BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 101303)

  • 1. Correlation of tubulin-binding and antitumor activities of podophyllotoxin analogs.
    Kelleher JK
    Cancer Treat Rep; 1978 Oct; 62(10):1443-7. PubMed ID: 101303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tubulin binding affinities of podophyllotoxin and colchicine analogues.
    Kelleher JK
    Mol Pharmacol; 1977 Mar; 13(2):232-41. PubMed ID: 854021
    [No Abstract]   [Full Text] [Related]  

  • 3. Applying linear interaction energy method for binding affinity calculations of podophyllotoxin analogues with tubulin using continuum solvent model and prediction of cytotoxic activity.
    Alam MA; Naik PK
    J Mol Graph Model; 2009; 27(8):930-43. PubMed ID: 19286405
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2007 Nov; 50(24):6059-66. PubMed ID: 17973361
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of novel thiocolchicine-podophyllotoxin conjugates.
    Passarella D; Peretto B; Blasco y Yepes R; Cappelletti G; Cartelli D; Ronchi C; Snaith J; Fontana G; Danieli B; Borlak J
    Eur J Med Chem; 2010 Jan; 45(1):219-26. PubMed ID: 19880222
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antimitotic and antitubulin activity of the tumor inhibitor steganacin.
    Wang RW; Rebhum LI; Kupchan SM
    Cancer Res; 1977 Sep; 37(9):3071-9. PubMed ID: 560248
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxalone and lactone moieties of podophyllotoxin exhibit properties of both the B and C rings of colchicine in its binding with tubulin.
    Gupta S; Das L; Datta AB; Poddar A; Janik ME; Bhattacharyya B
    Biochemistry; 2006 May; 45(20):6467-75. PubMed ID: 16700557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of action of E7010, an orally active sulfonamide antitumor agent: inhibition of mitosis by binding to the colchicine site of tubulin.
    Yoshimatsu K; Yamaguchi A; Yoshino H; Koyanagi N; Kitoh K
    Cancer Res; 1997 Aug; 57(15):3208-13. PubMed ID: 9242451
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Linkages in tubulin-colchicine functions: the role of the ring C (C') oxygens and ring B in the controls.
    Pérez-Ramírez B; Gorbunoff MJ; Timasheff SN
    Biochemistry; 1998 Feb; 37(6):1646-61. PubMed ID: 9484236
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antitumor agents. 178. Synthesis and biological evaluation of substituted 2-aryl-1,8-naphthyridin-4(1H)-ones as antitumor agents that inhibit tubulin polymerization.
    Chen K; Kuo SC; Hsieh MC; Mauger A; Lin CM; Hamel E; Lee KH
    J Med Chem; 1997 Sep; 40(19):3049-56. PubMed ID: 9301667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binding of colchicine to beef brain tubulin: influence of methodology on binding constants.
    Luyckx M; Brunet C; Cazin M
    Methods Find Exp Clin Pharmacol; 1984 Nov; 6(11):679-84. PubMed ID: 6530906
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microtubules and axoplasmic transport. Inhibition of transport by podophyllotoxin: an interaction with microtubule protein.
    Paulson JC; McClure WO
    J Cell Biol; 1975 Nov; 67(2PT.1):461-7. PubMed ID: 53233
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
    Perchellet EM; Ladesich JB; Magill MJ; Chen Y; Hua DH; Perchellet JP
    Anticancer Drugs; 1999 Jun; 10(5):489-504. PubMed ID: 10477169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The interaction of colchicine and some related alkaloids with rat brain tubulin.
    McClure WO; Paulson JC
    Mol Pharmacol; 1977 May; 13(3):560-75. PubMed ID: 559920
    [No Abstract]   [Full Text] [Related]  

  • 15. Comparison of 1,2-dihydropyrido[3,4-b]pyrazines (1-deaza-7,8-dihydropteridines) with several other inhibitors of mitosis.
    Bowdon BJ; Waud WR; Wheeler GP; Hain R; Dansby L; Temple C
    Cancer Res; 1987 Mar; 47(6):1621-6. PubMed ID: 3815360
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.
    Gastpar R; Goldbrunner M; Marko D; von Angerer E
    J Med Chem; 1998 Dec; 41(25):4965-72. PubMed ID: 9836614
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Chen K; Kuo SC; Hsieh MC; Mauger A; Lin CM; Hamel E; Lee KH
    J Med Chem; 1997 Jul; 40(14):2266-75. PubMed ID: 9216846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain.
    Zhao W; He L; Xiang TL; Tang YJ
    Eur J Med Chem; 2019 May; 170():73-86. PubMed ID: 30878833
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Requirements for P-glycoprotein recognition based on structure-activity relationships in the podophyllotoxin series.
    Etievant C; Schambel P; Guminski Y; Barret JM; Imbert T; Hill BT
    Anticancer Drug Des; 1998 Jun; 13(4):317-36. PubMed ID: 9627671
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of [3H]mebendazole binding to tubulin by structurally diverse microtubule inhibitors which interact at the colchicine binding site.
    Russell GJ; Lacey E
    Biochem Mol Biol Int; 1995 May; 35(6):1153-9. PubMed ID: 7492951
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.