BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Ovarian cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Treatment
944 results:

  • 1. Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis.
    Wang M; Yuan C; Wu Z; Xu M; Chen Z; Yao J; Que Z; Tian J; Leung EL; Wang Z
    Int J Biol Sci; 2024; 20(7):2454-2475. PubMed ID: 38725854
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Tumour-derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13-CCR2-M2 macrophage axis.
    Liang H; Geng S; Wang Y; Fang Q; Xin Y; Li Y
    J Cell Mol Med; 2024 May; 28(9):e18315. PubMed ID: 38680032
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Exploring the therapeutic potential of tonic Chinese herbal medicine for gynecological disorders: An updated review.
    He Q; Wan S; Jiang M; Li W; Zhang Y; Zhang L; Wu M; Lin J; Zou L; Hu Y
    J Ethnopharmacol; 2024 Jul; 329():118144. PubMed ID: 38583732
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A novel SIK2 inhibitor SIC-19 exhibits synthetic lethality with PARP inhibitors in ovarian cancer.
    Wang F; Yu X; Qian J; Cao Y; Dong S; Zhan S; Lu Z; Bast RC; Song Q; Chen Y; Zhang Y; Zhou J
    Drug Resist Updat; 2024 May; 74():101077. PubMed ID: 38518726
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures.
    Rausio H; Cervera A; Heuser VD; West G; Oikkonen J; Pianfetti E; Lovino M; Ficarra E; Taimen P; Hynninen J; Lehtonen R; Hautaniemi S; Carpén O; Huhtinen K
    Neoplasia; 2024 May; 51():100987. PubMed ID: 38489912
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. akting on R Loops Makes for an ATractive Target in ovarian cancer Therapy.
    Ramanarayanan V; Oberdoerffer P
    Cancer Res; 2024 Mar; 84(6):793-795. PubMed ID: 38486481
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. TOP2A modulates signaling via the akt/mTOR pathway to promote ovarian cancer cell proliferation.
    Zhang K; Zheng X; Sun Y; Feng X; Wu X; Liu W; Gao C; Yan Y; Tian W; Wang Y
    Cancer Biol Ther; 2024 Dec; 25(1):2325126. PubMed ID: 38445610
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Periostin's role in uterine leiomyoma development: a mini-review on the potential periostin poses as a pharmacological intervention for uterine leiomyoma.
    Kiesler ZG; Hunter MI; Balboula AZ; Patterson AL
    Arch Gynecol Obstet; 2024 May; 309(5):1825-1831. PubMed ID: 38441600
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer.
    Kudo K; Greer YE; Yoshida T; Harrington BS; Korrapati S; Shibuya Y; Henegar L; Kopp JB; Fujii T; Lipkowitz S; Annunziata CM
    Cancer Gene Ther; 2024 May; 31(5):721-735. PubMed ID: 38424218
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Combined inhibition of HER2 and VEGFR synergistically improves therapeutic efficacy via PI3K-akt pathway in advanced ovarian cancer.
    Li W; Zhang K; Wang W; Liu Y; Huang J; Zheng M; Li L; Zhang X; Xu M; Chen G; Wang L; Zhang S
    J Exp Clin Cancer Res; 2024 Feb; 43(1):56. PubMed ID: 38403634
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The miR-1290/OGN axis in ovarian cancer-associated fibroblasts modulates cancer cell proliferation and invasion.
    Jiang B; Xiao S; Zhang S; Xiao F
    J Ovarian Res; 2024 Feb; 17(1):52. PubMed ID: 38402185
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Complexity of the Genetic Background of Oncogenesis in ovarian cancer-Genetic Instability and Clinical Implications.
    Murawski M; Jagodziński A; Bielawska-Pohl A; Klimczak A
    Cells; 2024 Feb; 13(4):. PubMed ID: 38391958
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. VNP20009-Abvec-Igκ-MIIP suppresses ovarian cancer progression by modulating Ras/MEK/ERK signaling pathway.
    Wang Q; Tang Y; Dai A; Li T; Pei Y; Zhang Z; Hu X; Chen T; Chen Q
    Appl Microbiol Biotechnol; 2024 Feb; 108(1):218. PubMed ID: 38372808
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/akt signaling pathway in ovarian cancer.
    Wang H; Liu J; Zhang Z; Peng J; Wang Z; Yang L; Wang X; Hu S; Hong L
    Free Radic Biol Med; 2024 Mar; 214():137-157. PubMed ID: 38364944
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. akt1 interacts with DHX9 to Mitigate R Loop-Induced Replication Stress in ovarian cancer.
    Huang TT; Chiang CY; Nair JR; Wilson KM; Cheng K; Lee JM
    Cancer Res; 2024 Mar; 84(6):887-904. PubMed ID: 38241710
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Comprehensive Analysis of MICALL2 Reveals Its Potential Roles in EGFR Stabilization and ovarian cancer Cell Invasion.
    Xia T; Ye F; Zhao W; Min P; Qi C; Wang Q; Zhao M; Zhang Y; Du J
    Int J Mol Sci; 2023 Dec; 25(1):. PubMed ID: 38203692
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Pan-EGFR Inhibitor Dacomitinib Resensitizes Paclitaxel and Induces Apoptosis via Elevating Intracellular ROS Levels in ovarian cancer SKOV3-TR Cells.
    Lim YJ; Kim HS; Bae S; So KA; Kim TJ; Lee JH
    Molecules; 2024 Jan; 29(1):. PubMed ID: 38202856
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. PAX2 is regulated by estrogen/progesterone through promoter methylation in endometrioid adenocarcinoma and has an important role in carcinogenesis via the akt/mTOR signaling pathway.
    Chen H; Li L; Liu H; Qin P; Chen R; Liu S; Xiong H; Li Y; Yang Z; Xie M; Yang H; Jiang Q
    J Pathol; 2024 Apr; 262(4):467-479. PubMed ID: 38185904
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Selectively targeting BCL6 using a small molecule inhibitor is a potential therapeutic strategy for ovarian cancer.
    Wu M; Xie J; Xing Y; Zhang L; Chen H; Tang B; Zhou M; Lv S; Huang D; Jian S; Zhou C; Liu M; Guo W; Chen Y; Yi Z
    Int J Biol Sci; 2024; 20(2):486-501. PubMed ID: 38169532
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. MK8722 initiates early-stage autophagy while inhibiting late-stage autophagy via FASN-dependent reprogramming of lipid metabolism.
    Wang L; Zhu H; Shi Z; Chen B; Huang H; Lin G; Li J; Yu H; Xu S; Chen G; Ou R; Dai C
    Theranostics; 2024; 14(1):75-95. PubMed ID: 38164137
    [No Abstract]    [Full Text] [Related]  


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