234 related articles for article (PubMed ID: 10069380)
1. Impact of 9-(2-phosphonylmethoxyethyl)adenine on (deoxy)ribonucleotide metabolism and nucleic acid synthesis in tumor cells.
Hatse S; De Clercq E; Balzarini J
FEBS Lett; 1999 Feb; 445(1):92-7. PubMed ID: 10069380
[TBL] [Abstract][Full Text] [Related]
2. 9-(2-Phosphonylmethoxyethyl)adenine induces tumor cell differentiation or cell death by blocking cell cycle progression through the S phase.
Hatse S; Schols D; De Clercq E; Balzarini J
Cell Growth Differ; 1999 Jun; 10(6):435-46. PubMed ID: 10392905
[TBL] [Abstract][Full Text] [Related]
3. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
Yin MB; Guo B; Panadero A; Frank C; Wrzosek C; Slocum HK; Rustum YM
Exp Cell Res; 1999 Feb; 247(1):189-99. PubMed ID: 10047461
[TBL] [Abstract][Full Text] [Related]
4. Enhanced 9-(2-phosphonylmethoxyethyl)adenine secretion by a specific, indomethacin-sensitive efflux pump in a mutant 9-(2-phosphonylmethoxyethyl)adenine-resistant human erythroleukemia K562 cell line.
Hatse S; De Clercq E; Balzarini J
Mol Pharmacol; 1998 Nov; 54(5):907-17. PubMed ID: 9804626
[TBL] [Abstract][Full Text] [Related]
5. N6-cyclopropyl-PMEDAP: a novel derivative of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) with distinct metabolic, antiproliferative, and differentiation-inducing properties.
Hatse S; Naesens L; De Clercq E; Balzarini J
Biochem Pharmacol; 1999 Jul; 58(2):311-23. PubMed ID: 10423173
[TBL] [Abstract][Full Text] [Related]
6. 9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis.
Kramata P; Downey KM
Mol Pharmacol; 1999 Dec; 56(6):1262-70. PubMed ID: 10570054
[TBL] [Abstract][Full Text] [Related]
7. Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts.
Nicander B; Reichard P
J Biol Chem; 1985 May; 260(9):5376-81. PubMed ID: 3921544
[TBL] [Abstract][Full Text] [Related]
8. Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl) adenine (PMEA).
Balzarini J; Hatse S; Naesens L; De Clercq E
Biochim Biophys Acta; 1998 Mar; 1402(1):29-38. PubMed ID: 9551083
[TBL] [Abstract][Full Text] [Related]
9. The effect of ara-C-induced inhibition of DNA synthesis on its cellular pharmacology.
Wang LM; White JC; Capizzi RL
Cancer Chemother Pharmacol; 1990; 25(6):418-24. PubMed ID: 2311169
[TBL] [Abstract][Full Text] [Related]
10. Evidence for distinction of the differentiation-inducing activities and cytostatic properties of 9-(2-phosphonylmethoxyethyl)adenine and a variety of differentiation-inducing agents in human erythroleukemia K562 cells.
Hatse S; De Clercq E; Balzarini J
Mol Pharmacol; 1996 Nov; 50(5):1231-42. PubMed ID: 8913355
[TBL] [Abstract][Full Text] [Related]
11. Evaluation of ribonucleoside and deoxyribonucleoside triphosphate pools in cultured leukemia cells during exposure to methotrexate or methotrexate plus thymidine.
Kinahan JJ; Otten M; Grindey GB
Cancer Res; 1979 Sep; 39(9):3531-9. PubMed ID: 476679
[TBL] [Abstract][Full Text] [Related]
12. Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells.
Moyer JD; Smith PA; Levy EJ; Handschumacher RE
Cancer Res; 1982 Nov; 42(11):4525-31. PubMed ID: 7127293
[TBL] [Abstract][Full Text] [Related]
13. Involvement of a substrate cycle between thymidine and thymidylate in the regulation of DNA precursor pool in ehrlich ascites tumour.
He Q; Skog S
Cell Physiol Biochem; 2002; 12(5-6):305-14. PubMed ID: 12438766
[TBL] [Abstract][Full Text] [Related]
14. [Studies on the thymidine-triphosphate synthesis in malignant tumors. I. Effects of thymidine on deoxyribonucleoside triphosphate pools and deoxyribonucleic acid synthesis (author's transl)].
Kummer D; Kraml F
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol; 1977 Jan; 88(2):129-43. PubMed ID: 139036
[TBL] [Abstract][Full Text] [Related]
15. Thymidylate synthesis in a folate deprived cell line.
Marquet J; Zittoun J; Weynants C; Zittoun R
Br J Haematol; 1981 Sep; 49(1):87-95. PubMed ID: 7272232
[TBL] [Abstract][Full Text] [Related]
16. Characterization of a thymidylate synthase (TS)-inducible cell line: a model system for studying sensitivity to TS- and non-TS-targeted chemotherapies.
Longley DB; Ferguson PR; Boyer J; Latif T; Lynch M; Maxwell P; Harkin DP; Johnston PG
Clin Cancer Res; 2001 Nov; 7(11):3533-9. PubMed ID: 11705873
[TBL] [Abstract][Full Text] [Related]
17. Resveratrol induces prostate cancer cell entry into s phase and inhibits DNA synthesis.
Kuwajerwala N; Cifuentes E; Gautam S; Menon M; Barrack ER; Reddy GP
Cancer Res; 2002 May; 62(9):2488-92. PubMed ID: 11980638
[TBL] [Abstract][Full Text] [Related]
18. The human immunodeficiency virus(HIV) inhibitor 9-(2-phosphonylmethoxyethyl)adenine (PMEA) is a strong inducer of differentiation of several tumor cell lines.
Balzarini J; Verstuyf A; Hatse S; Goebels J; Sobis H; Vandeputte M; De Clercq E
Int J Cancer; 1995 Mar; 61(1):130-7. PubMed ID: 7705926
[TBL] [Abstract][Full Text] [Related]
19. Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.
Parker WB; Shaddix SC; Chang CH; White EL; Rose LM; Brockman RW; Shortnacy AT; Montgomery JA; Secrist JA; Bennett LL
Cancer Res; 1991 May; 51(9):2386-94. PubMed ID: 1707752
[TBL] [Abstract][Full Text] [Related]
20. Purine modulation of thymidine activity in L1210 leukemia cells in vitro.
Leyva A; Appel H; Pinedo HM
Leuk Res; 1982; 6(4):483-90. PubMed ID: 7144228
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
