These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 10029522)

  • 1. Kinetic mechanism of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase.
    Digits JA; Hedstrom L
    Biochemistry; 1999 Feb; 38(8):2295-306. PubMed ID: 10029522
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products.
    Wang W; Hedstrom L
    Biochemistry; 1997 Jul; 36(28):8479-83. PubMed ID: 9214292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acid-base catalysis in the chemical mechanism of inosine monophosphate dehydrogenase.
    Markham GD; Bock CL; Schalk-Hihi C
    Biochemistry; 1999 Apr; 38(14):4433-40. PubMed ID: 10194364
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid.
    Digits JA; Hedstrom L
    Biochemistry; 1999 Nov; 38(46):15388-97. PubMed ID: 10563825
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Is Arg418 the catalytic base required for the hydrolysis step of the IMP dehydrogenase reaction?
    Guillén Schlippe YV; Hedstrom L
    Biochemistry; 2005 Sep; 44(35):11700-7. PubMed ID: 16128570
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction.
    Guillén Schlippe YV; Riera TV; Seyedsayamdost MR; Hedstrom L
    Biochemistry; 2004 Apr; 43(15):4511-21. PubMed ID: 15078097
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IMP dehydrogenase: mechanism of action and inhibition.
    Hedstrom L
    Curr Med Chem; 1999 Jul; 6(7):545-60. PubMed ID: 10390600
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of inosine 5'-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide 5'-monophosphate.
    Wang W; Papov VV; Minakawa N; Matsuda A; Biemann K; Hedstrom L
    Biochemistry; 1996 Jan; 35(1):95-101. PubMed ID: 8555204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex.
    Whitby FG; Luecke H; Kuhn P; Somoza JR; Huete-Perez JA; Phillips JD; Hill CP; Fletterick RJ; Wang CC
    Biochemistry; 1997 Sep; 36(35):10666-74. PubMed ID: 9271497
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the mechanism of inosine monophosphate dehydrogenase with kinetic isotope effects and NMR determination of the hydride transfer stereospecificity.
    Xiang B; Markham GD
    Arch Biochem Biophys; 1997 Dec; 348(2):378-82. PubMed ID: 9434751
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The conformation of NADH bound to inosine 5'-monophosphate dehydrogenase determined by transferred nuclear Overhauser effect spectroscopy.
    Schalk-Hihi C; Zhang YZ; Markham GD
    Biochemistry; 1998 May; 37(20):7608-16. PubMed ID: 9585576
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
    Hedstrom L; Wang CC
    Biochemistry; 1990 Jan; 29(4):849-54. PubMed ID: 1971185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Guanidine derivatives rescue the Arg418Ala mutation of Tritrichomonas foetus IMP dehydrogenase.
    Guillén Schlippe YV; Hedstrom L
    Biochemistry; 2005 Dec; 44(50):16695-700. PubMed ID: 16342959
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tritrichomonas foetus: a strategy for structure-based inhibitor design of a protozoan inosine-5'-monophosphate dehydrogenase.
    Luecke H; Prosise GL; Whitby FG
    Exp Parasitol; 1997 Nov; 87(3):203-11. PubMed ID: 9371085
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.
    Fleming MA; Chambers SP; Connelly PR; Nimmesgern E; Fox T; Bruzzese FJ; Hoe ST; Fulghum JR; Livingston DJ; Stuver CM; Sintchak MD; Wilson KP; Thomson JA
    Biochemistry; 1996 Jun; 35(22):6990-7. PubMed ID: 8679523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of Tritrichomonas foetus inosine monophosphate dehydrogenase in complex with the inhibitor ribavirin monophosphate reveals a catalysis-dependent ion-binding site.
    Prosise GL; Wu JZ; Luecke H
    J Biol Chem; 2002 Dec; 277(52):50654-9. PubMed ID: 12235158
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.
    Gan L; Petsko GA; Hedstrom L
    Biochemistry; 2002 Nov; 41(44):13309-17. PubMed ID: 12403633
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
    Prosise GL; Luecke H
    J Mol Biol; 2003 Feb; 326(2):517-27. PubMed ID: 12559919
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Monovalent cation activation in Escherichia coli inosine 5'-monophosphate dehydrogenase.
    Kerr KM; Cahoon M; Bosco DA; Hedstrom L
    Arch Biochem Biophys; 2000 Mar; 375(1):131-7. PubMed ID: 10683258
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
    Munagala NR; Wang CC
    Biochemistry; 1998 Nov; 37(47):16612-9. PubMed ID: 9843428
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.