BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND SDHB, PGL4, 6390, ENSG00000117118, SDH1, SDHIP, SDH, IP AND Treatment
285 results:

  • 1. Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress.
    Lu Z; Sun GF; He KY; Zhang Z; Han XH; Qu XH; Wan DF; Yao D; Tou FF; Han XJ; Wang T
    Biochim Biophys Acta Mol Basis Dis; 2024 Jun; 1870(5):167220. PubMed ID: 38718847
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
    Chen X; Yang T; Zhou Y; Mei Z; Zhang W
    CNS Neurosci Ther; 2024 Apr; 30(4):e14725. PubMed ID: 38615367
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Cabozantinib in patients with unresectable and progressive metastatic phaeochromocytoma or paraganglioma (the Natalie Trial): a single-arm, phase 2 trial.
    Jimenez C; Habra MA; Campbell MT; Tamsen G; Cruz-Goldberg D; Long J; Bassett R; Dantzer R; Balderrama-Brondani V; Varghese J; Lu Y
    Lancet Oncol; 2024 May; 25(5):658-667. PubMed ID: 38608693
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. [Clinical features of patients with metastatic pheochromocytoma/paraganglioma].
    Cui YY; Zhou Y; Gao YJ; Li TY; Wang Y; Zhang WQ; Zhou T; Chen S; Tong AL
    Zhonghua Yi Xue Za Zhi; 2024 Apr; 104(14):1174-1179. PubMed ID: 38583049
    [No Abstract]    [Full Text] [Related]  

  • 5. Sex-related differences in serum biomarker levels predict the activity and efficacy of immune checkpoint inhibitors in advanced melanoma and non-small cell lung cancer patients.
    Pasello G; Fabricio ASC; Del Bianco P; Salizzato V; Favaretto A; Piccin L; Zustovich F; Fabozzi A; De Rossi C; Pigozzo J; De Nuzzo M; Cappelletto E; Bonanno L; Palleschi D; De Salvo GL; Guarneri V; Gion M; Chiarion-Sileni V
    J Transl Med; 2024 Mar; 22(1):242. PubMed ID: 38443899
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. TRIM25 promotes glioblastoma cell growth and invasion via regulation of the PRMT1/c-MYC pathway by targeting the splicing factor NONO.
    Chen Y; Xu X; Ding K; Tang T; Cai F; Zhang H; Chen Z; Qi Y; Fu Z; Zhu G; Dou Z; Xu J; Chen G; Wu Q; Ji J; Zhang J
    J Exp Clin Cancer Res; 2024 Feb; 43(1):39. PubMed ID: 38303029
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Outcomes of systemic treatment according to germline mutational status in patients with metastatic pheochromocytoma and paraganglioma.
    Park YG; Park I; Kim Y; Lee HS; Lee W; Yoon S; Lee JL
    Clin Genitourin Cancer; 2024 Apr; 22(2):413-419. PubMed ID: 38228412
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Management of phaeochromocytoma and paraganglioma in patients with germline sdhb pathogenic variants: an international expert Consensus statement.
    Taïeb D; Nölting S; Perrier ND; Fassnacht M; Carrasquillo JA; Grossman AB; Clifton-Bligh R; Wanna GB; Schwam ZG; Amar L; Bourdeau I; Casey RT; Crona J; Deal CL; Del Rivero J; Duh QY; Eisenhofer G; Fojo T; Ghayee HK; Gimenez-Roqueplo AP; Gill AJ; Hicks R; Imperiale A; Jha A; Kerstens MN; de Krijger RR; Lacroix A; Lazurova I; Lin FI; Lussey-Lepoutre C; Maher ER; Mete O; Naruse M; Nilubol N; Robledo M; Sebag F; Shah NS; Tanabe A; Thompson GB; Timmers HJLM; Widimsky J; Young WJ; Meuter L; Lenders JWM; Pacak K
    Nat Rev Endocrinol; 2024 Mar; 20(3):168-184. PubMed ID: 38097671
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Long-Term Intracranial Outcomes With Combination Dual Immune-Checkpoint Blockade and Stereotactic Radiosurgery in Patients With Melanoma and Non-Small cell Lung Cancer Brain Metastases.
    Vaios EJ; Shenker RF; Hendrickson PG; Wan Z; Niedzwiecki D; Winter SF; Shih HA; Dietrich J; Wang C; Salama AKS; Clarke JM; Allen K; Sperduto P; Mullikin T; Kirkpatrick JP; Floyd SR; Reitman ZJ
    Int J Radiat Oncol Biol Phys; 2024 Apr; 118(5):1507-1518. PubMed ID: 38097090
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
    Wang Z; Cai H; Li Z; Sun W; Zhao E; Cui H
    Clin Epigenetics; 2023 Dec; 15(1):192. PubMed ID: 38093312
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Longitudinal Natural History Study of Children and Adults with Rare Solid tumors: Initial Results for First 200 Participants.
    Ahmed S; Wedekind MF; Del Rivero J; Raygada M; Lockridge R; Glod JW; Flowers C; Thomas BJ; Bernstein DB; Kapustina OB; Jain A; Miettinen M; Raffeld M; Xi L; Tyagi M; Kim J; Aldape K; Malayeri AA; Kaplan RN; Allen T; Vivelo CA; Sandler AB; Widemann BC; Reilly KM;
    Cancer Res Commun; 2023 Dec; 3(12):2468-2482. PubMed ID: 37966258
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Significance of Social Determinants of Health in tumor Presentation, Hospital Readmission, and Overall Survival in Ocular Oncology.
    Choudhry HS; Patel AM; Nguyen HN; Kaleem MA; Handa JT
    Am J Ophthalmol; 2024 Apr; 260():21-29. PubMed ID: 37956780
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study.
    Fischer A; Kloos S; Remde H; Dischinger U; Pamporaki C; Timmers HJLM; Robledo M; Fliedner SMJ; Wang K; Maurer J; Reul A; Bechmann N; Hantel C; Mohr H; Pellegata NS; Bornstein SR; Kroiss M; Auernhammer CJ; Reincke M; Pacak K; Grossman AB; Beuschlein F; Nölting S
    Eur J Endocrinol; 2023 Nov; 189(5):546-565. PubMed ID: 37949483
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A novel RBBP8(p.E281*) germline mutation is a predisposing mutation in familial hereditary cancer syndrome.
    Yan J; Wu J; Wang Y; Di X; Jiang H; Wen D; Li D; Zhang S
    J Mol Med (Berl); 2023 Oct; 101(10):1255-1265. PubMed ID: 37615686
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Bioinformatics and Experimental Identification of
    Ma M; Xie D; Zhao J
    J Integr Neurosci; 2023 Jul; 22(4):105. PubMed ID: 37519165
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The role of neoadjuvant chemotherapy in the management of metastatic central nervous system germinoma: A meta-analysis.
    Abu-Arja MH; Shatara MS; Okcu MF; McGovern SL; Su JM; Abdelbaki MS
    Pediatr Blood Cancer; 2023 Oct; 70(10):e30601. PubMed ID: 37501569
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. CCNB1IP1 prevents ubiquitination-mediated destabilization of MYCN and potentiates tumourigenesis of MYCN-amplificated neuroblastoma.
    Zhou Y; Yan H; Zhou Q; Wang P; Yang F; Yuan Z; Du Q; Zhai B
    Clin Transl Med; 2023 Jul; 13(7):e1328. PubMed ID: 37461251
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. SDC1-TGM2-FLOT1-BHMT complex determines radiosensitivity of glioblastoma by influencing the fusion of autophagosomes with lysosomes.
    Zeng L; Zheng W; Liu X; Zhou Y; Jin X; Xiao Y; Bai Y; Pan Y; Zhang J; Shao C
    Theranostics; 2023; 13(11):3725-3743. PubMed ID: 37441590
    [No Abstract]    [Full Text] [Related]  

  • 19. Reduced uptake pattern on
    de Jong MC; Pinto D; Parameswaran R
    J Surg Oncol; 2023 Oct; 128(5):764-768. PubMed ID: 37403579
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. SPI1-mediated MIR222HG transcription promotes proneural-to-mesenchymal transition of glioma stem cells and immunosuppressive polarization of macrophages.
    Fan Y; Gao Z; Xu J; Wang H; Guo Q; Li B; Li M; Xu H; Qi Y; Zhao S; Qiu W; Pan Z; Wang Q; Xue H; Zhao R; Guo X; Li G
    Theranostics; 2023; 13(10):3310-3329. PubMed ID: 37351164
    [No Abstract]    [Full Text] [Related]  


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