75 related articles for article (PubMed ID: 10072682)
1. Bisquaternary ligands of the common allosteric site of M2 acetylcholine receptors: search for the minimum essential distances between the pharmacophoric elements.
Nassif-Makki T; Tränkle C; Zlotos D; Bejeuhr G; Cambareri A; Pfletschinger C; Kostenis E; Mohr K; Holzgrabe U
J Med Chem; 1999 Mar; 42(5):849-58. PubMed ID: 10072682
[TBL] [Abstract][Full Text] [Related]
2. Muscarinic allosteric enhancers of ligand binding: pivotal pharmacophoric elements in hexamethonio-type agents.
Muth M; Sennwitz M; Mohr K; Holzgrabe U
J Med Chem; 2005 Mar; 48(6):2212-7. PubMed ID: 15771463
[TBL] [Abstract][Full Text] [Related]
3. Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors.
Tränkle C; Weyand O; Voigtländer U; Mynett A; Lazareno S; Birdsall NJ; Mohr K
Mol Pharmacol; 2003 Jul; 64(1):180-90. PubMed ID: 12815174
[TBL] [Abstract][Full Text] [Related]
4. Identification of a [3H]Ligand for the common allosteric site of muscarinic acetylcholine M2 receptors.
Tränkle C; Mies-Klomfass E; Cid MH; Holzgrabe U; Mohr K
Mol Pharmacol; 1998 Jul; 54(1):139-45. PubMed ID: 9658199
[TBL] [Abstract][Full Text] [Related]
5. Development of a new type of allosteric modulator of muscarinic receptors: hybrids of the antagonist AF-DX 384 and the hexamethonio derivative W84.
Mohr M; Heller E; Ataie A; Mohr K; Holzgrabe U
J Med Chem; 2004 Jun; 47(12):3324-7. PubMed ID: 15163212
[TBL] [Abstract][Full Text] [Related]
6. Probing the pharmacophore for allosteric ligands of muscarinic M2 receptors: SAR and QSAR studies in a series of bisquaternary salts of caracurine V and related ring systems.
Zlotos DP; Buller S; Stiefl N; Baumann K; Mohr K
J Med Chem; 2004 Jul; 47(14):3561-71. PubMed ID: 15214783
[TBL] [Abstract][Full Text] [Related]
7. Search for lead structures to develop new allosteric modulators of muscarinic receptors.
Tränkle C; Kostenis E; Burgmer U; Mohr K
J Pharmacol Exp Ther; 1996 Nov; 279(2):926-33. PubMed ID: 8930201
[TBL] [Abstract][Full Text] [Related]
8. Systematic development of high affinity bis(ammonio)alkane-type allosteric enhancers of muscarinic ligand binding.
Muth M; Bender W; Scharfenstein O; Holzgrabe U; Balatkova E; Tränkle C; Mohr K
J Med Chem; 2003 Mar; 46(6):1031-40. PubMed ID: 12620079
[TBL] [Abstract][Full Text] [Related]
9. Competition between positive and negative allosteric effectors on muscarinic receptors.
Proska J; Tucek S
Mol Pharmacol; 1995 Oct; 48(4):696-702. PubMed ID: 7476896
[TBL] [Abstract][Full Text] [Related]
10. First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor.
Elsinghorst PW; Cieslik JS; Mohr K; Tränkle C; Gütschow M
J Med Chem; 2007 Nov; 50(23):5685-95. PubMed ID: 17944454
[TBL] [Abstract][Full Text] [Related]
11. Divergent modes of action among cationic allosteric modulators of muscarinic M2 receptors.
Tränkle C; Mohr K
Mol Pharmacol; 1997 Apr; 51(4):674-82. PubMed ID: 9106634
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationships in a series of bisquaternary bisphthalimidine derivatives modulating the muscarinic M(2)-receptor allosterically.
Botero Cid HM; Tränkle C; Baumann K; Pick R; Mies-Klomfass E; Kostenis E; Mohr K; Holzgrabe U
J Med Chem; 2000 Jun; 43(11):2155-64. PubMed ID: 10841794
[TBL] [Abstract][Full Text] [Related]
13. A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor.
Steinfeld T; Mammen M; Smith JA; Wilson RD; Jasper JR
Mol Pharmacol; 2007 Aug; 72(2):291-302. PubMed ID: 17478612
[TBL] [Abstract][Full Text] [Related]
14. Interaction of Mg2+ with the allosteric site of muscarinic M2 receptors.
Burgmer U; Schulz U; Tränkle C; Mohr K
Naunyn Schmiedebergs Arch Pharmacol; 1998 Apr; 357(4):363-70. PubMed ID: 9606020
[TBL] [Abstract][Full Text] [Related]
15. 6H,13H-Pyrazino[1,2-a;4,5-a']diindole analogs: probing the pharmacophore for allosteric ligands of muscarinic M2 receptors.
Zlotos DP; Tränkle C; Abdelrahman A; Gündisch D; Radacki K; Braunschweig H; Mohr K
Bioorg Med Chem Lett; 2006 Mar; 16(6):1481-5. PubMed ID: 16387499
[TBL] [Abstract][Full Text] [Related]
16. Evidence for a multiple binding mode of bispyridinium-type allosteric modulators of muscarinic receptors.
Kostenis E; Botero Cid HM; Holzgrabe Y; Mohr K
Eur J Pharmacol; 1996 Oct; 314(3):385-92. PubMed ID: 8957263
[TBL] [Abstract][Full Text] [Related]
17. Muscarinic allosteric modulators: atypical structure-activity-relationships in bispyridinium-type compounds.
Sürig U; Gaal K; Kostenis E; Tränkle C; Mohr K; Holzgrabe U
Arch Pharm (Weinheim); 2006 Apr; 339(4):207-12. PubMed ID: 16572483
[TBL] [Abstract][Full Text] [Related]
18. Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.
May LT; Avlani VA; Langmead CJ; Herdon HJ; Wood MD; Sexton PM; Christopoulos A
Mol Pharmacol; 2007 Aug; 72(2):463-76. PubMed ID: 17525129
[TBL] [Abstract][Full Text] [Related]
19. Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors.
Krejcí A; Tucek S
Mol Pharmacol; 2001 Oct; 60(4):761-7. PubMed ID: 11562438
[TBL] [Abstract][Full Text] [Related]
20. Mutational disruption of a conserved disulfide bond in muscarinic acetylcholine receptors attenuates positive homotropic cooperativity between multiple allosteric sites and has subtype-dependent effects on the affinities of muscarinic allosteric ligands.
Huang XP; Ellis J
Mol Pharmacol; 2007 Mar; 71(3):759-68. PubMed ID: 17132687
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]