BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

478 related articles for article (PubMed ID: 10074427)

  • 1. Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.
    Casamayor A; Torrance PD; Kobayashi T; Thorner J; Alessi DR
    Curr Biol; 1999 Feb; 9(4):186-97. PubMed ID: 10074427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity.
    Roelants FM; Torrance PD; Bezman N; Thorner J
    Mol Biol Cell; 2002 Sep; 13(9):3005-28. PubMed ID: 12221112
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential roles of PDK1- and PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9.
    Roelants FM; Torrance PD; Thorner J
    Microbiology (Reading); 2004 Oct; 150(Pt 10):3289-304. PubMed ID: 15470109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.
    Kobayashi T; Cohen P
    Biochem J; 1999 Apr; 339 ( Pt 2)(Pt 2):319-28. PubMed ID: 10191262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vivo role of the phosphate groove of PDK1 defined by knockin mutation.
    Collins BJ; Deak M; Murray-Tait V; Storey KG; Alessi DR
    J Cell Sci; 2005 Nov; 118(Pt 21):5023-34. PubMed ID: 16219676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Yeast 3-phosphoinositide-dependent protein kinase-1 (PDK1) orthologs Pkh1-3 differentially regulate phosphorylation of protein kinase A (PKA) and the protein kinase B (PKB)/S6K ortholog Sch9.
    Voordeckers K; Kimpe M; Haesendonckx S; Louwet W; Versele M; Thevelein JM
    J Biol Chem; 2011 Jun; 286(25):22017-27. PubMed ID: 21531713
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast.
    Sun Y; Taniguchi R; Tanoue D; Yamaji T; Takematsu H; Mori K; Fujita T; Kawasaki T; Kozutsumi Y
    Mol Cell Biol; 2000 Jun; 20(12):4411-9. PubMed ID: 10825204
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Ypk1 protein kinase signaling pathway is rewired and not essential for viability in Candida albicans.
    Ramírez-Zavala B; Krüger I; Wollner A; Schwanfelder S; Morschhäuser J
    PLoS Genet; 2023 Aug; 19(8):e1010890. PubMed ID: 37561787
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast.
    Inagaki M; Schmelzle T; Yamaguchi K; Irie K; Hall MN; Matsumoto K
    Mol Cell Biol; 1999 Dec; 19(12):8344-52. PubMed ID: 10567559
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
    Frödin M; Antal TL; Dümmler BA; Jensen CJ; Deak M; Gammeltoft S; Biondi RM
    EMBO J; 2002 Oct; 21(20):5396-407. PubMed ID: 12374740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The conserved Pkh-Ypk kinase cascade is required for endocytosis in yeast.
    deHart AK; Schnell JD; Allen DA; Hicke L
    J Cell Biol; 2002 Jan; 156(2):241-8. PubMed ID: 11807089
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
    Alessi DR; Deak M; Casamayor A; Caudwell FB; Morrice N; Norman DG; Gaffney P; Reese CB; MacDougall CN; Harbison D; Ashworth A; Bownes M
    Curr Biol; 1997 Oct; 7(10):776-89. PubMed ID: 9368760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositide-dependent kinase-1 orthologues from five eukaryotes are activated by the hydrophobic motif in AGC kinases.
    Silber J; Antal TL; Gammeltoft S; Rasmussen TE
    Biochem Biophys Res Commun; 2004 Sep; 321(4):823-7. PubMed ID: 15358101
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.
    Liu K; Zhang X; Lester RL; Dickson RC
    J Biol Chem; 2005 Jun; 280(24):22679-87. PubMed ID: 15840588
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.
    Biondi RM; Kieloch A; Currie RA; Deak M; Alessi DR
    EMBO J; 2001 Aug; 20(16):4380-90. PubMed ID: 11500365
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover.
    Luo G; Gruhler A; Liu Y; Jensen ON; Dickson RC
    J Biol Chem; 2008 Apr; 283(16):10433-44. PubMed ID: 18296441
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.
    Alessi DR; Kozlowski MT; Weng QP; Morrice N; Avruch J
    Curr Biol; 1998 Jan; 8(2):69-81. PubMed ID: 9427642
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
    Balendran A; Casamayor A; Deak M; Paterson A; Gaffney P; Currie R; Downes CP; Alessi DR
    Curr Biol; 1999 Apr; 9(8):393-404. PubMed ID: 10226025
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.
    Kobayashi T; Deak M; Morrice N; Cohen P
    Biochem J; 1999 Nov; 344 Pt 1(Pt 1):189-97. PubMed ID: 10548550
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252.
    Balendran A; Currie R; Armstrong CG; Avruch J; Alessi DR
    J Biol Chem; 1999 Dec; 274(52):37400-6. PubMed ID: 10601311
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.