BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND NTRK3, TRKC, 4916, ENSG00000140538, Q16288, gp145 trkC AND Treatment
42 results:

  • 1. ETV6::ntrk3 gene fusion in a patient with metastatic lung atypical carcinoid successfully treated with repotrectinib: A case report.
    Gao L; Ai X; Lu S
    Lung Cancer; 2024 Jan; 187():107443. PubMed ID: 38113652
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  • 2. Long Non-coding RNA and mRNA Co-expression Network Reveals Novel Players in Pleomorphic Xanthoastrocytoma.
    Dandapath I; Gupta R; Singh J; Shukla N; Jha P; Sharma V; Suri A; Sharma MC; Suri V; Sarkar C; Kulshreshtha R
    Mol Neurobiol; 2022 Aug; 59(8):5149-5167. PubMed ID: 35674862
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  • 3. Larotrectinib Response in ntrk3 Fusion-Driven Diffuse High-Grade Glioma.
    König D; Hench J; Frank S; Dima L; Bratic Hench I; Läubli H
    Pharmacology; 2022; 107(7-8):433-438. PubMed ID: 35526519
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  • 4. LINC02381-ceRNA exerts its oncogenic effect through regulation of IGF1R signaling pathway in glioma.
    Nemati H; Fakhre-Taha M; Javanmard AR; Jahanbakhshi A; Mowla SJ; Soltani BM
    J Neurooncol; 2022 May; 158(1):1-13. PubMed ID: 35460500
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  • 5. Undifferentiated and Unresectable Sarcoma With ntrk3-Fusion in a Pediatric Patient Treated With Larotrectinib and Proton Beam Radiotherapy.
    Olsen MR; Denu RA; Lyon JB; Gulliver JM; Capitini CM; DeSantes KB
    J Pediatr Hematol Oncol; 2022 Apr; 44(3):e770-e774. PubMed ID: 34862354
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  • 6. Detection of NTRK fusions in glioblastoma: fluorescent in situ hybridisation is more useful than pan-TRK immunohistochemistry as a screening tool prior to RNA sequencing.
    Bourhis A; Caumont C; Quintin-Roué I; Magro E; Dissaux G; Remoué A; Le Noac'h P; Douet-Guilbert N; Seizeur R; Tyulyandina A; Schick U; Merlio JP; Marcorelles P; Cappellen D; Uguen A
    Pathology; 2022 Feb; 54(1):55-62. PubMed ID: 34518039
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  • 7. Case of multifocal glioblastoma with four fusion transcripts of
    Samii A; Sorokin M; Kar S; Makovskaia L; Garazha A; Hartmann C; Moisseev A; Kim E; Giese A; Buzdin A
    Cold Spring Harb Mol Case Stud; 2021 Aug; 7(4):. PubMed ID: 34341009
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  • 8. Adjuvant Maintenance Larotrectinib Therapy in 2 Children With NTRK Fusion-positive High-grade Cancers.
    Carter-Febres M; Schneller N; Fair D; Solomon D; Perry A; Roy A; Linscott L; Alashari M; Kestle JR; Bruggers CS
    J Pediatr Hematol Oncol; 2021 Oct; 43(7):e987-e990. PubMed ID: 33093355
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  • 9. Central nervous system ganglioneuroblastoma harboring MYO5A-ntrk3 fusion.
    Ito J; Nakano Y; Shima H; Miwa T; Kogure Y; Isshiki K; Yamazaki F; Oishi Y; Morimoto Y; Kataoka K; Okita H; Hirato J; Ichimura K; Shimada H
    Brain Tumor Pathol; 2020 Jul; 37(3):105-110. PubMed ID: 32556925
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  • 10. NTRK and ALK rearrangements in malignant pleural mesothelioma, pulmonary neuroendocrine tumours and non-small cell lung cancer.
    Leal JL; Peters G; Szaumkessel M; Leong T; Asadi K; Rivalland G; Do H; Senko C; Mitchell PL; Quing CZ; Dobrovic A; Thapa B; John T
    Lung Cancer; 2020 Aug; 146():154-159. PubMed ID: 32540558
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  • 11. Differential Clinical Significance of Neurotrophin-3 Expression according to MYCN Amplification and trkc Expression in Neuroblastoma.
    Seo E; Kim JS; Ma YE; Cho HW; Ju HY; Lee SH; Lee JW; Yoo KH; Sung KW; Koo HH
    J Korean Med Sci; 2019 Oct; 34(39):e254. PubMed ID: 31602824
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  • 12. Entrectinib and other ALK/TRK inhibitors for the treatment of neuroblastoma.
    Pacenta HL; Macy ME
    Drug Des Devel Ther; 2018; 12():3549-3561. PubMed ID: 30425456
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  • 13. Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma.
    Ziegler DS; Wong M; Mayoh C; Kumar A; Tsoli M; Mould E; Tyrrell V; Khuong-Quang DA; Pinese M; Gayevskiy V; Cohn RJ; Lau LMS; Reynolds M; Cox MC; Gifford A; Rodriguez M; Cowley MJ; Ekert PG; Marshall GM; Haber M
    Br J Cancer; 2018 Sep; 119(6):693-696. PubMed ID: 30220707
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  • 14. Arsenic trioxide induces cell cycle arrest and affects Trk receptor expression in human neuroblastoma SK-N-SH cells.
    Xiong X; Li Y; Liu L; Qi K; Zhang C; Chen Y; Fang J
    Biol Res; 2018 Jun; 51(1):18. PubMed ID: 29898774
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  • 15. Activity of Entrectinib in a Patient With the First Reported
    Sigal D; Tartar M; Xavier M; Bao F; Foley P; Luo D; Christiansen J; Hornby Z; Maneval EC; Multani P
    J Natl Compr Canc Netw; 2017 Nov; 15(11):1317-1322. PubMed ID: 29118225
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  • 16. Tropomyosin receptor kinase C (trkc) expression in medulloblastoma: relation to the molecular subgroups and impact on treatment response.
    Friedrich C; Shalaby T; Oehler C; Pruschy M; Seifert B; Picard D; Remke M; Warmuth-Metz M; Kortmann RD; Rutkowski S; Grotzer MA; von Bueren AO
    Childs Nerv Syst; 2017 Sep; 33(9):1463-1471. PubMed ID: 28695340
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  • 17. Autophagy and trkc/NT-3 signaling joined forces boost the hypoxic glioblastoma cell survival.
    Jawhari S; Bessette B; Hombourger S; Durand K; Lacroix A; Labrousse F; Jauberteau MO; Ratinaud MH; Verdier M
    Carcinogenesis; 2017 Jun; 38(6):592-603. PubMed ID: 28402394
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  • 18. Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions.
    Vanden Borre P; Schrock AB; Anderson PM; Morris JC; Heilmann AM; Holmes O; Wang K; Johnson A; Waguespack SG; Ou SI; Khan S; Fung KM; Stephens PJ; Erlich RL; Miller VA; Ross JS; Ali SM
    Oncologist; 2017 Mar; 22(3):255-263. PubMed ID: 28209747
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  • 19. Neurotrophin signaling via TrkB and trkc receptors promotes the growth of brain tumor-initiating cells.
    Lawn S; Krishna N; Pisklakova A; Qu X; Fenstermacher DA; Fournier M; Vrionis FD; Tran N; Chan JA; Kenchappa RS; Forsyth PA
    J Biol Chem; 2015 Feb; 290(6):3814-24. PubMed ID: 25538243
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  • 20. p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.
    Forsyth PA; Krishna N; Lawn S; Valadez JG; Qu X; Fenstermacher DA; Fournier M; Potthast L; Chinnaiyan P; Gibney GT; Zeinieh M; Barker PA; Carter BD; Cooper MK; Kenchappa RS
    J Biol Chem; 2014 Mar; 289(12):8067-85. PubMed ID: 24519935
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