143 related articles for article (PubMed ID: 10072691)
1. Hypoxia-selective nitrobenzyloxycarbonyl derivatives of 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazines.
Shyam K; Penketh PG; Shapiro M; Belcourt MF; Loomis RH; Rockwell S; Sartorelli AC
J Med Chem; 1999 Mar; 42(5):941-6. PubMed ID: 10072691
[TBL] [Abstract][Full Text] [Related]
2. Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
Palmer BD; Wilson WR; Anderson RF; Boyd M; Denny WA
J Med Chem; 1996 Jun; 39(13):2518-28. PubMed ID: 8691449
[TBL] [Abstract][Full Text] [Related]
3. 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine: an anticancer agent targeting hypoxic cells.
Seow HA; Penketh PG; Shyam K; Rockwell S; Sartorelli AC
Proc Natl Acad Sci U S A; 2005 Jun; 102(26):9282-7. PubMed ID: 15964988
[TBL] [Abstract][Full Text] [Related]
4. 9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1): a novel DNA-affinic bioreductive agent as chemosensitizer. I.
Papadopoulou MV; Ji M; Rao MK; Bloomer WD
Oncol Res; 1997; 9(5):249-57. PubMed ID: 9306432
[TBL] [Abstract][Full Text] [Related]
5. Nitracrine N-oxides: effects of variations in the nature of the side chain N-oxide on hypoxia-selective cytotoxicity.
Lee HH; Wilson WR; Denny WA
Anticancer Drug Des; 1999 Dec; 14(6):487-97. PubMed ID: 10834270
[TBL] [Abstract][Full Text] [Related]
6. Hypoxia-selective antitumor agents. 13. Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide.
Lee HH; Wilson WR; Ferry DM; van Zijl P; Pullen SM; Denny WA
J Med Chem; 1996 Jun; 39(13):2508-17. PubMed ID: 8691448
[TBL] [Abstract][Full Text] [Related]
7. 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-(methylamino)carbonylhydrazine (101M): a novel sulfonylhydrazine prodrug with broad-spectrum antineoplastic activity.
Finch RA; Shyam K; Penketh PG; Sartorelli AC
Cancer Res; 2001 Apr; 61(7):3033-8. PubMed ID: 11306484
[TBL] [Abstract][Full Text] [Related]
8. Interaction with hyperthermia of tetrachloroplatinum(II)(Nile blue)2 and tetrachloroplatinum(II)(neutral red)2 in EMT6 murine cells and the murine FSaIIC fibrosarcoma.
Herman TS; Teicher BA; Pfeffer MR; Khandekar VS; Korbut TT
Cancer Res; 1990 Jul; 50(13):3826-31. PubMed ID: 2354434
[TBL] [Abstract][Full Text] [Related]
9. Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns.
Bizanek R; Chowdary D; Arai H; Kasai M; Hughes CS; Sartorelli AC; Rockwell S; Tomasz M
Cancer Res; 1993 Nov; 53(21):5127-34. PubMed ID: 7693331
[TBL] [Abstract][Full Text] [Related]
10. Effects of RSR13 and oxygen on the cytotoxicity of cisplatin and carboplatin to EMT6 mouse mammary tumor cells in vitro and in vivo.
Donnelly ET; Kelley M; Rockwell S
Cancer Chemother Pharmacol; 2004 Jan; 53(1):43-50. PubMed ID: 14574460
[TBL] [Abstract][Full Text] [Related]
11. Porfiromycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro.
Keyes SR; Rockwell S; Sartorelli AC
Cancer Res; 1985 Aug; 45(8):3642-5. PubMed ID: 3926306
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamine.
Hay MP; Gamage SA; Kovacs MS; Pruijn FB; Anderson RF; Patterson AV; Wilson WR; Brown JM; Denny WA
J Med Chem; 2003 Jan; 46(1):169-82. PubMed ID: 12502371
[TBL] [Abstract][Full Text] [Related]
13. Antitumor 2-(aminocarbonyl)-1,2-bis(methylsulfonyl)-1-(2-chloroethyl)- hydrazines.
Shyam K; Penketh PG; Loomis RH; Rose WC; Sartorelli AC
J Med Chem; 1996 Feb; 39(3):796-801. PubMed ID: 8576923
[TBL] [Abstract][Full Text] [Related]
14. Influence of pH on the cytotoxicity of cisplatin in EMT6 mouse mammary tumor cells.
Laurencot CM; Kennedy KA
Oncol Res; 1995; 7(7-8):371-9. PubMed ID: 8747600
[TBL] [Abstract][Full Text] [Related]
15. Failure of 5-thio-D-glucose to alter cell survival in irradiated or unirradiated EMT6 tumors.
Rockwell S; Schulz RJ
Radiat Res; 1984 Dec; 100(3):527-35. PubMed ID: 6505142
[TBL] [Abstract][Full Text] [Related]
16. Correlation between drug uptake and selective toxicity of porfiromycin to hypoxic EMT6 cells.
Keyes SR; Rockwell S; Sartorelli AC
Cancer Res; 1987 Nov; 47(21):5654-7. PubMed ID: 3664473
[TBL] [Abstract][Full Text] [Related]
17. Modulation of the cytotoxicity of porfiromycin by dicoumarol in vitro and in vivo.
Rockwell S; Keyes SR; Sartorelli AC
Anticancer Res; 1989; 9(4):817-20. PubMed ID: 2479329
[TBL] [Abstract][Full Text] [Related]
18. Evaluation of hypoxic cell radio-sensitizers in terms of radio-sensitizing and repair-inhibiting potential. Dependency on p53 status of tumor cells and the effects on intratumor quiescent cells.
Masunaga S; Uto Y; Nagasawa H; Hori H; Nagata K; Suzuki M; Kinashi Y; Ono K
Anticancer Res; 2006; 26(2A):1261-70. PubMed ID: 16619533
[TBL] [Abstract][Full Text] [Related]
19. Effect of NDGA on beef heart mitochondria and EMT6 mouse mammary carcinoma cells.
Shi L; Pardini RS
Res Commun Mol Pathol Pharmacol; 1995 Nov; 90(2):235-54. PubMed ID: 8747792
[TBL] [Abstract][Full Text] [Related]
20. Nitro analogues of chlorambucil as potential hypoxia-selective anti-tumour drugs.
Palmer BD; Wilson WR; Denny WA
Anticancer Drug Des; 1990 Nov; 5(4):337-49. PubMed ID: 2291774
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]