BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1180 related articles for article (PubMed ID: 10022898)

  • 1. Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts.
    Stein GH; Drullinger LF; Soulard A; Dulić V
    Mol Cell Biol; 1999 Mar; 19(3):2109-17. PubMed ID: 10022898
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts.
    Dulić V; Beney GE; Frebourg G; Drullinger LF; Stein GH
    Mol Cell Biol; 2000 Sep; 20(18):6741-54. PubMed ID: 10958672
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Complex mechanisms underlying impaired activation of Cdk4 and Cdk2 in replicative senescence: roles of p16, p21, and cyclin D1.
    Morisaki H; Ando A; Nagata Y; Pereira-Smith O; Smith JR; Ikeda K; Nakanishi M
    Exp Cell Res; 1999 Dec; 253(2):503-10. PubMed ID: 10585273
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function.
    Foster JS; Henley DC; Bukovsky A; Seth P; Wimalasena J
    Mol Cell Biol; 2001 Feb; 21(3):794-810. PubMed ID: 11154267
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p16INK4A mediates cyclin dependent kinase 4 and 6 inhibition in senescent prostatic epithelial cells.
    Sandhu C; Peehl DM; Slingerland J
    Cancer Res; 2000 May; 60(10):2616-22. PubMed ID: 10825132
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes.
    McConnell BB; Gregory FJ; Stott FJ; Hara E; Peters G
    Mol Cell Biol; 1999 Mar; 19(3):1981-9. PubMed ID: 10022885
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.
    Prall OW; Sarcevic B; Musgrove EA; Watts CK; Sutherland RL
    J Biol Chem; 1997 Apr; 272(16):10882-94. PubMed ID: 9099745
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts.
    Alcorta DA; Xiong Y; Phelps D; Hannon G; Beach D; Barrett JC
    Proc Natl Acad Sci U S A; 1996 Nov; 93(24):13742-7. PubMed ID: 8943005
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.
    Hsieh FF; Barnett LA; Green WF; Freedman K; Matushansky I; Skoultchi AI; Kelley LL
    Blood; 2000 Oct; 96(8):2746-54. PubMed ID: 11023508
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo.
    Ezhevsky SA; Ho A; Becker-Hapak M; Davis PK; Dowdy SF
    Mol Cell Biol; 2001 Jul; 21(14):4773-84. PubMed ID: 11416152
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a).
    Mitra J; Dai CY; Somasundaram K; El-Deiry WS; Satyamoorthy K; Herlyn M; Enders GH
    Mol Cell Biol; 1999 May; 19(5):3916-28. PubMed ID: 10207115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21(WAF1) expression.
    Wyllie F; Haughton M; Bartek J; Rowson J; Wynford-Thomas D
    Exp Cell Res; 2003 May; 285(2):236-42. PubMed ID: 12706118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.
    Sandhu C; Donovan J; Bhattacharya N; Stampfer M; Worland P; Slingerland J
    Oncogene; 2000 Nov; 19(47):5314-23. PubMed ID: 11103932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver.
    Albrecht JH; Poon RY; Ahonen CL; Rieland BM; Deng C; Crary GS
    Oncogene; 1998 Apr; 16(16):2141-50. PubMed ID: 9572495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of cyclin-dependent kinase inactivation by progestins.
    Musgrove EA; Swarbrick A; Lee CS; Cornish AL; Sutherland RL
    Mol Cell Biol; 1998 Apr; 18(4):1812-25. PubMed ID: 9528753
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence.
    Brookes S; Gagrica S; Sanij E; Rowe J; Gregory FJ; Hara E; Peters G
    Cell Cycle; 2015; 14(8):1164-73. PubMed ID: 25695870
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Melanin accumulation accelerates melanocyte senescence by a mechanism involving p16INK4a/CDK4/pRB and E2F1.
    Bandyopadhyay D; Medrano EE
    Ann N Y Acad Sci; 2000 Jun; 908():71-84. PubMed ID: 10911949
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.
    Reynisdóttir I; Polyak K; Iavarone A; Massagué J
    Genes Dev; 1995 Aug; 9(15):1831-45. PubMed ID: 7649471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence.
    Frippiat C; Remacle J; Toussaint O
    Int J Biochem Cell Biol; 2003 Feb; 35(2):246-54. PubMed ID: 12479875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 59.