112 related articles for article (PubMed ID: 10205619)
1. Studies on the stability of trans-alpha-acetoxytamoxifen in Sprague-Dawley female rat liver slices, homogenate and subcellular fractions including microsomes and mitochondria.
Jordan CG; Brown K; Beedham C; Brown JE
Int J Pharm; 1999 Jan; 177(2):259-70. PubMed ID: 10205619
[TBL] [Abstract][Full Text] [Related]
2. Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts.
Boocock DJ; Maggs JL; Brown K; White IN; Park BK
Carcinogenesis; 2000 Oct; 21(10):1851-8. PubMed ID: 11023543
[TBL] [Abstract][Full Text] [Related]
3. 4-Hydroxytamoxifen gives DNA adducts by chemical activation, but not in rat liver cells.
Osborne MR; Davis W; Hewer AJ; Hardcastle IR; Phillips DH
Chem Res Toxicol; 1999 Feb; 12(2):151-8. PubMed ID: 10027792
[TBL] [Abstract][Full Text] [Related]
4. Identification of tamoxifen-DNA adducts formed by alpha-sulfate tamoxifen and alpha-acetoxytamoxifen.
Dasaradhi L; Shibutani S
Chem Res Toxicol; 1997 Feb; 10(2):189-96. PubMed ID: 9049430
[TBL] [Abstract][Full Text] [Related]
5. Tamoxifen-DNA adducts formed by alpha-acetoxytamoxifen N-oxide.
Umemoto A; Monden Y; Komaki K; Suwa M; Kanno Y; Suzuki M; Lin CX; Ueyama Y; Momen MA; Ravindernath A; Shibutani S
Chem Res Toxicol; 1999 Nov; 12(11):1083-9. PubMed ID: 10563834
[TBL] [Abstract][Full Text] [Related]
6. Determination of DNA damage in F344 rats induced by geometric isomers of tamoxifen and analogues.
Brown K; Brown JE; Martin EA; Smith LL; White IN
Chem Res Toxicol; 1998 May; 11(5):527-34. PubMed ID: 9585484
[TBL] [Abstract][Full Text] [Related]
7. alpha-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes.
Phillips DH; Carmichael PL; Hewer A; Cole KJ; Poon GK
Cancer Res; 1994 Nov; 54(21):5518-22. PubMed ID: 7923188
[TBL] [Abstract][Full Text] [Related]
8. Quantification of tamoxifen DNA adducts using on-line sample preparation and HPLC-electrospray ionization tandem mass spectrometry.
Gamboa da Costa G; Marques MM; Beland FA; Freeman JP; Churchwell MI; Doerge DR
Chem Res Toxicol; 2003 Mar; 16(3):357-66. PubMed ID: 12641436
[TBL] [Abstract][Full Text] [Related]
9. Resolution of alpha-hydroxytamoxifen; R-isomer forms more DNA adducts in rat liver cells.
Osborne MR; Hewer A; Phillips DH
Chem Res Toxicol; 2001 Jul; 14(7):888-93. PubMed ID: 11453736
[TBL] [Abstract][Full Text] [Related]
10. Tamoxifen metabolism in rat liver microsomes: identification of a dimeric metabolite derived from free radical intermediates by liquid chromatography/mass spectrometry.
Jones RM; Yuan ZX; Lim CK
Rapid Commun Mass Spectrom; 1999; 13(4):211-5. PubMed ID: 10097399
[TBL] [Abstract][Full Text] [Related]
11. Idoxifene derivatives are less reactive to DNA than tamoxifen derivatives, both chemically and in human and rat liver cells.
Osborne MR; Hewer A; Davis W; Strain AJ; Keogh A; Hardcastle IR; Phillips DH
Carcinogenesis; 1999 Feb; 20(2):293-7. PubMed ID: 10069467
[TBL] [Abstract][Full Text] [Related]
12. DNA adduct formation and mutant induction in Sprague-Dawley rats treated with tamoxifen and its derivatives.
Gamboa da Costa G; McDaniel-Hamilton LP; Heflich RH; Marques MM; Beland FA
Carcinogenesis; 2001 Aug; 22(8):1307-15. PubMed ID: 11470763
[TBL] [Abstract][Full Text] [Related]
13. Minor products of reaction of DNA with alpha-acetoxytamoxifen.
Osborne MR; Hardcastle IR; Phillips DH
Carcinogenesis; 1997 Mar; 18(3):539-43. PubMed ID: 9067554
[TBL] [Abstract][Full Text] [Related]
14. Identification and mechanism of formation of potentially genotoxic metabolites of tamoxifen: study by LC-MS/MS.
Lim CK; Yuan ZX; Jones RM; White IN; Smith LL
J Pharm Biomed Anal; 1997 Jun; 15(9-10):1335-42. PubMed ID: 9226561
[TBL] [Abstract][Full Text] [Related]
15. Identification of hepatic tamoxifen-DNA adducts in mice: alpha-(N(2)-deoxyguanosinyl)tamoxifen and alpha-(N(2)-deoxyguanosinyl)tamoxifen N-oxide.
Umemoto A; Monden Y; Suwa M; Kanno Y; Suzuki M; Lin CX; Ueyama Y; Momen MA; Ravindernath A; Shibutani S; Komaki K
Carcinogenesis; 2000 Sep; 21(9):1737-44. PubMed ID: 10964106
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of tamoxifen and alpha-hydroxytamoxifen 32P-post-labelled DNA adducts by the development of a novel automated on-line solid-phase extraction HPLC method.
Martin EA; Heydon RT; Brown K; Brown JE; Lim CK; White IN; Smith LL
Carcinogenesis; 1998 Jun; 19(6):1061-9. PubMed ID: 9667745
[TBL] [Abstract][Full Text] [Related]
17. DNA adducts formed from 4-hydroxytamoxifen are more mutagenic than those formed by alpha-acetoxytamoxifen in a shuttle vector target gene replicated in human Ad293 cells.
McLuckie KI; Routledge MN; Brown K; Gaskell M; Farmer PB; Roberts GC; Martin EA
Biochemistry; 2002 Jul; 41(28):8899-906. PubMed ID: 12102632
[TBL] [Abstract][Full Text] [Related]
18. Comparison of the DNA adducts formed by tamoxifen and 4-hydroxytamoxifen in vivo.
Beland FA; McDaniel LP; Marques MM
Carcinogenesis; 1999 Mar; 20(3):471-7. PubMed ID: 10190564
[TBL] [Abstract][Full Text] [Related]
19. Induction of tamoxifen-4-hydroxylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), beta-naphthoflavone (beta NF), and phenobarbital (PB) in avian liver: identification of P450 TCDDAA as catalyst of 4-hydroxylation induced by TCDD and beta NF.
Kupfer D; Mani C; Lee CA; Rifkind AB
Cancer Res; 1994 Jun; 54(12):3140-4. PubMed ID: 8205532
[TBL] [Abstract][Full Text] [Related]
20. DNA binding of tamoxifen and its analogues: identification of the tamoxifen-DNA adducts in rat liver.
Rajaniemi H; Koskinen M; Mäntylä E; Hemminki K
Toxicol Lett; 1998 Dec; 102-103():453-7. PubMed ID: 10022295
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
