BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

76 related articles for article (PubMed ID: 38744825)

  • 1. Hyperactive mTORC1/4EBP1 Signaling Dysregulates Proteostasis and Accelerates Cardiac Aging.
    Zarzycka W; Kobak KA; King CJ; Peelor FF; Miller BF; Chiao YA
    bioRxiv; 2024 May; ():. PubMed ID: 38798509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism.
    Levy T; Voeltzke K; Hruby L; Alasad K; Bas Z; Snaebjörnsson M; Marciano R; Scharov K; Planque M; Vriens K; Christen S; Funk CM; Hassiepen C; Kahler A; Heider B; Picard D; Lim JKM; Stefanski A; Bendrin K; Vargas-Toscano A; Kahlert UD; Stühler K; Remke M; Elkabets M; Grünewald TGP; Reichert AS; Fendt SM; Schulze A; Reifenberger G; Rotblat B; Leprivier G
    Nat Commun; 2024 May; 15(1):4083. PubMed ID: 38744825
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic target of rapamycin inhibitors: successes and challenges as cancer therapeutics.
    Bhaoighill MN; Dunlop EA
    Cancer Drug Resist; 2019; 2(4):1069-1085. PubMed ID: 35582282
    [TBL] [Abstract][Full Text] [Related]  

  • 4. EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma.
    Voeltzke K; Scharov K; Funk CM; Kahler A; Picard D; Hauffe L; Orth MF; Remke M; Esposito I; Kirchner T; Schramm A; Rotblat B; Grünewald TGP; Reifenberger G; Leprivier G
    Cell Death Discov; 2022 Apr; 8(1):157. PubMed ID: 35379801
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation.
    Hauffe L; Picard D; Musa J; Remke M; Grünewald TGP; Rotblat B; Reifenberger G; Leprivier G
    Cell Death Discov; 2022 Feb; 8(1):91. PubMed ID: 35228525
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AMPK: restoring metabolic homeostasis over space and time.
    Trefts E; Shaw RJ
    Mol Cell; 2021 Sep; 81(18):3677-3690. PubMed ID: 34547233
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Survival analysis across the entire transcriptome identifies biomarkers with the highest prognostic power in breast cancer.
    Győrffy B
    Comput Struct Biotechnol J; 2021; 19():4101-4109. PubMed ID: 34527184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deep computational analysis details dysregulation of eukaryotic translation initiation complex eIF4F in human cancers.
    Wu S; Wagner G
    Cell Syst; 2021 Sep; 12(9):907-923.e6. PubMed ID: 34358439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data from Chinese Glioma Patients.
    Zhao Z; Zhang KN; Wang Q; Li G; Zeng F; Zhang Y; Wu F; Chai R; Wang Z; Zhang C; Zhang W; Bao Z; Jiang T
    Genomics Proteomics Bioinformatics; 2021 Feb; 19(1):1-12. PubMed ID: 33662628
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity.
    Conn CS; Yang H; Tom HJ; Ikeda K; Oses-Prieto JA; Vu H; Oguri Y; Nair S; Gill RM; Kajimura S; DeBerardinis RJ; Burlingame AL; Ruggero D
    Nat Metab; 2021 Feb; 3(2):244-257. PubMed ID: 33619378
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glioma cells require one-carbon metabolism to survive glutamine starvation.
    Tanaka K; Sasayama T; Nagashima H; Irino Y; Takahashi M; Izumi Y; Uno T; Satoh N; Kitta A; Kyotani K; Fujita Y; Hashiguchi M; Nakai T; Kohta M; Uozumi Y; Shinohara M; Hosoda K; Bamba T; Kohmura E
    Acta Neuropathol Commun; 2021 Jan; 9(1):16. PubMed ID: 33468252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications.
    Ju HQ; Lin JF; Tian T; Xie D; Xu RH
    Signal Transduct Target Ther; 2020 Oct; 5(1):231. PubMed ID: 33028807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular logic of mTORC1 signalling as a metabolic rheostat.
    Valvezan AJ; Manning BD
    Nat Metab; 2019 Mar; 1(3):321-333. PubMed ID: 32694720
    [TBL] [Abstract][Full Text] [Related]  

  • 14. How does mTOR sense glucose starvation? AMPK is the usual suspect.
    Leprivier G; Rotblat B
    Cell Death Discov; 2020; 6():27. PubMed ID: 32351714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mTOR at the nexus of nutrition, growth, ageing and disease.
    Liu GY; Sabatini DM
    Nat Rev Mol Cell Biol; 2020 Apr; 21(4):183-203. PubMed ID: 31937935
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1.
    Yoon I; Nam M; Kim HK; Moon HS; Kim S; Jang J; Song JA; Jeong SJ; Kim SB; Cho S; Kim Y; Lee J; Yang WS; Yoo HC; Kim K; Kim MS; Yang A; Cho K; Park HS; Hwang GS; Hwang KY; Han JM; Kim JH; Kim S
    Science; 2020 Jan; 367(6474):205-210. PubMed ID: 31780625
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphofructokinases Axis Controls Glucose-Dependent mTORC1 Activation Driven by E2F1.
    Almacellas E; Pelletier J; Manzano A; Gentilella A; Ambrosio S; Mauvezin C; Tauler A
    iScience; 2019 Oct; 20():434-448. PubMed ID: 31627130
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.
    Tameire F; Verginadis II; Leli NM; Polte C; Conn CS; Ojha R; Salas Salinas C; Chinga F; Monroy AM; Fu W; Wang P; Kossenkov A; Ye J; Amaravadi RK; Ignatova Z; Fuchs SY; Diehl JA; Ruggero D; Koumenis C
    Nat Cell Biol; 2019 Jul; 21(7):889-899. PubMed ID: 31263264
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 4.