Terms: = Leukemia AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Treatment
1669 results:
1. On the mechanism of wogonin against acute monocytic leukemia using network pharmacology and experimental validation.
Wang X; Wang Y; Chen J; Wang Q; Liu Z; Yin Y; Yang T; Shen T; Sa Y
Sci Rep; 2024 May; 14(1):10114. PubMed ID: 38698063
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2. Regulation of Hypoxia Dependent Reprogramming of Cancer Metabolism: Role of HIF-1 and Its Potential Therapeutic Implications in leukemia.
Pandey S; Singh R; Habib N; Tripathi RM; Kushwaha R; Mahdi AA
Asian Pac J Cancer Prev; 2024 Apr; 25(4):1121-1134. PubMed ID: 38679971
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3. ONC212 enhances YM155 cytotoxicity by triggering SLC35F2 expression and NOXA-dependent MCL1 degradation in acute myeloid leukemia cells.
Chiou JT; Chang LS
Biochem Pharmacol; 2024 Jun; 224():116242. PubMed ID: 38679209
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4. [Effect of Shikonin on Autophagy and Apoptosis of Human Promyelocytic leukemia Cells].
Chen Y; Xie XM; Zhang XL; Zhang XL
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2024 Apr; 32(2):416-421. PubMed ID: 38660845
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5. Inhibition of NRF2 signaling overcomes acquired resistance to arsenic trioxide in FLT3-mutated Acute Myeloid leukemia.
Jebanesan DZP; Illangeswaran RSS; Rajamani BM; Vidhyadharan RT; Das S; Bijukumar NK; Balakrishnan B; Mathews V; Velayudhan SR; Balasubramanian P
Ann Hematol; 2024 Jun; 103(6):1919-1929. PubMed ID: 38630133
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6. Novel PIKfyve/Tubulin Dual-target Inhibitor as a Promising Therapeutic Strategy for B-cell Acute Lymphoblastic leukemia.
Lu Z; Lai Q; Li ZF; Zhong MY; Jiang YL; Feng LY; Zha J; Yao JW; Li Y; Deng XM; Xu B
Curr Med Sci; 2024 Apr; 44(2):298-308. PubMed ID: 38619682
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7. A prognostic model of idiopathic pulmonary fibrosis constructed based on macrophage and mitochondria-related genes.
Bao Y; Yang S; Zhao H; Wang Y; Li K; Liu X; Zhang W; Zhu X
BMC Pulm Med; 2024 Apr; 24(1):176. PubMed ID: 38609879
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8. Discovery of Potent and Selective PI3Kδ Inhibitors for the treatment of Acute Myeloid leukemia.
Tang Y; Zheng Y; Hu X; Zhao H; Cui S
J Med Chem; 2024 Apr; 67(8):6638-6657. PubMed ID: 38577724
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9. PHA-665752's Antigrowth and Proapoptotic Effects on HSC-3 Human Oral Cancer Cells.
Yadav AK; Wang S; Shin YM; Jang BC
Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474118
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10. Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2
Ichikawa T; Suekane A; Nakahata S; Iha H; Shimoda K; Murakami T; Morishita K
Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38474089
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11. Anlotinib Inhibits Cisplatin Resistance in Non-Small-Cell Lung Cancer Cells by Inhibiting MCL-1 Expression via MET/STAT3/akt Pathway.
Wang L; Xu L; Han S; Zhu X
Can Respir J; 2024; 2024():2632014. PubMed ID: 38468814
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12. Gene expression profiling on CML patients with Philadelphia translocation.
Alkhatabi H; Aldahlawi S; Hazzazi MS; Alsolami R; Elaimi A; Almashjary MN; Alserihi R; Alkhatabi HA; Alquthami ME; Daous YM; Bahashwan S; Yasin EB; Barefah A; Alsayes F
Eur Rev Med Pharmacol Sci; 2024 Feb; 28(4):1340-1355. PubMed ID: 38436167
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13. [MiR-217 Targeting PI3K/akt Pathway Enhances Sensitivity of Adriamycin to Acute Myeloid leukemia].
Gan DY; Wu J; Zhou M; Chen W; Jiang W
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2024 Feb; 32(1):39-44. PubMed ID: 38387897
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14. A molecular circuit linking the BCR to the NAD biosynthetic enzyme NAMPT is an actionable target in Richter syndrome.
Messana VG; Fascì A; Vitale N; Micillo M; Rovere M; Pesce NA; Martines C; Efremov DG; Vaisitti T; Deaglio S
Blood Adv; 2024 Apr; 8(8):1920-1933. PubMed ID: 38359376
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15. Licochalcone A induces mitochondria-dependent apoptosis and interacts with venetoclax in acute myeloid leukemia.
Li Y; Zhao M; Lin Y; Jiang X; Jin L; Ye P; Lu Y; Pei R; Jiang L
Eur J Pharmacol; 2024 Apr; 968():176418. PubMed ID: 38350590
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16. IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation.
Yang J; Chen J; Chang J; Sun X; Wei Q; Cai X; Cao P
Cell Commun Signal; 2024 Feb; 22(1):116. PubMed ID: 38347540
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17. SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming.
Xu X; Yu Y; Zhang W; Ma W; He C; Qiu G; Wang X; Liu Q; Zhao M; Xie J; Tao F; Perry JM; Liu Q; Rao S; Kang X; Zhao M; Jiang L
Nat Cell Biol; 2024 Mar; 26(3):464-477. PubMed ID: 38321204
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18. Bioactive triterpenoid compounds of Poria cocos (Schw.) Wolf in the treatment of diabetic ulcers via regulating the PI3K-akt signaling pathway.
Ding X; Li S; Huang H; Shen J; Ding Y; Chen T; Ma L; Liu J; Lai Y; Chen B; Wang Y; Tan Q
J Ethnopharmacol; 2024 May; 325():117812. PubMed ID: 38301984
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19. Carbapenem-resistant Klebsiella pneumoniae bloodstream infections in haematological malignances and hematopoietic stem cell transplantation: Clinical impact of combination therapy in a 10-year Brazilian cohort.
de Souza ILA; Cappellano P; Ferreira DB; Bergamasco MD; das Chagas Neto TC; Kerbauy FR; Baiocchi OCG; Pignatari ACC
PLoS One; 2024; 19(1):e0297161. PubMed ID: 38277372
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20. Long non-coding RNA small nucleolar RNA host gene 29 drives chronic myeloid leukemia progression via microRNA-483-3p/Casitas B-lineage Lymphoma axis-mediated activation of the phosphoinositide 3-kinase/akt pathway.
Feng X; Yang L; Liu X; Liu M; Liu L; Liu J; Luo J
Med Oncol; 2024 Jan; 41(2):60. PubMed ID: 38252204
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