Terms: = Leukemia AND PPM1D, Wip1, 8493, ENSG00000170836, O15297, WIP1, PP2C-DELTA
40 results:
1. The crossroads of cancer therapies and clonal hematopoiesis.
Singh A; Balasubramanian S
Semin Hematol; 2024 Feb; 61(1):16-21. PubMed ID: 38403501
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2. ppm1d modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.
Miller PG; Sperling AS; Mayerhofer C; McConkey ME; Ellegast JM; Da Silva C; Cohen DN; Wang C; Sharda A; Yan N; Saha S; Schluter C; Schechter I; Słabicki M; Sandoval B; Kahn J; Boettcher S; Gibson CJ; Scadden DT; Stegmaier K; Bhatt S; Lindsley RC; Ebert BL
Blood; 2023 Dec; 142(24):2079-2091. PubMed ID: 37595362
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3. Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors.
Franch-Expósito S; Mehine M; Ptashkin RN; Bolton KL; Bandlamudi C; Srinivasan P; Zhang L; Goodell MA; Gedvilaite E; Menghrajani K; Sánchez-Vela P; Mandelker D; Comen E; Norton L; Benayed R; Gao T; Papaemmanuil E; Taylor B; Levine R; Offit K; Stadler Z; Berger MF; Zehir A
JCO Precis Oncol; 2023 Aug; 7():e2300070. PubMed ID: 37561983
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4. Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease.
Gumuser ED; Schuermans A; Cho SMJ; Sporn ZA; Uddin MM; Paruchuri K; Nakao T; Yu Z; Haidermota S; Hornsby W; Weeks LD; Niroula A; Jaiswal S; Libby P; Ebert BL; Bick AG; Natarajan P; Honigberg MC
J Am Coll Cardiol; 2023 May; 81(20):1996-2009. PubMed ID: 37197843
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5. Overlapping features of therapy-related and de novo NPM1-mutated AML.
Othman J; Meggendorfer M; Tiacci E; Thiede C; Schlenk R; Dillon R; Stasik S; Venanzi A; Bertoli S; Delabesse E; Dumas PY; Pigneux A; Bidet A; Gilkes AF; Thomas I; Voso MT; Rambaldi A; Brunetti L; Perriello VM; Andresen V; Gjertsen BT; Martelli MP; Récher C; Röllig C; Bornhäuser M; Serve H; Müller-Tidow C; Baldus CD; Haferlach T; Russell N; Falini B
Blood; 2023 Apr; 141(15):1846-1857. PubMed ID: 36508705
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6. Clonal Hematopoiesis Is Associated with Increased Risk of Severe Neurotoxicity in Axicabtagene Ciloleucel Therapy of Large B-Cell Lymphoma.
Saini NY; Swoboda DM; Greenbaum U; Ma J; Patel RD; Devashish K; Das K; Tanner MR; Strati P; Nair R; Fayad L; Ahmed S; Lee HJ; Iyer SP; Steiner R; Jain N; Nastoupil L; Loghavi S; Tang G; Bassett RL; Jain P; Wang M; Westin JR; Green MR; Sallman DA; Padron E; Davila ML; Locke FL; Champlin RE; Garcia-Manero G; Shpall EJ; Kebriaei P; Flowers CR; Jain MD; Wang F; Futreal AP; Gillis N; Neelapu SS; Takahashi K
Blood Cancer Discov; 2022 Sep; 3(5):385-393. PubMed ID: 35533245
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7. A high prevalence of myeloid malignancies in progeria with Werner syndrome is associated with p53 insufficiency.
Kato H; Maezawa Y; Nishijima D; Iwamoto E; Takeda J; Kanamori T; Yamaga M; Mishina T; Takeda Y; Izumi S; Hino Y; Nishi H; Ishiko J; Takeuchi M; Kaneko H; Koshizaka M; Mimura N; Kuzuya M; Sakaida E; Takemoto M; Shiraishi Y; Miyano S; Ogawa S; Iwama A; Sanada M; Yokote K
Exp Hematol; 2022 May; 109():11-17. PubMed ID: 35240258
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8. Mutant
Singh A; Mencia-Trinchant N; Griffiths EA; Altahan A; Swaminathan M; Gupta M; Gravina M; Tajammal R; Faber MG; Yan L; Sinha E; Hassane DC; Hayes DN; Guzman ML; Iyer R; Wang ES; Thota S
JCO Precis Oncol; 2022 Jan; 6():e2100309. PubMed ID: 35025619
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9. Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease.
Dawoud AAZ; Gilbert RD; Tapper WJ; Cross NCP
Leukemia; 2022 Feb; 36(2):507-515. PubMed ID: 34413458
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10. Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease.
Marnell CS; Bick A; Natarajan P
J Mol Cell Cardiol; 2021 Dec; 161():98-105. PubMed ID: 34298011
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11. Donor clonal hematopoiesis increases risk of acute graft versus host disease after matched sibling transplantation.
Oran B; Champlin RE; Wang F; Tanaka T; Saliba RM; Al-Atrash G; Garcia-Manero G; Kantarjian H; Cao K; Shpall EJ; Alousi AM; Mehta RS; Popat U; Futreal A; Takahashi K
Leukemia; 2022 Jan; 36(1):257-262. PubMed ID: 34135465
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12. Cancer therapy shapes the fitness landscape of clonal hematopoiesis.
Bolton KL; Ptashkin RN; Gao T; Braunstein L; Devlin SM; Kelly D; Patel M; Berthon A; Syed A; Yabe M; Coombs CC; Caltabellotta NM; Walsh M; Offit K; Stadler Z; Mandelker D; Schulman J; Patel A; Philip J; Bernard E; Gundem G; Ossa JEA; Levine M; Martinez JSM; Farnoud N; Glodzik D; Li S; Robson ME; Lee C; Pharoah PDP; Stopsack KH; Spitzer B; Mantha S; Fagin J; Boucai L; Gibson CJ; Ebert BL; Young AL; Druley T; Takahashi K; Gillis N; Ball M; Padron E; Hyman DM; Baselga J; Norton L; Gardos S; Klimek VM; Scher H; Bajorin D; Paraiso E; Benayed R; Arcila ME; Ladanyi M; Solit DB; Berger MF; Tallman M; Garcia-Closas M; Chatterjee N; Diaz LA; Levine RL; Morton LM; Zehir A; Papaemmanuil E
Nat Genet; 2020 Nov; 52(11):1219-1226. PubMed ID: 33106634
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13. ppm1d Knockdown Suppresses Cell Proliferation, Promotes Cell Apoptosis, and Activates p38 MAPK/p53 Signaling Pathway in Acute Myeloid leukemia.
Li B; Hu J; He D; Chen Q; Liu S; Zhu X; Yu M
Technol Cancer Res Treat; 2020; 19():1533033820942312. PubMed ID: 32691668
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14. Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking.
Dawoud AAZ; Tapper WJ; Cross NCP
Leukemia; 2020 Oct; 34(10):2660-2672. PubMed ID: 32518416
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15. Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: a national population-based cohort study.
Husby S; Favero F; Nielsen C; Sørensen BS; Bæch J; Grell K; Hansen JW; Rodriguez-Gonzalez FG; Haastrup EK; Fischer-Nielsen A; Andersen P; Arboe B; Sækmose SG; Hansen PB; Christiansen I; Clasen-Linde E; Meldgaard L; Ebbesen LH; Segel EK; Josefsson P; Thorsgaard M; El-Galaly TC; Brown P; Weischenfeldt J; Larsen TS; Grønbæk K
Leukemia; 2020 Dec; 34(12):3256-3268. PubMed ID: 32203146
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16. Potentiality of Protein phosphatase Mg
Yu M; Hu J; He D; Chen Q; Liu S; Zhu X; Li B
J Clin Lab Anal; 2020 May; 34(5):e23171. PubMed ID: 31901183
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17. Clonal hematopoiesis: Pre-cancer PLUS.
Silver AJ; Jaiswal S
Adv Cancer Res; 2019; 141():85-128. PubMed ID: 30691686
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18. ppm1d Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Hsu JI; Dayaram T; Tovy A; De Braekeleer E; Jeong M; Wang F; Zhang J; Heffernan TP; Gera S; Kovacs JJ; Marszalek JR; Bristow C; Yan Y; Garcia-Manero G; Kantarjian H; Vassiliou G; Futreal PA; Donehower LA; Takahashi K; Goodell MA
Cell Stem Cell; 2018 Nov; 23(5):700-713.e6. PubMed ID: 30388424
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19. CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.
Bellutti F; Tigan AS; Nebenfuehr S; Dolezal M; Zojer M; Grausenburger R; Hartenberger S; Kollmann S; Doma E; Prchal-Murphy M; Uras IZ; Höllein A; Neuberg DS; Ebert BL; Ringler A; Mueller AC; Loizou JI; Hinds PW; Vogl C; Heller G; Kubicek S; Zuber J; Malumbres M; Farlik M; Villunger A; Kollmann K; Sexl V
Cancer Discov; 2018 Jul; 8(7):884-897. PubMed ID: 29899063
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20. Long-term survival after childhood acute lymphoblastic leukaemia: population-based trends in cure and relapse by clinical characteristics.
Smith L; Glaser AW; Kinsey SE; Greenwood DC; Chilton L; Moorman AV; Feltbower RG
Br J Haematol; 2018 Sep; 182(6):851-858. PubMed ID: 29808915
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