These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 10068285)

  • 21. Increasing throughput and information content for in vitro drug metabolism experiments using ultra-performance liquid chromatography coupled to a quadrupole time-of-flight mass spectrometer.
    Castro-Perez J; Plumb R; Granger JH; Beattie I; Joncour K; Wright A
    Rapid Commun Mass Spectrom; 2005; 19(6):843-8. PubMed ID: 15723446
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Application of stable isotope labeled glutathione and rapid scanning mass spectrometers in detecting and characterizing reactive metabolites.
    Mutlib A; Lam W; Atherton J; Chen H; Galatsis P; Stolle W
    Rapid Commun Mass Spectrom; 2005; 19(23):3482-92. PubMed ID: 16261644
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development of a two-dimensional liquid chromatography system for isolation of drug metabolites.
    Jayamanne M; Granelli I; Tjernberg A; Edlund PO
    J Pharm Biomed Anal; 2010 Feb; 51(3):649-57. PubMed ID: 19815360
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.
    Chovan LE; Black-Schaefer C; Dandliker PJ; Lau YY
    Rapid Commun Mass Spectrom; 2004; 18(24):3105-12. PubMed ID: 15565734
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Metabolite identification via LC-SPE-NMR-MS of the in vitro biooxidation products of a lead mGlu5 allosteric antagonist and impact on the improvement of metabolic stability in the series.
    Ceccarelli SM; Schlotterbeck G; Boissin P; Binder M; Buettelmann B; Hanlon S; Jaeschke G; Kolczewski S; Kupfer E; Peters JU; Porter RH; Prinssen EP; Rueher M; Ruf I; Spooren W; Stämpfli A; Vieira E
    ChemMedChem; 2008 Jan; 3(1):136-44. PubMed ID: 17994660
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of drug metabolites in biological matrices by intelligent automated liquid chromatography/tandem mass spectrometry.
    Lopez LL; Yu X; Cui D; Davis MR
    Rapid Commun Mass Spectrom; 1998; 12(22):1756-60. PubMed ID: 9853385
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Integrating qualitative and quantitative liquid chromatography/tandem mass spectrometric analysis to support drug discovery.
    Poon GK; Kwei G; Wang R; Lyons K; Chen Q; Didolkar V; Hop CE
    Rapid Commun Mass Spectrom; 1999; 13(19):1943-50. PubMed ID: 10487941
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Applicability of bioanalysis of multiple analytes in drug discovery and development: review of select case studies including assay development considerations.
    Srinivas NR
    Biomed Chromatogr; 2006 May; 20(5):383-414. PubMed ID: 16307470
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Development of an automated mass spectrometry system for the quantitative analysis of liver microsomal incubation samples: a tool for rapid screening of new compounds for metabolic stability.
    Korfmacher WA; Palmer CA; Nardo C; Dunn-Meynell K; Grotz D; Cox K; Lin CC; Elicone C; Liu C; Duchoslav E
    Rapid Commun Mass Spectrom; 1999; 13(10):901-7. PubMed ID: 10353225
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry.
    Ma S; Subramanian R
    J Mass Spectrom; 2006 Sep; 41(9):1121-39. PubMed ID: 16967439
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites.
    Dalvie D; Obach RS; Kang P; Prakash C; Loi CM; Hurst S; Nedderman A; Goulet L; Smith E; Bu HZ; Smith DA
    Chem Res Toxicol; 2009 Feb; 22(2):357-68. PubMed ID: 19146377
    [TBL] [Abstract][Full Text] [Related]  

  • 32. In vitro metabolic fate of a novel structural class: evidence for the formation of a reactive intermediate on a benzothiophene moiety.
    Evans CA; Fries HE; Ward KW
    Chem Biol Interact; 2005 Feb; 152(1):25-36. PubMed ID: 15766920
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Recent advances in applications of liquid chromatography-tandem mass spectrometry to the analysis of reactive drug metabolites.
    Ma S; Zhu M
    Chem Biol Interact; 2009 Apr; 179(1):25-37. PubMed ID: 18848531
    [TBL] [Abstract][Full Text] [Related]  

  • 34. High-throughput, accurate mass liquid chromatography/tandem mass spectrometry on a quadrupole time-of-flight system as a 'first-line' approach for metabolite identification studies.
    Tiller PR; Yu S; Castro-Perez J; Fillgrove KL; Baillie TA
    Rapid Commun Mass Spectrom; 2008 Apr; 22(7):1053-61. PubMed ID: 18327855
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Supercritical fluid chromatography/tandem mass spectrometric method for analysis of pharmaceutical compounds in metabolic stability samples.
    Hsieh Y; Favreau L; Schwerdt J; Cheng KC
    J Pharm Biomed Anal; 2006 Feb; 40(3):799-804. PubMed ID: 16095863
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Metabolite identification in drug discovery.
    Watt AP; Mortishire-Smith RJ; Gerhard U; Thomas SR
    Curr Opin Drug Discov Devel; 2003 Jan; 6(1):57-65. PubMed ID: 12613277
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Complete profiling and characterization of in vitro nefazodone metabolites using two different tandem mass spectrometric platforms.
    Li AC; Shou WZ; Mai TT; Jiang XY
    Rapid Commun Mass Spectrom; 2007; 21(24):4001-8. PubMed ID: 18000840
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Generic fast gradient liquid chromatography/tandem mass spectrometry techniques for the assessment of the in vitro permeability across the blood-brain barrier in drug discovery.
    Chu I; Liu F; Soares A; Kumari P; Nomeir AA
    Rapid Commun Mass Spectrom; 2002; 16(15):1501-5. PubMed ID: 12125028
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.
    Rousu T; Pelkonen O; Tolonen A
    Rapid Commun Mass Spectrom; 2009 Mar; 23(6):843-55. PubMed ID: 19224530
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Simultaneously quantifying parent drugs and screening for metabolites in plasma pharmacokinetic samples using selected reaction monitoring information-dependent acquisition on a QTrap instrument.
    Li AC; Alton D; Bryant MS; Shou WZ
    Rapid Commun Mass Spectrom; 2005; 19(14):1943-50. PubMed ID: 15954168
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.