Title: Cerebral edema associated with Gliadel wafers: two case studies. Author: Weber EL, Goebel EA. Journal: Neuro Oncol; 2005 Jan; 7(1):84-9. PubMed ID: 15701285. Abstract: While the introduction of carmustine wafers (Gliadel wafers) into the tumor resection cavity has been shown to be a beneficial therapy for malignant glioma, it is recognized that clinically significant cerebral edema is a potential adverse effect. Following are two clinical case reports demonstrating profound cerebral edema associated with implantation of Gliadel wafers. As a result, one of these individuals had premature death. A brief literature review is provided to assist in explaining the mechanisms by which clinically significant cerebral edema may develop.[Abstract] [Full Text] [Related] [New Search]
