185 related articles for article (PubMed ID: 38755145)
1. TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression.
Garcia-Montojo M; Fathi S; Rastegar C; Simula ER; Doucet-O'Hare T; Cheng YHH; Abrams RPM; Pasternack N; Malik N; Bachani M; Disanza B; Maric D; Lee MH; Wang H; Santamaria U; Li W; Sampson K; Lorenzo JR; Sanchez IE; Mezghrani A; Li Y; Sechi LA; Pineda S; Heiman M; Kellis M; Steiner J; Nath A
Nat Commun; 2024 May; 15(1):4163. PubMed ID: 38755145
[TBL] [Abstract][Full Text] [Related]
2. Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders.
Janssens J; Van Broeckhoven C
Hum Mol Genet; 2013 Oct; 22(R1):R77-87. PubMed ID: 23900071
[TBL] [Abstract][Full Text] [Related]
3. PABPN1 suppresses TDP-43 toxicity in ALS disease models.
Chou CC; Alexeeva OM; Yamada S; Pribadi A; Zhang Y; Mo B; Williams KR; Zarnescu DC; Rossoll W
Hum Mol Genet; 2015 Sep; 24(18):5154-73. PubMed ID: 26130692
[TBL] [Abstract][Full Text] [Related]
4. RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
Ihara R; Matsukawa K; Nagata Y; Kunugi H; Tsuji S; Chihara T; Kuranaga E; Miura M; Wakabayashi T; Hashimoto T; Iwatsubo T
Hum Mol Genet; 2013 Nov; 22(22):4474-84. PubMed ID: 23804749
[TBL] [Abstract][Full Text] [Related]
5. Quantitative patterns of motor cortex proteinopathy across ALS genotypes.
Nolan M; Scott C; Gamarallage MP; Lunn D; Carpenter K; McDonough E; Meyer D; Kaanumalle S; Santamaria-Pang A; Turner MR; Talbot K; Ansorge O
Acta Neuropathol Commun; 2020 Jul; 8(1):98. PubMed ID: 32616036
[TBL] [Abstract][Full Text] [Related]
6. Mislocalization of Nup62 Contributes to TDP-43 Proteinopathy in ALS/FTLD.
Nag N; Tripathi T
ACS Chem Neurosci; 2022 Sep; 13(17):2544-2546. PubMed ID: 36001801
[TBL] [Abstract][Full Text] [Related]
7. Disease animal models of TDP-43 proteinopathy and their pre-clinical applications.
Liu YC; Chiang PM; Tsai KJ
Int J Mol Sci; 2013 Oct; 14(10):20079-111. PubMed ID: 24113586
[TBL] [Abstract][Full Text] [Related]
8. TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Wang P; Deng J; Dong J; Liu J; Bigio EH; Mesulam M; Wang T; Sun L; Wang L; Lee AY; McGee WA; Chen X; Fushimi K; Zhu L; Wu JY
PLoS Genet; 2019 May; 15(5):e1007947. PubMed ID: 31100073
[TBL] [Abstract][Full Text] [Related]
9. Endogenous retroviruses and TDP-43 proteinopathy form a sustaining feedback driving intercellular spread of Drosophila neurodegeneration.
Chang YH; Dubnau J
Nat Commun; 2023 Feb; 14(1):966. PubMed ID: 36810738
[TBL] [Abstract][Full Text] [Related]
10. TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration.
Gao J; Wang L; Yan T; Perry G; Wang X
Mol Cell Neurosci; 2019 Oct; 100():103396. PubMed ID: 31445085
[TBL] [Abstract][Full Text] [Related]
11. Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD.
Kumar S; Phaneuf D; Cordeau P; Boutej H; Kriz J; Julien JP
Mol Neurodegener; 2021 Jan; 16(1):1. PubMed ID: 33413517
[TBL] [Abstract][Full Text] [Related]
12. Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery.
Hunter M; Spiller KJ; Dominique MA; Xu H; Hunter FW; Fang TC; Canter RG; Roberts CJ; Ransohoff RM; Trojanowski JQ; Lee VM
Acta Neuropathol Commun; 2021 Aug; 9(1):140. PubMed ID: 34412701
[TBL] [Abstract][Full Text] [Related]
13. RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy.
Chen HJ; Topp SD; Hui HS; Zacco E; Katarya M; McLoughlin C; King A; Smith BN; Troakes C; Pastore A; Shaw CE
Brain; 2019 Dec; 142(12):3753-3770. PubMed ID: 31605140
[TBL] [Abstract][Full Text] [Related]
14. TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets.
Scotter EL; Chen HJ; Shaw CE
Neurotherapeutics; 2015 Apr; 12(2):352-63. PubMed ID: 25652699
[TBL] [Abstract][Full Text] [Related]
15. Progranulin and TDP-43: mechanistic links and future directions.
Kumar-Singh S
J Mol Neurosci; 2011 Nov; 45(3):561-73. PubMed ID: 21863317
[TBL] [Abstract][Full Text] [Related]
16. Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy.
Spiller KJ; Cheung CJ; Restrepo CR; Kwong LK; Stieber AM; Trojanowski JQ; Lee VM
J Neurosci; 2016 Jul; 36(29):7707-17. PubMed ID: 27445147
[TBL] [Abstract][Full Text] [Related]
17. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
Chew J; Cook C; Gendron TF; Jansen-West K; Del Rosso G; Daughrity LM; Castanedes-Casey M; Kurti A; Stankowski JN; Disney MD; Rothstein JD; Dickson DW; Fryer JD; Zhang YJ; Petrucelli L
Mol Neurodegener; 2019 Feb; 14(1):9. PubMed ID: 30767771
[TBL] [Abstract][Full Text] [Related]
18. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
[TBL] [Abstract][Full Text] [Related]
19. Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD.
Wood A; Gurfinkel Y; Polain N; Lamont W; Lyn Rea S
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946763
[TBL] [Abstract][Full Text] [Related]
20. Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy.
Costantino I; Meng A; Ravits J
Acta Neuropathol; 2024 May; 147(1):93. PubMed ID: 38814471
[No Abstract] [Full Text] [Related]
[Next] [New Search]
