BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 10208414)

  • 1. p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53.
    Wasylyk C; Salvi R; Argentini M; Dureuil C; Delumeau I; Abecassis J; Debussche L; Wasylyk B
    Oncogene; 1999 Mar; 18(11):1921-34. PubMed ID: 10208414
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adenovirus-mediated E2F-1 gene transfer inhibits MDM2 expression and efficiently induces apoptosis in MDM2-overexpressing tumor cells.
    Yang HL; Dong YB; Elliott MJ; Liu TJ; Atienza C; Stilwell A; McMasters KM
    Clin Cancer Res; 1999 Aug; 5(8):2242-50. PubMed ID: 10473112
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein.
    Martin K; Trouche D; Hagemeier C; Sørensen TS; La Thangue NB; Kouzarides T
    Nature; 1995 Jun; 375(6533):691-4. PubMed ID: 7791903
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The contribution of the RING finger domain of MDM2 to cell cycle progression.
    Argentini M; Barboule N; Wasylyk B
    Oncogene; 2000 Aug; 19(34):3849-57. PubMed ID: 10951578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2.
    Clark PA; Llanos S; Peters G
    Oncogene; 2002 Jul; 21(29):4498-507. PubMed ID: 12085228
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MDM2 and p21WAF1/CIP1, wild-type p53-induced proteins, are regularly expressed by Sternberg-Reed cells in Hodgkin's disease.
    Sánchez-Beato M; Piris MA; Martínez-Montero JC; García JF; Villuendas R; García FJ; Orradre JL; Martínez P
    J Pathol; 1996 Sep; 180(1):58-64. PubMed ID: 8943816
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p21WAF1/CIP1 and MDM2 expression in non-Hodgkin's lymphoma and their relationship to p53 status: a p53+, MDM2-, p21-immunophenotype associated with missense p53 mutations.
    Villuendas R; Pezzella F; Gatter K; Algara P; Sánchez-Beato M; Martínez P; Martínez JC; Muñoz K; García P; Sánchez L; Kocialkowsky S; Campo E; Orradre JL; Piris MA
    J Pathol; 1997 Jan; 181(1):51-61. PubMed ID: 9072003
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction between the retinoblastoma protein and the oncoprotein MDM2.
    Xiao ZX; Chen J; Levine AJ; Modjtahedi N; Xing J; Sellers WR; Livingston DM
    Nature; 1995 Jun; 375(6533):694-8. PubMed ID: 7791904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibiting the p53-MDM2 interaction: an important target for cancer therapy.
    Chène P
    Nat Rev Cancer; 2003 Feb; 3(2):102-9. PubMed ID: 12563309
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines.
    Chène P; Fuchs J; Bohn J; García-Echeverría C; Furet P; Fabbro D
    J Mol Biol; 2000 May; 299(1):245-53. PubMed ID: 10860736
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.
    Midgley CA; Lane DP
    Oncogene; 1997 Sep; 15(10):1179-89. PubMed ID: 9294611
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A nonpeptidic sulfonamide inhibits the p53-mdm2 interaction and activates p53-dependent transcription in mdm2-overexpressing cells.
    Galatin PS; Abraham DJ
    J Med Chem; 2004 Aug; 47(17):4163-5. PubMed ID: 15293988
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.
    Böttger A; Böttger V; Sparks A; Liu WL; Howard SF; Lane DP
    Curr Biol; 1997 Nov; 7(11):860-9. PubMed ID: 9382809
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mdm2 promotes the rapid degradation of p53.
    Haupt Y; Maya R; Kazaz A; Oren M
    Nature; 1997 May; 387(6630):296-9. PubMed ID: 9153395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of p53 stability by Mdm2.
    Kubbutat MH; Jones SN; Vousden KH
    Nature; 1997 May; 387(6630):299-303. PubMed ID: 9153396
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multiple lysine mutations in the C-terminus of p53 make it resistant to degradation mediated by MDM2 but not by human papillomavirus E6 and induce growth inhibition in MDM2-overexpressing cells.
    Nakamura S; Roth JA; Mukhopadhyay T
    Oncogene; 2002 Apr; 21(16):2605-10. PubMed ID: 11971195
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop.
    Arriola EL; Lopez AR; Chresta CM
    Oncogene; 1999 Jan; 18(4):1081-91. PubMed ID: 10023685
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of the p53-MDM2 interaction: targeting a protein-protein interface.
    Chène P
    Mol Cancer Res; 2004 Jan; 2(1):20-8. PubMed ID: 14757842
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fluorescence polarization assay and inhibitor design for MDM2/p53 interaction.
    Zhang R; Mayhood T; Lipari P; Wang Y; Durkin J; Syto R; Gesell J; McNemar C; Windsor W
    Anal Biochem; 2004 Aug; 331(1):138-46. PubMed ID: 15246006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of the degradation function of Mdm2.
    Kubbutat MH; Ludwig RL; Levine AJ; Vousden KH
    Cell Growth Differ; 1999 Feb; 10(2):87-92. PubMed ID: 10074902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.