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  • Title: Treatment of post-electroconvulsive therapy delirium and agitation with donepezil.
    Author: Logan CJ, Stewart JT.
    Journal: J ECT; 2007 Mar; 23(1):28-9. PubMed ID: 17435571.
    Abstract:
    Delirium and agitation are commonly encountered after administration of electroconvulsive therapy (ECT). Management is generally fairly straightforward, although some patients may have a severe, prolonged, or refractory course. We recently cared for a 65-year-old man who consistently developed severe and very prolonged post-ECT delirium that did not respond to typical pharmacological agents; the duration of delirium was dramatically shortened by the addition of donepezil. Cholinesterase inhibitors may have a place in mitigating severe and prolonged post-ECT delirium.
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