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  • Title: [Splenic abscess caused by Coxiella burnetti in the absence of endocarditis].
    Author: Cathébras P, Brouqui P, Philippe P, Raoult D, Rousset H.
    Journal: Rev Med Interne; 1998 Oct; 19(10):740-2. PubMed ID: 9827448.
    Abstract:
    INTRODUCTION: The most frequent clinical expression of chronic Q fever is culture-negative endocarditis. Other localizations are rare. EXEGESIS: We report a documented case of chronic Q fever that occurred in a 47-year-old immunocompetent man and was associated with spleen abscess, in the absence of detectable endocarditis. The spleen abscess was a complication of either a preexisting cyst or a calcified hematoma. Splenic infection with Coxiella burnetii was documented with cultures, polymerase chain reaction and immunohistochemistry. The outcome was favorable after splenectomy and a 21-month antibiotherapy. CONCLUSION: Chronic Q fever may develop in the absence of endocarditis, when a preexisting vascular lesion such as aortic aneurysm exists. A splenic cyst may have played a similar role for this patient.
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