These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 10196170)

  • 1. Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents.
    Gibson S; Widmann C; Johnson GL
    J Biol Chem; 1999 Apr; 274(16):10916-22. PubMed ID: 10196170
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells.
    Shiah SG; Chuang SE; Kuo ML
    Mol Pharmacol; 2001 Feb; 59(2):254-62. PubMed ID: 11160861
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis.
    Widmann C; Gerwins P; Johnson NL; Jarpe MB; Johnson GL
    Mol Cell Biol; 1998 Apr; 18(4):2416-29. PubMed ID: 9528810
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage.
    Bild AH; Mendoza FJ; Gibson EM; Huang M; Villanueva J; Garrington TP; Jove R; Johnson GL; Gibson SB
    Oncogene; 2002 Sep; 21(43):6649-56. PubMed ID: 12242663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release.
    Gibson EM; Henson ES; Villanueva J; Gibson SB
    J Biol Chem; 2002 Mar; 277(12):10573-80. PubMed ID: 11756439
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.
    Widmann C; Johnson NL; Gardner AM; Smith RJ; Johnson GL
    Oncogene; 1997 Nov; 15(20):2439-47. PubMed ID: 9395240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells.
    Blagosklonny MV; Chuman Y; Bergan RC; Fojo T
    Leukemia; 1999 Jul; 13(7):1028-36. PubMed ID: 10400418
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.
    Yujiri T; Fanger GR; Garrington TP; Schlesinger TK; Gibson S; Johnson GL
    J Biol Chem; 1999 Apr; 274(18):12605-10. PubMed ID: 10212239
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways.
    Boldt S; Weidle UH; Kolch W
    Exp Cell Res; 2003 Feb; 283(1):80-90. PubMed ID: 12565821
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption.
    Kwan R; Burnside J; Kurosaki T; Cheng G
    Mol Cell Biol; 2001 Nov; 21(21):7183-90. PubMed ID: 11585901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase.
    Srivastava RK; Srivastava AR; Korsmeyer SJ; Nesterova M; Cho-Chung YS; Longo DL
    Mol Cell Biol; 1998 Jun; 18(6):3509-17. PubMed ID: 9584191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively.
    Kolomeichuk SN; Terrano DT; Lyle CS; Sabapathy K; Chambers TC
    FEBS J; 2008 Apr; 275(8):1889-99. PubMed ID: 18341588
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondria.
    Mendoza FJ; Henson ES; Gibson SB
    Biochem Biophys Res Commun; 2005 Jun; 331(4):1089-98. PubMed ID: 15882989
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation.
    Figueroa-Masot XA; Hetman M; Higgins MJ; Kokot N; Xia Z
    J Neurosci; 2001 Jul; 21(13):4657-67. PubMed ID: 11425893
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis.
    Pardo OE; Arcaro A; Salerno G; Raguz S; Downward J; Seckl MJ
    J Biol Chem; 2002 Apr; 277(14):12040-6. PubMed ID: 11815602
    [TBL] [Abstract][Full Text] [Related]  

  • 16. "Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.
    Fang G; Chang BS; Kim CN; Perkins C; Thompson CB; Bhalla KN
    Cancer Res; 1998 Aug; 58(15):3202-8. PubMed ID: 9699642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways.
    Wang TH; Wang HS; Ichijo H; Giannakakou P; Foster JS; Fojo T; Wimalasena J
    J Biol Chem; 1998 Feb; 273(9):4928-36. PubMed ID: 9478937
    [TBL] [Abstract][Full Text] [Related]  

  • 18. JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents.
    Besirli CG; Johnson EM
    J Biol Chem; 2003 Jun; 278(25):22357-66. PubMed ID: 12684520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosis.
    Shimada K; Matsuyoshi S; Nakamura M; Ishida E; Kishi M; Konishi N
    Carcinogenesis; 2004 Jul; 25(7):1089-97. PubMed ID: 15001534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals.
    Widmann C; Gibson S; Johnson GL
    J Biol Chem; 1998 Mar; 273(12):7141-7. PubMed ID: 9507028
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.