130 related articles for article (PubMed ID: 10196170)
1. Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents.
Gibson S; Widmann C; Johnson GL
J Biol Chem; 1999 Apr; 274(16):10916-22. PubMed ID: 10196170
[TBL] [Abstract][Full Text] [Related]
2. Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells.
Shiah SG; Chuang SE; Kuo ML
Mol Pharmacol; 2001 Feb; 59(2):254-62. PubMed ID: 11160861
[TBL] [Abstract][Full Text] [Related]
3. MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis.
Widmann C; Gerwins P; Johnson NL; Jarpe MB; Johnson GL
Mol Cell Biol; 1998 Apr; 18(4):2416-29. PubMed ID: 9528810
[TBL] [Abstract][Full Text] [Related]
4. MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage.
Bild AH; Mendoza FJ; Gibson EM; Huang M; Villanueva J; Garrington TP; Jove R; Johnson GL; Gibson SB
Oncogene; 2002 Sep; 21(43):6649-56. PubMed ID: 12242663
[TBL] [Abstract][Full Text] [Related]
5. MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release.
Gibson EM; Henson ES; Villanueva J; Gibson SB
J Biol Chem; 2002 Mar; 277(12):10573-80. PubMed ID: 11756439
[TBL] [Abstract][Full Text] [Related]
6. Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.
Widmann C; Johnson NL; Gardner AM; Smith RJ; Johnson GL
Oncogene; 1997 Nov; 15(20):2439-47. PubMed ID: 9395240
[TBL] [Abstract][Full Text] [Related]
7. Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells.
Blagosklonny MV; Chuman Y; Bergan RC; Fojo T
Leukemia; 1999 Jul; 13(7):1028-36. PubMed ID: 10400418
[TBL] [Abstract][Full Text] [Related]
8. MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.
Yujiri T; Fanger GR; Garrington TP; Schlesinger TK; Gibson S; Johnson GL
J Biol Chem; 1999 Apr; 274(18):12605-10. PubMed ID: 10212239
[TBL] [Abstract][Full Text] [Related]
9. The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways.
Boldt S; Weidle UH; Kolch W
Exp Cell Res; 2003 Feb; 283(1):80-90. PubMed ID: 12565821
[TBL] [Abstract][Full Text] [Related]
10. MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption.
Kwan R; Burnside J; Kurosaki T; Cheng G
Mol Cell Biol; 2001 Nov; 21(21):7183-90. PubMed ID: 11585901
[TBL] [Abstract][Full Text] [Related]
11. Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase.
Srivastava RK; Srivastava AR; Korsmeyer SJ; Nesterova M; Cho-Chung YS; Longo DL
Mol Cell Biol; 1998 Jun; 18(6):3509-17. PubMed ID: 9584191
[TBL] [Abstract][Full Text] [Related]
12. Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively.
Kolomeichuk SN; Terrano DT; Lyle CS; Sabapathy K; Chambers TC
FEBS J; 2008 Apr; 275(8):1889-99. PubMed ID: 18341588
[TBL] [Abstract][Full Text] [Related]
13. MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondria.
Mendoza FJ; Henson ES; Gibson SB
Biochem Biophys Res Commun; 2005 Jun; 331(4):1089-98. PubMed ID: 15882989
[TBL] [Abstract][Full Text] [Related]
14. Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation.
Figueroa-Masot XA; Hetman M; Higgins MJ; Kokot N; Xia Z
J Neurosci; 2001 Jul; 21(13):4657-67. PubMed ID: 11425893
[TBL] [Abstract][Full Text] [Related]
15. Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis.
Pardo OE; Arcaro A; Salerno G; Raguz S; Downward J; Seckl MJ
J Biol Chem; 2002 Apr; 277(14):12040-6. PubMed ID: 11815602
[TBL] [Abstract][Full Text] [Related]
16. "Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.
Fang G; Chang BS; Kim CN; Perkins C; Thompson CB; Bhalla KN
Cancer Res; 1998 Aug; 58(15):3202-8. PubMed ID: 9699642
[TBL] [Abstract][Full Text] [Related]
17. Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways.
Wang TH; Wang HS; Ichijo H; Giannakakou P; Foster JS; Fojo T; Wimalasena J
J Biol Chem; 1998 Feb; 273(9):4928-36. PubMed ID: 9478937
[TBL] [Abstract][Full Text] [Related]
18. Human glutathione S-transferase P1 suppresses MEKK1-mediated apoptosis by regulating MEKK1 kinase activity in HEK293 cells.
Zhao X; Fan Y; Shen J; Wu Y; Yin Z
Mol Cells; 2006 Jun; 21(3):395-400. PubMed ID: 16819303
[TBL] [Abstract][Full Text] [Related]
19. JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents.
Besirli CG; Johnson EM
J Biol Chem; 2003 Jun; 278(25):22357-66. PubMed ID: 12684520
[TBL] [Abstract][Full Text] [Related]
20. Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosis.
Shimada K; Matsuyoshi S; Nakamura M; Ishida E; Kishi M; Konishi N
Carcinogenesis; 2004 Jul; 25(7):1089-97. PubMed ID: 15001534
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]