BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

442 related articles for article (PubMed ID: 10026298)

  • 1. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.
    Pilch DS; Poklar N; Baird EE; Dervan PB; Breslauer KJ
    Biochemistry; 1999 Feb; 38(7):2143-51. PubMed ID: 10026298
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the A.T/T.A degeneracy of pyrrole--imidazole polyamide recognition in the minor groove of DNA.
    White S; Baird EE; Dervan PB
    Biochemistry; 1996 Sep; 35(38):12532-7. PubMed ID: 8823190
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discrimination of hairpin polyamides with an alpha-substituted-gamma-aminobutyric acid as a 5'-TG-3' reader in DNA minor groove.
    Zhang W; Bando T; Sugiyama H
    J Am Chem Soc; 2006 Jul; 128(27):8766-76. PubMed ID: 16819870
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination.
    Pilch DS; Poklar N; Gelfand CA; Law SM; Breslauer KJ; Baird EE; Dervan PB
    Proc Natl Acad Sci U S A; 1996 Aug; 93(16):8306-11. PubMed ID: 8710866
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combinatorial determination of sequence specificity for nanomolar DNA-binding hairpin polyamides.
    Vashisht Gopal YN; Van Dyke MW
    Biochemistry; 2003 Jun; 42(22):6891-903. PubMed ID: 12779344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular recognition of DNA base pairs by the formamido/pyrrole and formamido/imidazole pairings in stacked polyamides.
    Buchmueller KL; Staples AM; Uthe PB; Howard CM; Pacheco KA; Cox KK; Henry JA; Bailey SL; Horick SM; Nguyen B; Wilson WD; Lee M
    Nucleic Acids Res; 2005; 33(3):912-21. PubMed ID: 15703305
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
    Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'.
    Han YW; Kashiwazaki G; Morinaga H; Matsumoto T; Hashiya K; Bando T; Harada Y; Sugiyama H
    Bioorg Med Chem; 2013 Sep; 21(17):5436-41. PubMed ID: 23810670
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sequence specific fluorescence detection of double strand DNA.
    Rucker VC; Foister S; Melander C; Dervan PB
    J Am Chem Soc; 2003 Feb; 125(5):1195-202. PubMed ID: 12553822
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA minor-groove recognition by 3-methylthiophene/pyrrole pair.
    Doss RM; Marques MA; Foister S; Dervan PB
    Chem Biodivers; 2004 Jun; 1(6):886-99. PubMed ID: 17191889
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
    Westrate L; Mackay H; Brown T; Nguyen B; Kluza J; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2009 Jun; 48(24):5679-88. PubMed ID: 19419200
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Base pair recognition of the stereochemically alpha-substituted gamma-turn of pyrrole/imidazole hairpin polyamides.
    Zhang W; Minoshima M; Sugiyama H
    J Am Chem Soc; 2006 Nov; 128(46):14905-12. PubMed ID: 17105301
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
    Buchmueller KL; Staples AM; Howard CM; Horick SM; Uthe PB; Le NM; Cox KK; Nguyen B; Pacheco KA; Wilson WD; Lee M
    J Am Chem Soc; 2005 Jan; 127(2):742-50. PubMed ID: 15643900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Physical and structural basis for the strong interactions of the -ImPy- central pairing motif in the polyamide f-ImPyIm.
    Buchmueller KL; Bailey SL; Matthews DA; Taherbhai ZT; Register JK; Davis ZS; Bruce CD; O'Hare C; Hartley JA; Lee M
    Biochemistry; 2006 Nov; 45(45):13551-65. PubMed ID: 17087509
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands.
    White S; Szewczyk JW; Turner JM; Baird EE; Dervan PB
    Nature; 1998 Jan; 391(6666):468-71. PubMed ID: 9461213
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetics of pyrrole-imidazole polyamides after intravenous administration in rat.
    Fukasawa A; Aoyama T; Nagashima T; Fukuda N; Ueno T; Sugiyama H; Nagase H; Matsumoto Y
    Biopharm Drug Dispos; 2009 Mar; 30(2):81-9. PubMed ID: 19226654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand.
    McBryant SJ; Baird EE; Trauger JW; Dervan PB; Gottesfeld JM
    J Mol Biol; 1999 Mar; 286(4):973-81. PubMed ID: 10047474
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
    Kielkopf CL; Bremer RE; White S; Szewczyk JW; Turner JM; Baird EE; Dervan PB; Rees DC
    J Mol Biol; 2000 Jan; 295(3):557-67. PubMed ID: 10623546
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of a hairpin polyamide on DNA melting: comparison with distamycin and Hoechst 33258.
    James PL; Le Strat L; Ellervik U; Bratwall C; Nordén B; Brown T; Fox KR
    Biophys Chem; 2004 Nov; 111(3):205-12. PubMed ID: 15501563
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular design of a pyrrole-imidazole hairpin polyamides for effective DNA alkylation.
    Bando T; Narita A; Saito I; Sugiyama H
    Chemistry; 2002 Oct; 8(20):4781-90. PubMed ID: 12561118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.