BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

466 related articles for article (PubMed ID: 10195180)

  • 1. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons.
    Williamson TL; Cleveland DW
    Nat Neurosci; 1999 Jan; 2(1):50-6. PubMed ID: 10195180
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice.
    Borchelt DR; Wong PC; Becher MW; Pardo CA; Lee MK; Xu ZS; Thinakaran G; Jenkins NA; Copeland NG; Sisodia SS; Cleveland DW; Price DL; Hoffman PN
    Neurobiol Dis; 1998 Jul; 5(1):27-35. PubMed ID: 9702785
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene.
    Sasaki S; Warita H; Abe K; Iwata M
    Acta Neuropathol; 2005 Jul; 110(1):48-56. PubMed ID: 15920660
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex.
    Zhang F; Ström AL; Fukada K; Lee S; Hayward LJ; Zhu H
    J Biol Chem; 2007 Jun; 282(22):16691-9. PubMed ID: 17403682
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport.
    Shi P; Ström AL; Gal J; Zhu H
    Biochim Biophys Acta; 2010 Sep; 1802(9):707-16. PubMed ID: 20510358
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deficits in axonal transport precede ALS symptoms in vivo.
    Bilsland LG; Sahai E; Kelly G; Golding M; Greensmith L; Schiavo G
    Proc Natl Acad Sci U S A; 2010 Nov; 107(47):20523-8. PubMed ID: 21059924
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant.
    Williamson TL; Bruijn LI; Zhu Q; Anderson KL; Anderson SD; Julien JP; Cleveland DW
    Proc Natl Acad Sci U S A; 1998 Aug; 95(16):9631-6. PubMed ID: 9689132
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.
    De Vos KJ; Chapman AL; Tennant ME; Manser C; Tudor EL; Lau KF; Brownlees J; Ackerley S; Shaw PJ; McLoughlin DM; Shaw CE; Leigh PN; Miller CCJ; Grierson AJ
    Hum Mol Genet; 2007 Nov; 16(22):2720-2728. PubMed ID: 17725983
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation.
    Zhang B; Tu P; Abtahian F; Trojanowski JQ; Lee VM
    J Cell Biol; 1997 Dec; 139(5):1307-15. PubMed ID: 9382875
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels.
    Moller A; Bauer CS; Cohen RN; Webster CP; De Vos KJ
    Hum Mol Genet; 2017 Dec; 26(23):4668-4679. PubMed ID: 28973175
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ALS: a disease of motor neurons and their nonneuronal neighbors.
    Boillée S; Vande Velde C; Cleveland DW
    Neuron; 2006 Oct; 52(1):39-59. PubMed ID: 17015226
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
    Clement AM; Nguyen MD; Roberts EA; Garcia ML; Boillée S; Rule M; McMahon AP; Doucette W; Siwek D; Ferrante RJ; Brown RH; Julien JP; Goldstein LS; Cleveland DW
    Science; 2003 Oct; 302(5642):113-7. PubMed ID: 14526083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1.
    Bruijn LI; Houseweart MK; Kato S; Anderson KL; Anderson SD; Ohama E; Reaume AG; Scott RW; Cleveland DW
    Science; 1998 Sep; 281(5384):1851-4. PubMed ID: 9743498
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase.
    Couillard-Després S; Meier J; Julien JP
    Neurobiol Dis; 2000 Aug; 7(4):462-70. PubMed ID: 10964615
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice.
    Kieran D; Hafezparast M; Bohnert S; Dick JR; Martin J; Schiavo G; Fisher EM; Greensmith L
    J Cell Biol; 2005 May; 169(4):561-7. PubMed ID: 15911875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Progressive spinal axonal degeneration and slowness in ALS2-deficient mice.
    Yamanaka K; Miller TM; McAlonis-Downes M; Chun SJ; Cleveland DW
    Ann Neurol; 2006 Jul; 60(1):95-104. PubMed ID: 16802286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intracellular conformational alterations of mutant SOD1 and the implications for fALS-associated SOD1 mutant induced motor neuron cell death.
    Zhang F; Zhu H
    Biochim Biophys Acta; 2006 Mar; 1760(3):404-14. PubMed ID: 16431026
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-throughput quantitative analysis of axonal transport in cultured neurons from SOD1
    Otomo A; Ono S; Sato K; Mitsui S; Shimakura K; Kimura H; Hadano S
    Neurosci Res; 2022 Jan; 174():46-52. PubMed ID: 34352295
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.
    Fujisawa T; Homma K; Yamaguchi N; Kadowaki H; Tsuburaya N; Naguro I; Matsuzawa A; Takeda K; Takahashi Y; Goto J; Tsuji S; Nishitoh H; Ichijo H
    Ann Neurol; 2012 Nov; 72(5):739-49. PubMed ID: 23280792
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1.
    Kong J; Xu Z
    J Neurosci; 1998 May; 18(9):3241-50. PubMed ID: 9547233
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.