BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Lung cancer AND JAK2, ENSG00000096968, O60674, JTK10, 3717
284 results:

  • 1. Determinants of mosaic chromosomal alteration fitness.
    Pershad Y; Mack T; Poisner H; Jakubek YA; Stilp AM; Mitchell BD; Lewis JP; Boerwinkle E; Loos RJF; Chami N; Wang Z; Barnes K; Pankratz N; Fornage M; Redline S; Psaty BM; Bis JC; Shojaie A; Silverman EK; Cho MH; Yun JH; DeMeo D; Levy D; Johnson AD; Mathias RA; Taub MA; Arnett D; North KE; Raffield LM; Carson AP; Doyle MF; Rich SS; Rotter JI; Guo X; Cox NJ; Roden DM; Franceschini N; Desai P; Reiner AP; Auer PL; Scheet PA; Jaiswal S; Weinstock JS; Bick AG
    Nat Commun; 2024 May; 15(1):3800. PubMed ID: 38714703
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Metochalcone induces senescence-associated secretory phenotype via jak2/STAT3 pathway in breast cancer.
    Zhou J; Wan F; Xiao B; Li X; Peng C; Peng FU
    Oncol Res; 2024; 32(5):943-953. PubMed ID: 38686052
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating jak2 and MCM8.
    Zhou L; Le MNU; Du Y; Chen X; Jin M; Xiang H; Xia LE; Zhou J; He J; Ning Y
    Gene; 2024 Jul; 916():148449. PubMed ID: 38588931
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. IL6-STAT3-C/EBPβ-IL6 positive feedback loop in tumor-associated macrophages promotes the EMT and metastasis of lung adenocarcinoma.
    Hu Z; Sui Q; Jin X; Shan G; Huang Y; Yi Y; Zeng D; Zhao M; Zhan C; Wang Q; Lin Z; Lu T; Chen Z
    J Exp Clin Cancer Res; 2024 Feb; 43(1):63. PubMed ID: 38424624
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. A coumarin-furoxan hybrid as novel nitric oxide donor induced cell apoptosis and ferroptosis in NSCLC by promoting S-nitrosylation of STAT3 and negative regulation of jak2-STAT3 pathway.
    Cao F; Li M; Wang W; Yi Y; Chen Y; Liu H
    Biochem Pharmacol; 2024 Apr; 222():116068. PubMed ID: 38387529
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Farnesoid X receptor promotes non-small cell lung cancer metastasis by activating jak2/STAT3 signaling via transactivation of IL-6ST and IL-6 genes.
    Jin X; Shang B; Wang J; Sun J; Li J; Liang B; Wang X; Su L; You W; Jiang S
    Cell Death Dis; 2024 Feb; 15(2):148. PubMed ID: 38360812
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Dynamic phenotypic reprogramming and chemoresistance induced by lung fibroblasts in small cell lung cancer.
    Lu Y; Li H; Zhao P; Tian L; Liu Y; Sun X; Cheng Y
    Sci Rep; 2024 Feb; 14(1):2884. PubMed ID: 38311608
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. jak2 Loss Arising From Tumor-Spread-Through-Air-Spaces (STAS) Promotes Tumor Progression by Suppressing CD8+ T Cells in lung Adenocarcinoma: A Machine Learning Approach.
    Choi S; Kim HS; Min KW; Noh YK; Lee JY; Moon JY; Jung US; Kwon MJ; Kim DH; Son BK; Pyo JS; Ro SK
    J Korean Med Sci; 2024 Jan; 39(2):e16. PubMed ID: 38225784
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Protein tyrosine phosphatase PTPRO represses lung adenocarcinoma progression by inducing mitochondria-dependent apoptosis and restraining tumor metastasis.
    Dai Y; Shi S; Liu H; Zhou H; Ding W; Liu C; Jin L; Xie W; Kong H; Zhang Q
    Cell Death Dis; 2024 Jan; 15(1):11. PubMed ID: 38182570
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient.
    Zhang S; Yan J; He L; Jiang Z; Jiang H
    Cancer Gene Ther; 2024 Mar; 31(3):484-494. PubMed ID: 38135698
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Hypoxia Potentiated lung cancer Cell Migration and Invasion by up-regulating HIF1α/jak2/STAT3 Axis and Activating MMP13 Transcription.
    Cheng X; Liang D; Li X; Deng C; Ye M; Yang J; Liu Y; Wu K; Wu J; Tian P
    Cell Biochem Biophys; 2024 Mar; 82(1):259-270. PubMed ID: 38129709
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. SOCS2 inhibits hepatoblastoma metastasis via downregulation of the jak2/STAT5 signal pathway.
    Lv Y; Xie X; Zou G; Kong M; Yang J; Chen J; Xiang B
    Sci Rep; 2023 Dec; 13(1):21814. PubMed ID: 38071211
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Anticancer Effects of 6-Gingerol through Downregulating Iron Transport and PD-L1 Expression in Non-Small Cell lung cancer Cells.
    Kang DY; Park S; Song KS; Bae SW; Lee JS; Jang KJ; Park YM
    Cells; 2023 Nov; 12(22):. PubMed ID: 37998363
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Identifying survival of pan-cancer patients under immunotherapy using genomic mutation signature with large sample cohorts.
    Zhang L; Wang Y; Wang L; Wang M; Li S; He J; Ji J; Li K; Cao L
    J Mol Med (Berl); 2024 Jan; 102(1):69-79. PubMed ID: 37978056
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk.
    Tobias DK; Manning AK; Wessel J; Raghavan S; Westerman KE; Bick AG; Dicorpo D; Whitsel EA; Collins J; Correa A; Cupples LA; Dupuis J; Goodarzi MO; Guo X; Howard B; Lange LA; Liu S; Raffield LM; Reiner AP; Rich SS; Taylor KD; Tinker L; Wilson JG; Wu P; Carson AP; Vasan RS; Fornage M; Psaty BM; Kooperberg C; Rotter JI; Meigs J; Manson JE;
    Diabetes Care; 2023 Nov; 46(11):1978-1985. PubMed ID: 37756531
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in jak2V617F myeloproliferative neoplasms.
    Guy A; Garcia G; Gourdou-Latyszenok V; Wolff-Trombini L; Josserand L; Kimmerlin Q; Favre S; Kilani B; Marty C; Boulaftali Y; Labrouche-Colomer S; Mansier O; James C
    J Thromb Haemost; 2024 Jan; 22(1):172-187. PubMed ID: 37678548
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. FOXA1 prolongs S phase and promotes cancer progression in non-small cell lung cancer through upregulation of CDC5L and activation of the ERK1/2 and jak2 pathways.
    Chen G; Wei RS; Ma J; Li XH; Feng L; Yu JR
    Kaohsiung J Med Sci; 2023 Nov; 39(11):1077-1086. PubMed ID: 37658700
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.
    Zhang C; Sun Q; Zhao J; Jiang N; Hao Y; Luo J; Karim S; Wu L; de Perrot M; Peng C; Zhao X
    Mol Carcinog; 2023 Dec; 62(12):1888-1901. PubMed ID: 37642305
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
    Yu Z; Fidler TP; Ruan Y; Vlasschaert C; Nakao T; Uddin MM; Mack T; Niroula A; Heimlich JB; Zekavat SM; Gibson CJ; Griffin GK; Wang Y; Peloso GM; Heard-Costa N; Levy D; Vasan RS; Aguet F; Ardlie KG; Taylor KD; Rich SS; Rotter JI; Libby P; Jaiswal S; Ebert BL; Bick AG; Tall AR; Natarajan P
    J Clin Invest; 2023 Sep; 133(18):. PubMed ID: 37498674
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer.
    Jia T; Miao R; Zhang J; Zhu H; Zhang C; Zeng L; Zhao Y; Cheng W; Shao J
    Bioorg Med Chem; 2023 Aug; 91():117384. PubMed ID: 37356356
    [TBL] [Abstract] [Full Text] [Related]  


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