BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND AFF3, MLLT2-like, 3899, ENSG00000144218, LAF4, P51826
30 results:

  • 1. Prominence of NUDT15 genetic variation associated with 6-mercaptopurine tolerance in a genome-wide association study of Japanese children with acute lymphoblastic leukaemia.
    Tanaka Y; Urayama KY; Mori M; Arakawa Y; Hasegawa D; Noguchi Y; Yanagimachi M; Keino D; Ota S; Akahane K; Inukai T; Hangai M; Kawaguchi T; Takagi M; Koh K; Matsuda F; Manabe A
    Br J Haematol; 2022 Oct; 199(2):260-269. PubMed ID: 35961941
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A complex KMT2A::aff3 fusion resulting from a three-way chromosomal rearrangement in pediatric B lymphoblastic leukemia.
    Miller LJ; Leventaki V; Harker-Murray PD; Drendel HM; Bone KM
    Cancer Genet; 2022 Apr; 262-263():43-46. PubMed ID: 34995897
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Discovery of Berberine that Targetedly Induces Autophagic Degradation of both BCR-ABL and BCR-ABL T315I through Recruiting LRSAM1 for Overcoming Imatinib Resistance.
    Yin Z; Huang G; Gu C; Liu Y; Yang J; Fei J
    Clin Cancer Res; 2020 Aug; 26(15):4040-4053. PubMed ID: 32098768
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Cancer incidence in familial Mediterranean fever patients: a retrospective analysis from central Anatolia.
    Bilgin E; Dizdar Ö; Güven DC; Ceylan S; Aybi Ö; Fırlatan B; Kardaş RC; Yıldırım T; Hayran MK; Kalyoncu U; Özen S
    Rheumatol Int; 2019 Jun; 39(6):1045-1051. PubMed ID: 31025139
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. laf4/aff3, a gene involved in intellectual disability, is required for cellular migration in the mouse cerebral cortex.
    Moore JM; Oliver PL; Finelli MJ; Lee S; Lickiss T; Molnár Z; Davies KE
    PLoS One; 2014; 9(8):e105933. PubMed ID: 25162227
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output.
    Luo Z; Lin C; Guest E; Garrett AS; Mohaghegh N; Swanson S; Marshall S; Florens L; Washburn MP; Shilatifard A
    Mol Cell Biol; 2012 Jul; 32(13):2608-17. PubMed ID: 22547686
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Hematopoietic stem cell transplantation rates and long-term survival in acute myeloid and lymphoblastic leukemia: real-world population-based data from the Swedish Acute leukemia Registry 1997-2006.
    Juliusson G; Karlsson K; Lazarevic VLj; Wahlin A; Brune M; Antunovic P; Derolf A; Hägglund H; Karbach H; Lehmann S; Möllgård L; Stockelberg D; Hallböök H; Höglund M;
    Cancer; 2011 Sep; 117(18):4238-46. PubMed ID: 21387283
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.
    Melko M; Douguet D; Bensaid M; Zongaro S; Verheggen C; Gecz J; Bardoni B
    Hum Mol Genet; 2011 May; 20(10):1873-85. PubMed ID: 21330300
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells.
    Kruse U; Pallasch CP; Bantscheff M; Eberhard D; Frenzel L; Ghidelli S; Maier SK; Werner T; Wendtner CM; Drewes G
    Leukemia; 2011 Jan; 25(1):89-100. PubMed ID: 20944678
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
    Monroe SC; Jo SY; Sanders DS; Basrur V; Elenitoba-Johnson KS; Slany RK; Hess JL
    Exp Hematol; 2011 Jan; 39(1):77-86.e1-5. PubMed ID: 20854876
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Activation of Ras-dependent Elk-1 activity by MLL-AF4 family fusion oncoproteins.
    Ng MH; Ng RK; Kong CT; Jin DY; Chan LC
    Exp Hematol; 2010 Jun; 38(6):481-8. PubMed ID: 20362031
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort.
    Mulrooney DA; Yeazel MW; Kawashima T; Mertens AC; Mitby P; Stovall M; Donaldson SS; Green DM; Sklar CA; Robison LL; Leisenring WM
    BMJ; 2009 Dec; 339():b4606. PubMed ID: 19996459
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The robotic mouse: understanding the role of AF4, a cofactor of transcriptional elongation and chromatin remodelling, in purkinje cell function.
    Bitoun E; Davies KE
    Cerebellum; 2009 Sep; 8(3):175-83. PubMed ID: 19340490
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Panhandle PCR approaches to cloning MLL genomic breakpoint junctions and fusion transcript sequences.
    Robinson BW; Felix CA
    Methods Mol Biol; 2009; 538():85-114. PubMed ID: 19277575
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Twenty-five-year follow-up among survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study.
    Mody R; Li S; Dover DC; Sallan S; Leisenring W; Oeffinger KC; Yasui Y; Robison LL; Neglia JP
    Blood; 2008 Jun; 111(12):5515-23. PubMed ID: 18334672
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Identification of the novel AML1 fusion partner gene, laf4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA.
    Chinen Y; Taki T; Nishida K; Shimizu D; Okuda T; Yoshida N; Kobayashi C; Koike K; Tsuchida M; Hayashi Y; Taniwaki M
    Oncogene; 2008 Apr; 27(15):2249-56. PubMed ID: 17968322
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification.
    Mueller D; Bach C; Zeisig D; Garcia-Cuellar MP; Monroe S; Sreekumar A; Zhou R; Nesvizhskii A; Chinnaiyan A; Hess JL; Slany RK
    Blood; 2007 Dec; 110(13):4445-54. PubMed ID: 17855633
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. [Real-time PCR array for simultaneous detection of 37 kinds of fusion genes in leukemia].
    Liu HX; Zhu P; Zhang Y; Wang HX; DU JW; Liu J; Gu JY; Ou Y
    Zhonghua Yi Xue Za Zhi; 2007 Feb; 87(8):526-32. PubMed ID: 17459201
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling.
    Bitoun E; Oliver PL; Davies KE
    Hum Mol Genet; 2007 Jan; 16(1):92-106. PubMed ID: 17135274
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The robotic mouse: unravelling the function of AF4 in the cerebellum.
    Bitoun E; Davies KE
    Cerebellum; 2005; 4(4):250-60. PubMed ID: 16321881
    [TBL] [Abstract] [Full Text] [Related]  


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