104 related articles for article (PubMed ID: 10021922)
21. Binding mode prediction of aplysiatoxin, a potent agonist of protein kinase C, through molecular simulation and structure-activity study on simplified analogs of the receptor-recognition domain.
Ashida Y; Yanagita RC; Takahashi C; Kawanami Y; Irie K
Bioorg Med Chem; 2016 Sep; 24(18):4218-4227. PubMed ID: 27436807
[TBL] [Abstract][Full Text] [Related]
22. Characterization of phorbol ester binding to protein kinase C isotypes.
Dimitrijević SM; Ryves WJ; Parker PJ; Evans FJ
Mol Pharmacol; 1995 Aug; 48(2):259-67. PubMed ID: 7651359
[TBL] [Abstract][Full Text] [Related]
23. Structural insights into the interactions of phorbol ester and bryostatin complexed with protein kinase C: a comparative molecular dynamics simulation study.
Thangsunan P; Tateing S; Hannongbua S; Suree N
J Biomol Struct Dyn; 2016 Jul; 34(7):1561-75. PubMed ID: 26292580
[TBL] [Abstract][Full Text] [Related]
24. Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?
Nacro K; Bienfait B; Lee J; Han KC; Kang JH; Benzaria S; Lewin NE; Bhattacharyya DK; Blumberg PM; Marquez VE
J Med Chem; 2000 Mar; 43(5):921-44. PubMed ID: 10715158
[TBL] [Abstract][Full Text] [Related]
25. Phosphatidylinositol 4,5-bisphosphate competitively inhibits phorbol ester binding to protein kinase C.
Chauhan A; Chauhan VP; Deshmukh DS; Brockerhoff H
Biochemistry; 1989 Jun; 28(12):4952-6. PubMed ID: 2548596
[TBL] [Abstract][Full Text] [Related]
26. Protein kinase C modulators bearing dicarba-CLOSO-dodecaborane as a hydrophobic pharmacophore.
Endo Y; Yoshimi T; Kimura K; Itai A
Bioorg Med Chem Lett; 1999 Sep; 9(17):2561-4. PubMed ID: 10498208
[TBL] [Abstract][Full Text] [Related]
27. [The active structure of tumor promoters].
Endo Y; Itai A; Shudo K; Fujiki H
Gan To Kagaku Ryoho; 1986 Dec; 13(12):3365-75. PubMed ID: 3098181
[TBL] [Abstract][Full Text] [Related]
28. Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V.
Nakagawa Y; Irie K; Ohigashi H; Hayashi H; Wender PA
Bioorg Med Chem Lett; 2000 Sep; 10(18):2087-90. PubMed ID: 10999477
[TBL] [Abstract][Full Text] [Related]
29. Conformationally constrained diacylglycerol (DAG) analogs: 4-C-hydroxyethyl-5-O-acyl-2,3-dideoxy-D-glyceropentono-1,4-lactone analogs as protein kinase C (PKC) ligands.
Lee J; Kim SY; Kang JH; Acs G; Acs P; Blumberg PM; Marquez VE
Eur J Med Chem; 2004 Jan; 39(1):69-77. PubMed ID: 14987835
[TBL] [Abstract][Full Text] [Related]
30. Design, synthesis and glycosidase inhibition studies of novel triazole fused iminocyclitol-δ-lactams.
Santhanam V; Pant P; Jayaram B; Ramesh NG
Org Biomol Chem; 2019 Jan; 17(5):1130-1140. PubMed ID: 30633287
[TBL] [Abstract][Full Text] [Related]
31. Conformationally constrained analogues of diacylglycerol. 11. Ultrapotent protein kinase C ligands based on a chiral 5-disubstituted tetrahydro-2-furanone template.
Lee J; Wang S; Milne GW; Sharma R; Lewin NE; Blumberg PM; Marquez VE
J Med Chem; 1996 Jan; 39(1):29-35. PubMed ID: 8568819
[TBL] [Abstract][Full Text] [Related]
32. The conformations and electrostatic potential maps of phorbol esters, teleocidins and ingenols.
Thomson C; Wilkie J
Carcinogenesis; 1989 Mar; 10(3):531-40. PubMed ID: 2924397
[TBL] [Abstract][Full Text] [Related]
33. An optimized protein kinase C activating diacylglycerol combining high binding affinity (Ki) with reduced lipophilicity (log P).
Nacro K; Sigano DM; Yan S; Nicklaus MC; Pearce LL; Lewin NE; Garfield SH; Blumberg PM; Marquez VE
J Med Chem; 2001 Jun; 44(12):1892-904. PubMed ID: 11384235
[TBL] [Abstract][Full Text] [Related]
34. Ca2+-independent binding of [3H]phorbol dibutyrate to protein kinase C is supported by protamine and other polycations.
Thompson NT; Bonser RW; Hodson HF; Garland LG
Biochem J; 1988 Oct; 255(2):417-22. PubMed ID: 3202826
[TBL] [Abstract][Full Text] [Related]
35. NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions.
Xu RX; Pawelczyk T; Xia TH; Brown SC
Biochemistry; 1997 Sep; 36(35):10709-17. PubMed ID: 9271501
[TBL] [Abstract][Full Text] [Related]
36. Loss of the Phenolic Hydroxyl Group and Aromaticity from the Side Chain of Anti-Proliferative 10-Methyl-aplog-1, a Simplified Analog of Aplysiatoxin, Enhances Its Tumor-Promoting and Proinflammatory Activities.
Hanaki Y; Kikumori M; Tokuda H; Okamura M; Dan S; Adachi N; Saito N; Yanagita RC; Irie K
Molecules; 2017 Apr; 22(4):. PubMed ID: 28406454
[TBL] [Abstract][Full Text] [Related]
37. Binding of [3H]bryostatin 4 to protein kinase C.
Lewin NE; Dell'Aquila ML; Pettit GR; Blumberg PM; Warren BS
Biochem Pharmacol; 1992 May; 43(9):2007-14. PubMed ID: 1596288
[TBL] [Abstract][Full Text] [Related]
38. Functions, Structures, and Engineering of the Teleocidin Biosynthetic Enzymes.
Mori T
Chem Pharm Bull (Tokyo); 2023; 71(3):188-197. PubMed ID: 36858523
[TBL] [Abstract][Full Text] [Related]
39. (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta.
Jirousek MR; Gillig JR; Gonzalez CM; Heath WF; McDonald JH; Neel DA; Rito CJ; Singh U; Stramm LE; Melikian-Badalian A; Baevsky M; Ballas LM; Hall SE; Winneroski LL; Faul MM
J Med Chem; 1996 Jul; 39(14):2664-71. PubMed ID: 8709095
[TBL] [Abstract][Full Text] [Related]
40. Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes.
Kazanietz MG; Areces LB; Bahador A; Mischak H; Goodnight J; Mushinski JF; Blumberg PM
Mol Pharmacol; 1993 Aug; 44(2):298-307. PubMed ID: 8355667
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]