BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7
3649 results:

  • 1. Application and prognostic relevance of CD34 detection in immunophenotyping of pediatric acute B lymphoblastic leukemia.
    Zha W; Yuan Y; Yang T; Zhu LJ; Kong WY; Zhuo JJ
    Eur Rev Med Pharmacol Sci; 2024 May; 28(9):3384-3390. PubMed ID: 38766795
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Structural studies of intrinsically disordered mll-fusion protein AF9 in complex with peptidomimetic inhibitors.
    Yang Y; Ahmad E; Premkumar V; Liu A; Ashikur Rahman SM; Nikolovska-Coleska Z
    Protein Sci; 2024 Jun; 33(6):e5019. PubMed ID: 38747396
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of mll-rearranged cancer cells to WDR5 WIN site inhibition.
    Howard GC; Wang J; Rose KL; Jones C; Patel P; Tsui T; Florian AC; Vlach L; Lorey SL; Grieb BC; Smith BN; Slota MJ; Reynolds EM; Goswami S; Savona MR; Mason FM; Lee T; Fesik S; Liu Q; Tansey WP
    Elife; 2024 Apr; 12():. PubMed ID: 38682900
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A rare kmt2a::CBL transcript in an acute monoblastic leukemia patient with an unfavorable outcome.
    Yu J; Song F; Zhang M; Xiao P; Feng J; Hong R; Hu Y; Huang H; Wei G
    Mol Biol Rep; 2024 Apr; 51(1):561. PubMed ID: 38643442
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Infant Acute Lymphoblastic leukemia-New Therapeutic Opportunities.
    Kulczycka M; Derlatka K; Tasior J; Sygacz M; Lejman M; Zawitkowska J
    Int J Mol Sci; 2024 Mar; 25(7):. PubMed ID: 38612531
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Terminal deoxynucleotidyl transferase expression in different subtypes of childhood B-cell acute lymphoblastic leukemia.
    Yu CH; Su YH; Jou ST; Lu MY; Lin CY; Lin KH; Chang HH; Chou SW; Huang YH; Lin DT; Lin SW; Chen HY; Chang YH; Yang YL
    Pathol Res Pract; 2024 Apr; 256():155287. PubMed ID: 38579576
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Impact of mll::AF9 Gene Rearrangement on Survival of Acute Myeloid Leukaemia Patients: An Insight into Pakistani Population.
    Tariq M; Shahab S; Saeed JR; Hussain Z; Zaidi U; Farzana T; Ahmad S
    J Coll Physicians Surg Pak; 2024 Apr; 34(4):424-428. PubMed ID: 38576284
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. A complex interplay of intra- and extracellular factors regulates the outcome of fetal- and adult-derived mll-rearranged leukemia.
    Jassinskaja M; Ghosh S; Watral J; Davoudi M; Claesson Stern M; Daher U; Eldeeb M; Zhang Q; Bryder D; Hansson J
    Leukemia; 2024 May; 38(5):1115-1130. PubMed ID: 38555405
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Extracellular matrix protein 1 (ECM1) is a potential biomarker in B cell acute lymphoblastic leukemia.
    Wu LX; Zhao MY; Yan N; Zhou YL; Cao LM; Qin YZ; Jiang Q; Xu LP; Zhang XH; Huang XJ; Jiang H; Ruan GR
    Clin Exp Med; 2024 Mar; 24(1):56. PubMed ID: 38546916
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. [Multicenter evaluation of minimal residual disease monitoring in early induction therapy for treatment of childhood acute lymphoblastic leukemia].
    Wu XJ; Liao N; Mai HR; Li XY; Wan WQ; Yang LH; Huang LB; Luo XQ; Tian C; Chen QW; Long XJ; He YY; Wang Y; Li ZG; Xu HG
    Zhonghua Er Ke Za Zhi; 2024 Mar; 62(4):337-344. PubMed ID: 38527504
    [No Abstract]    [Full Text] [Related]  

  • 11. Raman spectroscopy can recognize the kmt2a rearrangement as a distinct subtype of leukemia.
    Leszczenko P; Nowakowska AM; Jakubowska J; Pastorczak A; Zabczynska M; Mlynarski W; Baranska M; Ostrowska K; Majzner K
    Spectrochim Acta A Mol Biomol Spectrosc; 2024 Jun; 314():124173. PubMed ID: 38520957
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Loss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC1.
    Guo T; Wang Y; Sun X; Hou S; Lan Y; Yuan S; Yang S; Zhao F; Chu Y; Ma Y; Cheng T; Yu J; Liu B; Yuan W; Wang X
    Oncogene; 2024 May; 43(19):1476-1487. PubMed ID: 38514854
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Application of droplet digital PCR in minimal residual disease monitoring of rare fusion transcripts and mutations in haematological malignancies.
    Ip BBK; Wong ATC; Law JHY; Au CH; Ma SY; Chim JCS; Liang RHS; Leung AYH; Wan TSK; Ma ESK
    Sci Rep; 2024 Mar; 14(1):6400. PubMed ID: 38493200
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Regulation of HOX gene expression in AML.
    Khan I; Amin MA; Eklund EA; Gartel AL
    Blood Cancer J; 2024 Mar; 14(1):42. PubMed ID: 38453907
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Bahcc1 is critical for the aberrant epigenetic program in a mouse model of mll-ENL-mediated leukemia.
    Nakamura A; Masuya M; Shinmei M; Tawara I; Nosaka T; Ono R
    Blood Adv; 2024 May; 8(9):2193-2206. PubMed ID: 38452334
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. High-dose methotrexate pharmacokinetics and its impact on prognosis of paediatric acute lymphoblastic leukaemia patients: A population pharmacokinetic study.
    Chen X; Li J; Yu L; Hu W; Cai J; Wang Z; Chen C; Zhang X; Xie Y; Wu K; Mo Y; Chen J; Shen S
    Br J Haematol; 2024 Apr; 204(4):1354-1366. PubMed ID: 38432257
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Ferritin-mediated mitochondrial iron homeostasis is essential for the survival of hematopoietic stem cells and leukemic stem cells.
    Yi W; Zhang J; Huang Y; Zhan Q; Zou M; Cheng X; Zhang X; Yin Z; Tao S; Cheng H; Wang F; Guo J; Ju Z; Chen Z
    Leukemia; 2024 May; 38(5):1003-1018. PubMed ID: 38402368
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Discovery of novel pyrrolo[2,3-d]pyrimidines as potent menin-mixed lineage leukemia interaction inhibitors.
    Bai H; Yang Z; Lei H; Wu Y; Liu J; Yuan B; Ma M; Gao L; Zhang SQ; Xin M
    Eur J Med Chem; 2024 Mar; 268():116226. PubMed ID: 38367493
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses.
    Severens JF; Karakaslar EO; van der Reijden BA; Sánchez-López E; van den Berg RR; Halkes CJM; van Balen P; Veelken H; Reinders MJT; Griffioen M; van den Akker EB
    Leukemia; 2024 Apr; 38(4):751-761. PubMed ID: 38360865
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.
    Brouns T; Lux V; Van Belle S; Christ F; Veverka V; Debyser Z
    Cells; 2024 Jan; 13(3):. PubMed ID: 38334618
    [TBL] [Abstract] [Full Text] [Related]  


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