BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 10197604)

  • 1. Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: formation of stable DNA adducts and absence of a detectable increase in apurinic sites.
    Melendez-Colon VJ; Luch A; Seidel A; Baird WM
    Cancer Res; 1999 Apr; 59(7):1412-6. PubMed ID: 10197604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures.
    Melendez-Colon VJ; Luch A; Seidel A; Baird WM
    Chem Res Toxicol; 2000 Jan; 13(1):10-7. PubMed ID: 10649961
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene.
    Luch A; Coffing SL; Tang YM; Schneider A; Soballa V; Greim H; Jefcoate CR; Seidel A; Greenlee WF; Baird WM; Doehmer J
    Chem Res Toxicol; 1998 Jun; 11(6):686-95. PubMed ID: 9625737
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The K-region trans-8,9-diol does not significantly contribute as an intermediate in the metabolic activation of dibenzo[a,l]pyrene to DNA-binding metabolites by human cytochrome P450 1A1 or 1B1.
    Luch A; Kishiyama S; Seidel A; Doehmer J; Greim H; Baird WM
    Cancer Res; 1999 Sep; 59(18):4603-9. PubMed ID: 10493514
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo[a,l]pyrene or its diol epoxides.
    Melendez-Colon VJ; Smith CA; Seidel A; Luch A; Platt KL; Baird WM
    Proc Natl Acad Sci U S A; 1997 Dec; 94(25):13542-7. PubMed ID: 9391062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A quantitative comparison of dibenzo[a,l]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes.
    King LC; Adams L; Allison J; Kohan MJ; Nelson G; Desai D; Amin S; Ross JA
    Mol Carcinog; 1999 Oct; 26(2):74-82. PubMed ID: 10506751
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and quantification of the depurinating DNA adducts formed in mouse skin treated with dibenzo[a,l]pyrene (DB[a,l]P) or its metabolites and in rat mammary gland treated with DB[a,l]P.
    Cavalieri EL; Rogan EG; Li KM; Todorovic R; Ariese F; Jankowiak R; Grubor N; Small GJ
    Chem Res Toxicol; 2005 Jun; 18(6):976-83. PubMed ID: 15962932
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.
    Nesnow S; Davis C; Padgett W; George M; Lambert G; Meyers F; Allison J; Adams L; King LC
    Chem Res Toxicol; 1998 Dec; 11(12):1596-607. PubMed ID: 9860506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stereoselective activation of dibenzo[a,l]pyrene and its trans-11,12-dihydrodiol to fjord region 11,12-diol 13,14-epoxides in a human mammary carcinoma MCF-7 cell-mediated V79 cell mutation assay.
    Ralston SL; Coffing SL; Seidel A; Luch A; Platt KL; Baird WM
    Chem Res Toxicol; 1997 Jun; 10(6):687-93. PubMed ID: 9208176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and quantitation of dibenzo[a,l]pyrene--DNA adducts formed by rat liver microsomes in vitro: preponderance of depurinating adducts.
    Li KM; Todorovic R; Rogan EG; Cavalieri EL; Ariese F; Suh M; Jankowiak R; Small GJ
    Biochemistry; 1995 Jun; 34(25):8043-9. PubMed ID: 7794917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and quantification of stable DNA adducts formed from dibenzo[a,l]pyrene or its metabolites in vitro and in mouse skin and rat mammary gland.
    Todorovic R; Devanesan P; Rogan E; Cavalieri E
    Chem Res Toxicol; 2005 Jun; 18(6):984-90. PubMed ID: 15962933
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The potent carcinogen dibenzo[a,l]pyrene is metabolically activated to fjord-region 11,12-diol 13,14-epoxides in human mammary carcinoma MCF-7 cell cultures.
    Ralston SL; Lau HH; Seidel A; Luch A; Platt KL; Baird WM
    Cancer Res; 1994 Feb; 54(4):887-90. PubMed ID: 8313376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytochrome P450 1B1 determines susceptibility to dibenzo[a,l]pyrene-induced tumor formation.
    Buters JT; Mahadevan B; Quintanilla-Martinez L; Gonzalez FJ; Greim H; Baird WM; Luch A
    Chem Res Toxicol; 2002 Sep; 15(9):1127-35. PubMed ID: 12230405
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites.
    Melendez-Colon VJ; Luch A; Seidel A; Baird WM
    Carcinogenesis; 1999 Oct; 20(10):1885-91. PubMed ID: 10506100
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.
    Luch A; Schober W; Soballa VJ; Raab G; Greim H; Jacob J; Doehmer J; Seidel A
    Chem Res Toxicol; 1999 Apr; 12(4):353-64. PubMed ID: 10207125
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of the morphological transforming activities of dibenzo[a,l]pyrene and benzo[a]pyrene in C3H10T1/2CL8 cells and characterization of the dibenzo[a,l]pyrene-DNA adducts.
    Nesnow S; Davis C; Nelson G; Ross JA; Allison J; Adams L; King LC
    Carcinogenesis; 1997 Oct; 18(10):1973-8. PubMed ID: 9364008
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel method for the isolation and identification of stable DNA adducts formed by Dibenzo[a,l]pyrene and Dibenzo[a,l]pyrene 11, 12-dihydrodiol 13,14-epoxides in vitro.
    Devanesan P; Ariese F; Jankowiak R; Small GJ; Rogan EG; Cavalieri EL
    Chem Res Toxicol; 1999 Sep; 12(9):796-801. PubMed ID: 10490500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure, conformations, and repair of DNA adducts from dibenzo[a, l]pyrene: 32P-postlabeling and fluorescence studies.
    Jankowiak R; Ariese F; Hewer A; Luch A; Zamzow D; Hughes NC; Phillips D; Seidel A; Platt KL; Oesch F; Small GJ
    Chem Res Toxicol; 1998 Jun; 11(6):674-85. PubMed ID: 9625736
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The molecular etiology and prevention of estrogen-initiated cancers: Ockham's Razor: Pluralitas non est ponenda sine necessitate. Plurality should not be posited without necessity.
    Cavalieri E; Rogan E
    Mol Aspects Med; 2014 Apr; 36():1-55. PubMed ID: 23994691
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.
    Einolf HJ; Story WT; Marcus CB; Larsen MC; Jefcoate CR; Greenlee WF; Yagi H; Jerina DM; Amin S; Park SS; Gelboin HV; Baird WM
    Chem Res Toxicol; 1997 May; 10(5):609-17. PubMed ID: 9168260
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.