243 related articles for article (PubMed ID: 10194549)
1. Differential effects of UCN-01, staurosporine and CGP 41 251 on cell cycle progression and CDC2/cyclin B1 regulation in A431 cells synchronized at M phase by nocodazole.
Akiyama T; Shimizu M; Okabe M; Tamaoki T; Akinaga S
Anticancer Drugs; 1999 Jan; 10(1):67-78. PubMed ID: 10194549
[TBL] [Abstract][Full Text] [Related]
2. UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.
Wang Q; Fan S; Eastman A; Worland PJ; Sausville EA; O'Connor PM
J Natl Cancer Inst; 1996 Jul; 88(14):956-65. PubMed ID: 8667426
[TBL] [Abstract][Full Text] [Related]
3. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
[TBL] [Abstract][Full Text] [Related]
4. Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.
Ling YH; Tornos C; Perez-Soler R
J Biol Chem; 1998 Jul; 273(30):18984-91. PubMed ID: 9668078
[TBL] [Abstract][Full Text] [Related]
5. Effect of UCN-01, a selective inhibitor of protein kinase C, on the cell-cycle distribution of human epidermoid carcinoma, A431 cells.
Akinaga S; Nomura K; Gomi K; Okabe M
Cancer Chemother Pharmacol; 1994; 33(4):273-80. PubMed ID: 7506638
[TBL] [Abstract][Full Text] [Related]
6. G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation.
Akiyama T; Sugiyama K; Shimizu M; Tamaoki T; Akinaga S
Jpn J Cancer Res; 1999 Dec; 90(12):1364-72. PubMed ID: 10665655
[TBL] [Abstract][Full Text] [Related]
7. Altered sensitivity of deoxyadenosine-resistant mouse leukemia L1210 cells to apoptosis induced by 7-hydroxystaurosporine.
Somerville L; Cory JG
Int J Oncol; 2000 Oct; 17(4):797-803. PubMed ID: 10995894
[TBL] [Abstract][Full Text] [Related]
8. A p21(waf1)-independent pathway for inhibitory phosphorylation of cyclin-dependent kinase p34(cdc2) and concomitant G(2)/M arrest by the chemopreventive flavonoid apigenin.
McVean M; Weinberg WC; Pelling JC
Mol Carcinog; 2002 Jan; 33(1):36-43. PubMed ID: 11807956
[TBL] [Abstract][Full Text] [Related]
9. Treatment of human glioblastoma cells with the staurosporine derivative CGP 41251 inhibits CDC2 and CDK2 kinase activity and increases radiation sensitivity.
Begemann M; Kashimawo SA; Heitjan DF; Schiff PB; Bruce JN; Weinstein IB
Anticancer Res; 1998; 18(4A):2275-82. PubMed ID: 9703866
[TBL] [Abstract][Full Text] [Related]
10. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
Patel V; Lahusen T; Leethanakul C; Igishi T; Kremer M; Quintanilla-Martinez L; Ensley JF; Sausville EA; Gutkind JS; Senderowicz AM
Clin Cancer Res; 2002 Nov; 8(11):3549-60. PubMed ID: 12429646
[TBL] [Abstract][Full Text] [Related]
11. Flavopiridol, a cyclin-dependent kinase inhibitor, prevents spindle inhibitor-induced endoreduplication in human cancer cells.
Motwani M; Li X; Schwartz GK
Clin Cancer Res; 2000 Mar; 6(3):924-32. PubMed ID: 10741717
[TBL] [Abstract][Full Text] [Related]
12. Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine).
Sugiyama K; Akiyama T; Shimizu M; Tamaoki T; Courage C; Gescher A; Akinaga S
Cancer Res; 1999 Sep; 59(17):4406-12. PubMed ID: 10485490
[TBL] [Abstract][Full Text] [Related]
13. A brief staurosporine treatment of mitotic cells triggers premature exit from mitosis and polyploid cell formation.
Hall LL; Th'ng JP; Guo XW; Teplitz RL; Bradbury EM
Cancer Res; 1996 Aug; 56(15):3551-9. PubMed ID: 8758926
[TBL] [Abstract][Full Text] [Related]
14. 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53.
Shao RG; Shimizu T; Pommier Y
Exp Cell Res; 1997 Aug; 234(2):388-97. PubMed ID: 9260909
[TBL] [Abstract][Full Text] [Related]
15. Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells.
Shao RG; Cao CX; Pommier Y
Acta Pharmacol Sin; 2004 Jun; 25(6):756-62. PubMed ID: 15169628
[TBL] [Abstract][Full Text] [Related]
16. Role of cyclin B1/Cdc2 up-regulation in the development of mitotic prometaphase arrest in human breast cancer cells treated with nocodazole.
Choi HJ; Fukui M; Zhu BT
PLoS One; 2011; 6(8):e24312. PubMed ID: 21918689
[TBL] [Abstract][Full Text] [Related]
17. Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45.
Zhan Q; Antinore MJ; Wang XW; Carrier F; Smith ML; Harris CC; Fornace AJ
Oncogene; 1999 May; 18(18):2892-900. PubMed ID: 10362260
[TBL] [Abstract][Full Text] [Related]
18. Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines.
Lee SI; Brown MK; Eastman A
Biochem Pharmacol; 1999 Dec; 58(11):1713-21. PubMed ID: 10571245
[TBL] [Abstract][Full Text] [Related]
19. Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
Dash BC; El-Deiry WS
Mol Cell Biol; 2005 Apr; 25(8):3364-87. PubMed ID: 15798220
[TBL] [Abstract][Full Text] [Related]
20. Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II.
Hutchins JR; Dikovskaya D; Clarke PR
Mol Biol Cell; 2003 Oct; 14(10):4003-14. PubMed ID: 14517314
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
