BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 10022754)

  • 1. Deficiency of cytosolic arylamine N-acetylation in the domestic cat and wild felids caused by the presence of a single NAT1-like gene.
    Trepanier LA; Cribb AE; Spielberg SP; Ray K
    Pharmacogenetics; 1998 Apr; 8(2):169-79. PubMed ID: 10022754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytosolic arylamine N-acetyltransferase (NAT) deficiency in the dog and other canids due to an absence of NAT genes.
    Trepanier LA; Ray K; Winand NJ; Spielberg SP; Cribb AE
    Biochem Pharmacol; 1997 Jul; 54(1):73-80. PubMed ID: 9296352
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes.
    Grant DM; Blum M; Beer M; Meyer UA
    Mol Pharmacol; 1991 Feb; 39(2):184-91. PubMed ID: 1996083
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding.
    Laurieri N; Kawamura A; Westwood IM; Varney A; Morris E; Russell AJ; Stanley LA; Sim E
    BMC Pharmacol Toxicol; 2014 Nov; 15():68. PubMed ID: 25432241
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
    Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
    Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
    Hein DW; Doll MA; Rustan TD; Gray K; Feng Y; Ferguson RJ; Grant DM
    Carcinogenesis; 1993 Aug; 14(8):1633-8. PubMed ID: 8353847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human N-acetylation of benzidine: role of NAT1 and NAT2.
    Zenser TV; Lakshmi VM; Rustan TD; Doll MA; Deitz AC; Davis BB; Hein DW
    Cancer Res; 1996 Sep; 56(17):3941-7. PubMed ID: 8752161
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recombinant rat and hamster N-acetyltransferases-1 and -2: relative rates of N-acetylation of arylamines and N,O-acyltransfer with arylhydroxamic acids.
    Jones RF; Land SJ; King CM
    Carcinogenesis; 1996 Aug; 17(8):1729-33. PubMed ID: 8761433
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acetylation of serotonin in the rabbit pineal gland: an N-acetyltransferase with properties distinct from NAT1 and NAT2 is responsible.
    Heim MH; Blum M; Beer M; Meyer UA
    J Neurochem; 1991 Oct; 57(4):1095-9. PubMed ID: 1895098
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of amino acids imparting acceptor substrate selectivity to human arylamine acetyltransferases NAT1 and NAT2.
    Goodfellow GH; Dupret JM; Grant DM
    Biochem J; 2000 May; 348 Pt 1(Pt 1):159-66. PubMed ID: 10794727
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular and Functional Characterization of N-Acetyltransferases NAT1 and NAT2 in Cynomolgus Macaque.
    Uno Y; Murayama N; Yamazaki H
    Chem Res Toxicol; 2018 Nov; 31(11):1269-1276. PubMed ID: 30358977
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
    Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
    Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2.
    Walraven JM; Doll MA; Hein DW
    J Pharmacol Exp Ther; 2006 Oct; 319(1):369-75. PubMed ID: 16829624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-function studies of human arylamine N-acetyltransferases NAT1 and NAT2. Functional analysis of recombinant NAT1/NAT2 chimeras expressed in Escherichia coli.
    Dupret JM; Goodfellow GH; Janezic SA; Grant DM
    J Biol Chem; 1994 Oct; 269(43):26830-5. PubMed ID: 7929420
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2.
    Liu L; Von Vett A; Zhang N; Walters KJ; Wagner CR; Hanna PE
    Chem Res Toxicol; 2007 Sep; 20(9):1300-8. PubMed ID: 17672512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.
    Hein DW; Doll MA; Rustan TD; Gray K; Ferguson RJ; Feng Y
    Toxicol Appl Pharmacol; 1994 Jan; 124(1):16-24. PubMed ID: 8291057
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse.
    Sugamori KS; Brenneman D; Wong S; Gaedigk A; Yu V; Abramovici H; Rozmahel R; Grant DM
    Drug Metab Dispos; 2007 Jul; 35(7):1064-70. PubMed ID: 17403913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic variants of N-acetyltransferases 1 and 2 (NAT1 and NAT2) in cynomolgus and rhesus macaques.
    Uno Y; Murayama N; Yamazaki H
    Biochem Pharmacol; 2020 Jul; 177():113996. PubMed ID: 32339492
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines.
    Liu L; Wagner CR; Hanna PE
    Chem Res Toxicol; 2009 Dec; 22(12):1962-74. PubMed ID: 19842618
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster.
    Hein DW; Doll MA; Xiao GH; Feng Y
    Pharmacogenetics; 2003 Mar; 13(3):159-67. PubMed ID: 12618593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.