Terms: = Leukemia AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
45 results:
1. Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review.
Gomes AR; Varela CL; Pires AS; Tavares-da-Silva EJ; Roleira FMF
Bioorg Chem; 2023 Sep; 138():106600. PubMed ID: 37209561
[TBL] [Abstract] [Full Text] [Related]
2. Diallyl disulfide downregulating RhoGDI2 induces differentiation and inhibit invasion via the rac1/Pak1/LIMK1 pathway in human leukemia HL-60 cells.
Hui T; Yiling J; Guangqun C; Ran L; Hui L; Lan Y; Jie H; Su Q
Environ Toxicol; 2023 May; 38(5):1063-1077. PubMed ID: 36793247
[TBL] [Abstract] [Full Text] [Related]
3. Rac GTPases in acute myeloid leukemia cells: Expression profile and biological effects of pharmacological inhibition.
Ramos DFV; Mancuso RI; Contieri B; Duarte A; Paiva L; de Melo Carrilho J; Saad STO; Lazarini M
Toxicol Appl Pharmacol; 2022 May; 442():115990. PubMed ID: 35331739
[TBL] [Abstract] [Full Text] [Related]
4. 6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes.
Chen D; Liu Y; Zhang F; You Q; Ma W; Wu J; Wu Z
Microbiol Spectr; 2021 Dec; 9(3):e0064621. PubMed ID: 34730435
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5. Biomarkers for gastrointestinal adverse events related to thiopurine therapy.
Zudeh G; Franca R; Stocco G; Decorti G
World J Gastroenterol; 2021 Oct; 27(38):6348-6356. PubMed ID: 34720526
[TBL] [Abstract] [Full Text] [Related]
6. Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia.
Garitano-Trojaola A; Sancho A; Götz R; Eiring P; Walz S; Jetani H; Gil-Pulido J; Da Via MC; Teufel E; Rhodes N; Haertle L; Arellano-Viera E; Tibes R; Rosenwald A; Rasche L; Hudecek M; Sauer M; Groll J; Einsele H; Kraus S; Kortüm MK
Commun Biol; 2021 Jun; 4(1):799. PubMed ID: 34172833
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7. TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with rac1.
Pang Y; Zhao Y; Wang Y; Wang X; Wang R; Liu N; Li P; Ji M; Ye J; Sun T; Li J; Ma D; Lu F; Ji C
J Exp Clin Cancer Res; 2020 Aug; 39(1):158. PubMed ID: 32795319
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8. Cell adhesion to collagen promotes leukemia resistance to doxorubicin by reducing DNA damage through the inhibition of rac1 activation.
Naci D; Berrazouane S; Barabé F; Aoudjit F
Sci Rep; 2019 Dec; 9(1):19455. PubMed ID: 31857649
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9. FLT3-ITD cooperates with rac1 to modulate the sensitivity of leukemic cells to chemotherapeutic agents via regulation of DNA repair pathways.
Wu M; Li L; Hamaker M; Small D; Duffield AS
Haematologica; 2019 Dec; 104(12):2418-2428. PubMed ID: 30975911
[TBL] [Abstract] [Full Text] [Related]
10. Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting.
Karvonen H; Perttilä R; Niininen W; Hautanen V; Barker H; Murumägi A; Heckman CA; Ungureanu D
Oncogene; 2019 Apr; 38(17):3288-3300. PubMed ID: 30631148
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11. [Effects of Tcd A on Rho GTPases and the Cytoskeleton of leukemia Cell Line K562].
Zhao L; Chen C; Li M; Zhang H; Liu B; Fu SW; Xi YM
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2018 Oct; 26(5):1330-1335. PubMed ID: 30295246
[TBL] [Abstract] [Full Text] [Related]
12. The role of the oncogenic Rab35 in cancer invasion, metastasis, and immune evasion, especially in leukemia.
Villagomez FR; Medina-Contreras O; Cerna-Cortes JF; Patino-Lopez G
Small GTPases; 2020 Sep; 11(5):334-345. PubMed ID: 29781368
[TBL] [Abstract] [Full Text] [Related]
13. Long noncoding RNA UCA1 promotes cell proliferation, migration and invasion of human leukemia cells via sponging miR-126.
Sun MD; Zheng YQ; Wang LP; Zhao HT; Yang S
Eur Rev Med Pharmacol Sci; 2018 Apr; 22(8):2233-2245. PubMed ID: 29762824
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14. Wnt5a induces ROR1 to associate with 14-3-3ζ for enhanced chemotaxis and proliferation of chronic lymphocytic leukemia cells.
Yu J; Chen L; Chen Y; Hasan MK; Ghia EM; Zhang L; Wu R; Rassenti LZ; Widhopf GF; Shen Z; Briggs SP; Kipps TJ
Leukemia; 2017 Dec; 31(12):2608-2614. PubMed ID: 28465528
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15. Cirmtuzumab inhibits Wnt5a-induced rac1 activation in chronic lymphocytic leukemia treated with ibrutinib.
Yu J; Chen L; Cui B; Wu C; Choi MY; Chen Y; Zhang L; Rassenti LZ; Widhopf Ii GF; Kipps TJ
Leukemia; 2017 Jun; 31(6):1333-1339. PubMed ID: 27904138
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16. Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer.
Wang K; Gao W; Dou Q; Chen H; Li Q; Nice EC; Huang C
Autophagy; 2016 Dec; 12(12):2498-2499. PubMed ID: 27657889
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17. Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.
Yu J; Chen L; Cui B; Widhopf GF; Shen Z; Wu R; Zhang L; Zhang S; Briggs SP; Kipps TJ
J Clin Invest; 2016 Feb; 126(2):585-98. PubMed ID: 26690702
[TBL] [Abstract] [Full Text] [Related]
18. A ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway Compounds.
Thowfeik FS; AbdulSalam SF; Wunderlich M; Wyder M; Greis KD; Kadekaro AL; Mulloy JC; Merino EJ
Chembiochem; 2015 Nov; 16(17):2513-21. PubMed ID: 26419938
[TBL] [Abstract] [Full Text] [Related]
19. Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2.
Capala ME; Maat H; Bonardi F; van den Boom V; Kuipers J; Vellenga E; Giepmans BN; Schuringa JJ
PLoS One; 2015; 10(5):e0128585. PubMed ID: 26016997
[TBL] [Abstract] [Full Text] [Related]
20. ABL tyrosine kinase inhibition variable effects on the invasive properties of different triple negative breast cancer cell lines.
Chevalier C; Cannet A; Descamps S; Sirvent A; Simon V; Roche S; Benistant C
PLoS One; 2015; 10(3):e0118854. PubMed ID: 25803821
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