BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 10021419)

  • 1. Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides.
    Marx A; Spichty M; Amacker M; Schwitter U; Hübscher U; Bickle TA; Maga G; Giese B
    Chem Biol; 1999 Feb; 6(2):111-6. PubMed ID: 10021419
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
    Najmudin S; Coté ML; Sun D; Yohannan S; Montano SP; Gu J; Georgiadis MM
    J Mol Biol; 2000 Feb; 296(2):613-32. PubMed ID: 10669612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutational analysis of Lys65 of HIV-1 reverse transcriptase.
    Sluis-Cremer N; Arion D; Kaushik N; Lim H; Parniak MA
    Biochem J; 2000 May; 348 Pt 1(Pt 1):77-82. PubMed ID: 10794716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of interactions of DNA polymerase beta and reverse transcriptases of human immunodeficiency and mouse leukemia viruses with dNTP analogs containing a modified sugar residue.
    Lebedeva NA; Seredina TA; Silnikov VN; Abramova TV; Levina AS; Khodyreva SN; Rechkunova NI; Lavrik OI
    Biochemistry (Mosc); 2005 Jan; 70(1):1-7. PubMed ID: 15701045
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase.
    Tachedjian G; Radzio J; Sluis-Cremer N
    Proteins; 2005 Jul; 60(1):5-13. PubMed ID: 15852304
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p66 Trp24 and Phe61 are essential for accurate association of HIV-1 reverse transcriptase with primer/template.
    Agopian A; Depollier J; Lionne C; Divita G
    J Mol Biol; 2007 Oct; 373(1):127-40. PubMed ID: 17804012
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Refined model for primer/template binding by HIV-1 reverse transcriptase: pre-steady-state kinetic analyses of primer/template binding and nucleotide incorporation events distinguish between different binding modes depending on the nature of the nucleic acid substrate.
    Wöhrl BM; Krebs R; Goody RS; Restle T
    J Mol Biol; 1999 Sep; 292(2):333-44. PubMed ID: 10493879
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanistic insights into the role of Val75 of HIV-1 reverse transcriptase in misinsertion and mispair extension fidelity of DNA synthesis.
    Matamoros T; Kim B; Menéndez-Arias L
    J Mol Biol; 2008 Feb; 375(5):1234-48. PubMed ID: 18155043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenesis of Gln294 of the reverse transcriptase of human immunodeficiency virus type-2 and its effects on the ribonuclease H activity.
    Bochner R; Duvshani A; Adir N; Hizi A
    FEBS Lett; 2008 Aug; 582(18):2799-805. PubMed ID: 18625228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase.
    Feng JY; Anderson KS
    Biochemistry; 1999 Jul; 38(29):9440-8. PubMed ID: 10413520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer.
    Peletskaya EN; Boyer PL; Kogon AA; Clark P; Kroth H; Sayer JM; Jerina DM; Hughes SH
    J Virol; 2001 Oct; 75(19):9435-45. PubMed ID: 11533206
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides.
    Vastmans K; Froeyen M; Kerremans L; Pochet S; Herdewijn P
    Nucleic Acids Res; 2001 Aug; 29(15):3154-63. PubMed ID: 11470872
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Explanation of pre-steady-state kinetics and decreased burst amplitude of HIV-1 reverse transcriptase at sites of modified DNA bases with an additional, nonproductive enzyme-DNA-nucleotide complex.
    Furge LL; Guengerich FP
    Biochemistry; 1999 Apr; 38(15):4818-25. PubMed ID: 10200170
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase.
    Gao HQ; Sarafianos SG; Arnold E; Hughes SH
    J Mol Biol; 1999 Dec; 294(5):1097-113. PubMed ID: 10600369
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased thermostability and fidelity of DNA synthesis of wild-type and mutant HIV-1 group O reverse transcriptases.
    Alvarez M; Matamoros T; Menéndez-Arias L
    J Mol Biol; 2009 Oct; 392(4):872-84. PubMed ID: 19651140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases.
    Murakami E; Basavapathruni A; Bradley WD; Anderson KS
    Antiviral Res; 2005 Jul; 67(1):10-7. PubMed ID: 15950748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Reverse transcriptase of the human immunodeficiency virus: isolation and substrate specificity].
    Rozovskaia TA; Belogurov AA; Lukin MA; Chernov DN; Kukhanova MK; Bibilashvili RSh
    Mol Biol (Mosk); 1993; 27(3):618-30. PubMed ID: 7686251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
    Gao HQ; Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Mol Biol; 2000 Jul; 300(2):403-18. PubMed ID: 10873473
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Study on steady-state kinetics of nucleotide analogues incorporation by non-gel CE.
    Li W; Cao M; Pei L; Ling X; Li B; Yang Z
    Electrophoresis; 2010 Jan; 31(3):507-11. PubMed ID: 20119962
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis.
    Ray AS; Murakami E; Basavapathruni A; Vaccaro JA; Ulrich D; Chu CK; Schinazi RF; Anderson KS
    Biochemistry; 2003 Jul; 42(29):8831-41. PubMed ID: 12873144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.