-dependent cGAS inhibition.
Boyer JA; Spangler CJ; Strauss JD; Cesmat AP; Liu P; McGinty RK; Zhang Q
Science; 2020 Oct; 370(6515):450-454. PubMed ID: 32913000
[TBL] [Abstract][Full Text] [Related]
12. DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.
Kondo T; Kobayashi J; Saitoh T; Maruyama K; Ishii KJ; Barber GN; Komatsu K; Akira S; Kawai T
Proc Natl Acad Sci U S A; 2013 Feb; 110(8):2969-74. PubMed ID: 23388631
[TBL] [Abstract][Full Text] [Related]
13. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
14. cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers.
Hong C; Schubert M; Tijhuis AE; Requesens M; Roorda M; van den Brink A; Ruiz LA; Bakker PL; van der Sluis T; Pieters W; Chen M; Wardenaar R; van der Vegt B; Spierings DCJ; de Bruyn M; van Vugt MATM; Foijer F
Nature; 2022 Jul; 607(7918):366-373. PubMed ID: 35705809
[TBL] [Abstract][Full Text] [Related]
15. MRE11-RAD50-NBS1 complex alterations and DNA damage response: implications for cancer treatment.
Bian L; Meng Y; Zhang M; Li D
Mol Cancer; 2019 Nov; 18(1):169. PubMed ID: 31767017
[TBL] [Abstract][Full Text] [Related]
16. STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS).
Messaoud-Nacer Y; Culerier E; Rose S; Maillet I; Rouxel N; Briault S; Ryffel B; Quesniaux VFJ; Togbe D
Cell Death Dis; 2022 Mar; 13(3):269. PubMed ID: 35338116
[TBL] [Abstract][Full Text] [Related]
17. RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy.
Liu W; Zheng M; Zhang R; Jiang Q; Du G; Wu Y; Yang C; Li F; Li W; Wang L; Wu J; Shi L; Li W; Zhang K; Zhou Z; Liu R; Gao Y; Huang X; Fan S; Zhi X; Jiang D; Chen C
Adv Sci (Weinh); 2023 Feb; 10(5):e2203884. PubMed ID: 36563124
[TBL] [Abstract][Full Text] [Related]
18. Manganese facilitated cGAS-STING-IFNI pathway activation induced by ionizing radiation in glioma cells.
He Y; Yang Y; Huang W; Yang S; Xue X; Zhu K; Tan H; Sun T; Yang W
Int J Radiat Biol; 2023; 99(12):1890-1907. PubMed ID: 37406172
[TBL] [Abstract][Full Text] [Related]
19. Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene.
Bartkova J; Tommiska J; Oplustilova L; Aaltonen K; Tamminen A; Heikkinen T; Mistrik M; Aittomäki K; Blomqvist C; Heikkilä P; Lukas J; Nevanlinna H; Bartek J
Mol Oncol; 2008 Dec; 2(4):296-316. PubMed ID: 19383352
[TBL] [Abstract][Full Text] [Related]
20. FGFR2 regulates Mre11 expression and double-strand break repair via the MEK-ERK-POU1F1 pathway in breast tumorigenesis.
Huang YL; Chou WC; Hsiung CN; Hu LY; Chu HW; Shen CY
Hum Mol Genet; 2015 Jun; 24(12):3506-17. PubMed ID: 25788520
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]