BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

412 related articles for article (PubMed ID: 10048151)

  • 1. The effect of cotinine or cigarette smoke co-administration on the formation of O6-methylguanine adducts in the lung and liver of A/J mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Brown BG; Chang CJ; Ayres PH; Lee CK; Doolittle DJ
    Toxicol Sci; 1999 Jan; 47(1):33-9. PubMed ID: 10048151
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
    Brown BG; Richter E; Tricker AR; Ayres PH; Doolittle DJ
    Chem Biol Interact; 2001 Nov; 138(2):125-35. PubMed ID: 11672696
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B; Cox JE; Upadhyaya P; Amin S; Desai D; Hoffmann D; el-Bayoumy K
    Carcinogenesis; 1996 Apr; 17(4):749-53. PubMed ID: 8625486
    [TBL] [Abstract][Full Text] [Related]  

  • 4. O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
    Peterson LA; Hecht SS
    Cancer Res; 1991 Oct; 51(20):5557-64. PubMed ID: 1913675
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM; Kenney PM; Peterson LA
    Chem Res Toxicol; 2003 Jan; 16(1):1-6. PubMed ID: 12693024
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Immunocytochemical identification of DNA adducts, O6-methylguanine and 7-methylguanine, in respiratory and other tissues of rat, mouse and Syrian hamster exposed to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Van Benthem J; Feron VJ; Leeman WR; Wilmer JW; Vermeulen E; den Engelse L; Scherer E
    Carcinogenesis; 1994 Sep; 15(9):2023-9. PubMed ID: 7522985
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.
    Morse MA; LaGreca SD; Amin SG; Chung FL
    Cancer Res; 1990 May; 50(9):2613-7. PubMed ID: 2328487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effect of tobacco smoke, nicotine, and cotinine on the mutagenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).
    Brown B; Avalos J; Lee C; Doolittle D
    Mutat Res; 2001 Jul; 494(1-2):21-9. PubMed ID: 11423342
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Belinsky SA; Foley JF; White CM; Anderson MW; Maronpot RR
    Cancer Res; 1990 Jun; 50(12):3772-80. PubMed ID: 2340522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR; McIntee EJ; Kenney PM; Upadhyaya P; Peterson LA; Hecht SS
    Chem Res Toxicol; 2003 Jun; 16(6):794-806. PubMed ID: 12807363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An analysis of the role of tobacco-specific nitrosamines in the carcinogenicity of tobacco smoke.
    Brown BG; Borschke AJ; Doolittle DJ
    Nonlinearity Biol Toxicol Med; 2003 Apr; 1(2):179-98. PubMed ID: 19330121
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
    Morse MA; Amin SG; Hecht SS; Chung FL
    Cancer Res; 1989 Jun; 49(11):2894-7. PubMed ID: 2720649
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Accumulation and persistence of DNA adducts in respiratory tissue of rats following multiple administrations of the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
    Belinsky SA; White CM; Boucheron JA; Richardson FC; Swenberg JA; Anderson M
    Cancer Res; 1986 Mar; 46(3):1280-4. PubMed ID: 3943097
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of nicotine, cotinine and phenethyl isothiocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in the Syrian golden hamster.
    Richter E; Tricker AR
    Toxicology; 2002 Sep; 179(1-2):95-103. PubMed ID: 12204546
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of nicotine or cotinine on metabolism of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Schulze J; Schrader E; Foth H; Kahl GF; Richter E
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar; 357(3):344-50. PubMed ID: 9550308
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative levels of O6-methylguanine, pyridyloxobutyl-, and pyridylhydroxybutyl-DNA adducts in lung and liver of rats treated chronically with the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Upadhyaya P; Lindgren BR; Hecht SS
    Drug Metab Dispos; 2009 Jun; 37(6):1147-51. PubMed ID: 19324941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Zhang S; Wang M; Villalta PW; Lindgren BR; Upadhyaya P; Lao Y; Hecht SS
    Chem Res Toxicol; 2009 May; 22(5):926-36. PubMed ID: 19358518
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tumorigenic activity of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanol (iso-NNAL) and N'-nitrosonornicotine (NNN) on topical application to Sencar mice.
    LaVoie EJ; Prokopczyk G; Rigotty J; Czech A; Rivenson A; Adams JD
    Cancer Lett; 1987 Nov; 37(3):277-83. PubMed ID: 3677059
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of DNA methylation in the activation of proto-oncogenes and the induction of pulmonary neoplasia by nitrosamines.
    Belinsky SA; Devereux TR; Anderson MW
    Mutat Res; 1990; 233(1-2):105-16. PubMed ID: 2233792
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Staretz ME; Foiles PG; Miglietta LM; Hecht SS
    Cancer Res; 1997 Jan; 57(2):259-66. PubMed ID: 9000565
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.