BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

89 related articles for article (PubMed ID: 10101137)

  • 1. Possible involvement of P-glycoprotein in biliary excretion of CPT-11 in rats.
    Chu XY; Kato Y; Sugiyama Y
    Drug Metab Dispos; 1999 Apr; 27(4):440-1. PubMed ID: 10101137
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multiplicity of biliary excretion mechanisms for irinotecan, CPT-11, and its metabolites in rats.
    Chu XY; Kato Y; Sugiyama Y
    Cancer Res; 1997 May; 57(10):1934-8. PubMed ID: 9157988
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiplicity of biliary excretion mechanisms for the camptothecin derivative irinotecan (CPT-11), its metabolite SN-38, and its glucuronide: role of canalicular multispecific organic anion transporter and P-glycoprotein.
    Sugiyama Y; Kato Y; Chu X
    Cancer Chemother Pharmacol; 1998; 42 Suppl():S44-9. PubMed ID: 9750028
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multispecific organic anion transporter is responsible for the biliary excretion of the camptothecin derivative irinotecan and its metabolites in rats.
    Chu XY; Kato Y; Niinuma K; Sudo KI; Hakusui H; Sugiyama Y
    J Pharmacol Exp Ther; 1997 Apr; 281(1):304-14. PubMed ID: 9103511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biliary excretion mechanism of CPT-11 and its metabolites in humans: involvement of primary active transporters.
    Chu XY; Kato Y; Ueda K; Suzuki H; Niinuma K; Tyson CA; Weizer V; Dabbs JE; Froehlich R; Green CE; Sugiyama Y
    Cancer Res; 1998 Nov; 58(22):5137-43. PubMed ID: 9823324
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of P-glycoprotein modulator, cyclosporin A, on the gastrointestinal excretion of irinotecan and its metabolite SN-38 in rats.
    Arimori K; Kuroki N; Hidaka M; Iwakiri T; Yamsaki K; Okumura M; Ono H; Takamura N; Kikuchi M; Nakano M
    Pharm Res; 2003 Jun; 20(6):910-7. PubMed ID: 12817897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).
    Ishizuka H; Konno K; Naganuma H; Sasahara K; Kawahara Y; Niinuma K; Suzuki H; Sugiyama Y
    J Pharmacol Exp Ther; 1997 Mar; 280(3):1304-11. PubMed ID: 9067317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats.
    Sasabe H; Tsuji A; Sugiyama Y
    J Pharmacol Exp Ther; 1998 Mar; 284(3):1033-9. PubMed ID: 9495864
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide.
    Niinuma K; Takenaka O; Horie T; Kobayashi K; Kato Y; Suzuki H; Sugiyama Y
    J Pharmacol Exp Ther; 1997 Aug; 282(2):866-72. PubMed ID: 9262353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats.
    Masuda M; I'izuka Y; Yamazaki M; Nishigaki R; Kato Y; Ni'inuma K; Suzuki H; Sugiyama Y
    Cancer Res; 1997 Aug; 57(16):3506-10. PubMed ID: 9270020
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the transport of a cationic octapeptide, octreotide, in rat bile canalicular membrane: possible involvement of P-glycoprotein.
    Yamada T; Kato Y; Kusuhara H; Lemaire M; Sugiyama Y
    Biol Pharm Bull; 1998 Aug; 21(8):874-8. PubMed ID: 9743261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter.
    Yamazaki M; Akiyama S; Ni'inuma K; Nishigaki R; Sugiyama Y
    Drug Metab Dispos; 1997 Oct; 25(10):1123-9. PubMed ID: 9321514
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.
    Paulusma CC; van Geer MA; Evers R; Heijn M; Ottenhoff R; Borst P; Oude Elferink RP
    Biochem J; 1999 Mar; 338 ( Pt 2)(Pt 2):393-401. PubMed ID: 10024515
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biliary excretion of 17beta-estradiol 17beta-D-glucuronide is predominantly mediated by cMOAT/MRP2.
    Morikawa A; Goto Y; Suzuki H; Hirohashi T; Sugiyama Y
    Pharm Res; 2000 May; 17(5):546-52. PubMed ID: 10888306
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Primary active transport of peptidic endothelin antagonists by rat hepatic canalicular membrane.
    Akhteruzzaman S; Kato Y; Hisaka A; Sugiyama Y
    J Pharmacol Exp Ther; 1999 Feb; 288(2):575-81. PubMed ID: 9918561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trandolaprilat, an angiotensin-converting enzyme inhibitor, is not excreted in bile via an ATP-dependent active transporter (cMOAT).
    Shionoiri H; Takasaki I; Minamisawa K; Ishizuka H; Konno K; Naganuma H; Sasahara K; Kawahara Y
    Hypertens Res; 2001 May; 24(3):235-40. PubMed ID: 11409646
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biliary excretion of irinotecan and its metabolites.
    Itoh T; Takemoto I; Itagaki S; Sasaki K; Hirano T; Iseki K
    J Pharm Pharm Sci; 2004 Jan; 7(1):13-8. PubMed ID: 15144730
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carrier-mediated hepatobiliary transport of a novel antifolate, N-[4-[(2,4-dianninopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-homoglutamic acid, in rats.
    Han YH; Kato Y; Watanabe Y; Terao K; Asoh Y; Sugiyama Y
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):394-400. PubMed ID: 11259322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Species differences in the transport activity for organic anions across the bile canalicular membrane.
    Ishizuka H; Konno K; Shiina T; Naganuma H; Nishimura K; Ito K; Suzuki H; Sugiyama Y
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1324-30. PubMed ID: 10454510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loperamide inhibits the biliary excretion of irinotecan (CPT-11) in the rat isolated perfused liver.
    Tobin PJ; Hong Y; Seale JP; Rivory LP; McLachlan AJ
    J Pharm Pharmacol; 2005 Jan; 57(1):39-45. PubMed ID: 15638991
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.