These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 10052974)

  • 1. New water-soluble duocarmycin derivatives: synthesis and antitumor activity of A-ring pyrrole compounds bearing beta-heteroarylacryloyl groups.
    Amishiro N; Nagamura S; Kobayashi E; Gomi K; Saito H
    J Med Chem; 1999 Feb; 42(4):669-76. PubMed ID: 10052974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds.
    Amishiro N; Okamoto A; Murakata C; Tamaoki T; Okabe M; Saito H
    J Med Chem; 1999 Jul; 42(15):2946-60. PubMed ID: 10425104
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing cinnamoyl groups.
    Nagamura S; Asai A; Amishiro N; Kobayashi E; Gomi K; Saito H
    J Med Chem; 1997 Mar; 40(6):972-9. PubMed ID: 9083487
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antitumor activity of duocarmycin derivatives: a-ring pyrrole compounds bearing 5-membered heteroarylacryloyl groups.
    Amishiro N; Nagamura S; Kobayashi E; Okamoto A; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1999 Oct; 47(10):1393-403. PubMed ID: 10553637
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and antitumor activity of duocarmycin derivatives: modification at C-8 position of A-ring pyrrole compounds bearing the simplified DNA-binding groups.
    Amishiro N; Nagamura S; Murakata C; Okamoto A; Kobayashi E; Asada M; Gomi K; Tamaoki T; Okabe M; Yamaguchi N; Yamaguchi K; Saito H
    Bioorg Med Chem; 2000 Feb; 8(2):381-91. PubMed ID: 10722161
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing beta-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group.
    Amishiro N; Nagamura S; Kobayashi E; Okamoto A; Gomi K; Okabe M; Saito H
    Bioorg Med Chem; 2000 Jul; 8(7):1637-43. PubMed ID: 10976511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characteristics of antitumor activity of KW-2189, a novel water-soluble derivative of duocarmycin, against murine and human tumors.
    Kobayashi E; Okamoto A; Asada M; Okabe M; Nagamura S; Asai A; Saito H; Gomi K; Hirata T
    Cancer Res; 1994 May; 54(9):2404-10. PubMed ID: 8162588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antitumor activity of duocarmycin derivatives: modification of segment A of duocarmycin B2.
    Nagamura S; Asai A; Kanda Y; Kobayashi E; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1996 Sep; 44(9):1723-30. PubMed ID: 8855367
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole analogues of duocarmycin B2.
    Nagamura S; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem; 1996 Aug; 4(8):1379-91. PubMed ID: 8879561
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antitumor activity of duocarmycin derivatives: modification at the C-7 position of segment-A of A-ring pyrrole compounds.
    Amishiro N; Okamoto A; Okabe M; Saito H
    Bioorg Med Chem; 2000 May; 8(5):1195-201. PubMed ID: 10882029
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
    Berry JM; Bradshaw TD; Fichtner I; Ren R; Schwalbe CH; Wells G; Chew EH; Stevens MF; Westwell AD
    J Med Chem; 2005 Jan; 48(2):639-44. PubMed ID: 15658878
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity.
    Mai A; Massa S; Cerbara I; Valente S; Ragno R; Bottoni P; Scatena R; Loidl P; Brosch G
    J Med Chem; 2004 Feb; 47(5):1098-109. PubMed ID: 14971890
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners.
    Beria I; Baraldi PG; Cozzi P; Caldarelli M; Geroni C; Marchini S; Mongelli N; Romagnoli R
    J Med Chem; 2004 May; 47(10):2611-23. PubMed ID: 15115402
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and in vitro and in vivo antitumor activity of 2-phenylpyrroloquinolin-4-ones.
    Ferlin MG; Chiarelotto G; Gasparotto V; Dalla Via L; Pezzi V; Barzon L; Palù G; Castagliuolo I
    J Med Chem; 2005 May; 48(9):3417-27. PubMed ID: 15857148
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 5-Amino-1-(chloromethyl)-1,2-dihydro-3H-benz[e]indoles: relationships between structure and cytotoxicity for analogues bearing different DNA minor groove binding subunits.
    Atwell GJ; Milbank JJ; Wilson WR; Hogg A; Denny WA
    J Med Chem; 1999 Aug; 42(17):3400-11. PubMed ID: 10464026
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK; Guan J; Tachibana Y; Bastow KF; Cho SJ; Cheng HH; Cheng YC; Gurwith M; Lee KH
    J Med Chem; 1999 Jul; 42(13):2441-6. PubMed ID: 10395485
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions.
    Kemnitzer W; Drewe J; Jiang S; Zhang H; Crogan-Grundy C; Labreque D; Bubenick M; Attardo G; Denis R; Lamothe S; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
    J Med Chem; 2008 Feb; 51(3):417-23. PubMed ID: 18197614
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity.
    Su TL; Lin YW; Chou TC; Zhang X; Bacherikov VA; Chen CH; Liu LF; Tsai TJ
    J Med Chem; 2006 Jun; 49(12):3710-8. PubMed ID: 16759114
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new class of potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: structure-activity relationships for a series of 9-alkoxymethyl-12-(3-hydroxypropyl)indeno[2,1-a]pyrrolo[3,4-c]carbazole-5-ones and the identification of CEP-5214 and its dimethylglycine ester prodrug clinical candidate CEP-7055.
    Gingrich DE; Reddy DR; Iqbal MA; Singh J; Aimone LD; Angeles TS; Albom M; Yang S; Ator MA; Meyer SL; Robinson C; Ruggeri BA; Dionne CA; Vaught JL; Mallamo JP; Hudkins RL
    J Med Chem; 2003 Dec; 46(25):5375-88. PubMed ID: 14640546
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on duocarmycin SA and its derivatives.
    Nagamura S; Asai A; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem; 1997 Mar; 5(3):623-30. PubMed ID: 9113339
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.