Terms: = Brain cancer AND NFE2L2, ENSG00000116044, 4780, Q16236, NRF2 AND Treatment
76 results:
1. Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Kurmasheva N; Said A; Wong B; Kinderman P; Han X; Rahimic AHF; Kress A; Carter-Timofte ME; Holm E; van der Horst D; Kollmann CF; Liu Z; Wang C; Hoang HD; Kovalenko E; Chrysopoulou M; Twayana KS; Ottosen RN; Svenningsen EB; Begnini F; Kiib AE; Kromm FEH; Weiss HJ; Di Carlo D; Muscolini M; Higgins M; van der Heijden M; Bardoul A; Tong T; Ozsvar A; Hou WH; Schack VR; Holm CK; Zheng Y; Ruzek M; Kalucka J; de la Vega L; Elgaher WAM; Korshoej AR; Lin R; Hiscott J; Poulsen TB; O'Neill LA; Roy DG; Rinschen MM; van Montfoort N; Diallo JS; Farin HF; Alain T; Olagnier D
Nat Commun; 2024 May; 15(1):4096. PubMed ID: 38750019
[TBL] [Abstract] [Full Text] [Related]
2. Orexin-A mediates glioblastoma proliferation inhibition by increasing ferroptosis triggered by unstable iron pools and GPX4 depletion.
Huan R; Zhang J; Yue J; Yang S; Han G; Cheng Y; Tan Y
J Cell Mol Med; 2024 May; 28(9):e18318. PubMed ID: 38685674
[TBL] [Abstract] [Full Text] [Related]
3. Meningioma achieves malignancy and erastin-induced ferroptosis resistance through FOXM1-AURKA-nrf2 axis.
Ye Y; Xu L; Zhang L; Zhao P; Cai W; Fu G; Wang T; Tao Z; Shi W; Gu W; Hu J; Yuan G; Wei Y; Xu K; Bao Z; Chao H; Liu N; Zhao L; Tu Y; Ji J
Redox Biol; 2024 Jun; 72():103137. PubMed ID: 38642502
[TBL] [Abstract] [Full Text] [Related]
4. Hydroethanolic extract of Cirsium setidens ameliorates doxorubicin-induced cardiotoxicity by AMPK-PGC-1α-SOD-mediated mitochondrial protection.
Song JH; Kim MS; Lee SH; Hwang JT; Park SH; Park SW; Jeon SB; Lee RR; Lee J; Choi HK
Phytomedicine; 2024 Jul; 129():155633. PubMed ID: 38640859
[TBL] [Abstract] [Full Text] [Related]
5. Therapeutic potential of targeting nrf2 by panobinostat in pituitary neuroendocrine tumors.
Cheng Y; Dai Y; Tang H; Lu X; Xie J; Xie W; Zhang Q; Liu Y; Lin S; Yao H; Shang H; Yang K; Liu H; Wu X; Zhang J; Zhang X; Xue L; Wu ZB
Acta Neuropathol Commun; 2024 Apr; 12(1):61. PubMed ID: 38637883
[TBL] [Abstract] [Full Text] [Related]
6. Borax induces ferroptosis of glioblastoma by targeting HSPA5/nrf2/GPx4/GSH pathways.
Tuncer C; Hacioglu C
J Cell Mol Med; 2024 Apr; 28(7):e18206. PubMed ID: 38494858
[TBL] [Abstract] [Full Text] [Related]
7. Design, synthesis and biological evaluation of nrf2 modulators for the treatment of glioblastoma multiforme.
Yang H; Song P; Li B; Li S; Yang J
Bioorg Med Chem; 2024 Apr; 103():117684. PubMed ID: 38493731
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8. A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma.
Singh S; Lathoria K; Umdor SB; Singh J; Suri V; Sen E
Cytokine; 2024 Apr; 176():156535. PubMed ID: 38325141
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9. CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma.
Li Y; Yang C; Xie L; Shi F; Tang M; Luo X; Liu N; Hu X; Zhu Y; Bode AM; Gao Q; Zhou J; Fan J; Li X; Cao Y
Cell Death Dis; 2024 Jan; 15(1):95. PubMed ID: 38287022
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10. SLC38A5 Modulates Ferroptosis to Overcome Gemcitabine Resistance in Pancreatic cancer.
Kim MJ; Kim HS; Kang HW; Lee DE; Hong WC; Kim JH; Kim M; Cheong JH; Kim HJ; Park JS
Cells; 2023 Oct; 12(20):. PubMed ID: 37887353
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11. Licochalcone A: A Potential Multitarget Drug for Alzheimer's Disease treatment.
Olloquequi J; Ettcheto M; Cano A; Fortuna A; Bicker J; Sánchez-Lopez E; Paz C; Ureña J; Verdaguer E; Auladell C; Camins A
Int J Mol Sci; 2023 Sep; 24(18):. PubMed ID: 37762479
[TBL] [Abstract] [Full Text] [Related]
12. S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome.
Yang YH; Li W; Ren LW; Yang H; Zhang YZ; Zhang S; Hao Y; Yu DK; Tong RS; Du GH; Shi JY; Wang JH
Acta Pharmacol Sin; 2024 Jan; 45(1):209-222. PubMed ID: 37749236
[TBL] [Abstract] [Full Text] [Related]
13. nrf2 Signaling Pathway: a Potential Therapeutic Target in Combating Oxidative Stress and Neurotoxicity in Chemotherapy-Induced Cognitive Impairment.
Lal R; Dharavath RN; Chopra K
Mol Neurobiol; 2024 Feb; 61(2):593-608. PubMed ID: 37644279
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14. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
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15. NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via nrf2/SOD2 Modulation.
Su IC; Su YK; Setiawan SA; Yadav VK; Fong IH; Yeh CT; Lin CM; Liu HW
Int J Mol Sci; 2023 Apr; 24(9):. PubMed ID: 37175412
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16. Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Liang C; Yi K; Zhou X; Li X; Zhong C; Cao H; Xie C; Zhu J
Phytother Res; 2023 Jul; 37(7):2995-3008. PubMed ID: 36866538
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17. Identification of a copper metabolism-related gene signature for predicting prognosis and immune response in glioma.
Li L; Leng W; Chen J; Li S; Lei B; Zhang H; Zhao H
Cancer Med; 2023 Apr; 12(8):10123-10137. PubMed ID: 36856182
[TBL] [Abstract] [Full Text] [Related]
18. CircOMA1 modulates cabergoline resistance by downregulating ferroptosis in prolactinoma.
Wu N; Zhu D; Li J; Li X; Zhu Z; Rao Q; Hu B; Wang H; Zhu Y
J Endocrinol Invest; 2023 Aug; 46(8):1573-1587. PubMed ID: 36853491
[TBL] [Abstract] [Full Text] [Related]
19. Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via nrf2.
Liu Y; Chou FJ; Lang F; Zhang M; Song H; Zhang W; Davis DL; Briceno NJ; Zhang Y; Cimino PJ; Zaghloul KA; Gilbert MR; Armstrong TS; Yang C
Clin Cancer Res; 2023 Apr; 29(7):1305-1316. PubMed ID: 36648507
[TBL] [Abstract] [Full Text] [Related]
20. Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.
Linke F; Johnson JEC; Kern S; Bennett CD; Lourdusamy A; Lea D; Clifford SC; Merry CLR; Stolnik S; Alexander MR; Peet AC; Scurr DJ; Griffiths RL; Grabowska AM; Kerr ID; Coyle B
Acta Neuropathol Commun; 2023 Jan; 11(1):6. PubMed ID: 36631900
[TBL] [Abstract] [Full Text] [Related]
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