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  • Title: [Coherences between the metabolic syndrome, depression, stress and physical activity].
    Author: Neumann NU, Frasch K.
    Journal: Psychiatr Prax; 2009 Apr; 36(3):110-4. PubMed ID: 18924063.
    Abstract:
    OBJECTIVE: Analysis of coherences between metabolic syndrome (MTS) and depression. METHODS: Literature research in Medline. RESULTS: The metabolic syndrome (MTS) is characterized by the coexistence of (abdominal) obesity, type 2 diabetes, hypertension and dyslipidaemia while insulin resistance is one pathophysiological key factor. MTS is a risk factor for the development of depressive disorders and vice versa. MTS (usually) and depression (quite often) are associated with insulin resistance, type 2 diabetes, obesity and increased risk of myocardial infarction. Environmental factors like lack of physical exercise, malnutrition and stress may play an important role in the genesis of both disorders. CONCLUSIONS: On the one hand, physical activity has positive effects on all elements of MTS, especially insulin resistance, on the other hand, mild antidepressant effects of physical activity have been demonstrated. The results of animal experiments refer to the essential relevance of physical activity concerning "brain health", specifically with respect to hippocampal neuroplasticity.
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