121 related articles for article (PubMed ID: 10212120)
1. Identification of highly selective inhibitors of collagenase-1 from combinatorial libraries of diketopiperazines.
Szardenings AK; Antonenko V; Campbell DA; DeFrancisco N; Ida S; Shi L; Sharkov N; Tien D; Wang Y; Navre M
J Med Chem; 1999 Apr; 42(8):1348-57. PubMed ID: 10212120
[TBL] [Abstract][Full Text] [Related]
2. Rational design and combinatorial evaluation of enzyme inhibitor scaffolds: identification of novel inhibitors of matrix metalloproteinases.
Szardenings AK; Harris D; Lam S; Shi L; Tien D; Wang Y; Patel DV; Navre M; Campbell DA
J Med Chem; 1998 Jun; 41(13):2194-200. PubMed ID: 9632351
[TBL] [Abstract][Full Text] [Related]
3. Discovery of potent, achiral matrix metalloproteinase inhibitors.
Pikul S; McDow Dunham KL; Almstead NG; De B; Natchus MG; Anastasio MV; McPhail SJ; Snider CE; Taiwo YO; Rydel T; Dunaway CM; Gu F; Mieling GE
J Med Chem; 1998 Sep; 41(19):3568-71. PubMed ID: 9733482
[No Abstract] [Full Text] [Related]
4. Structural basis for the highly selective inhibition of MMP-13.
Engel CK; Pirard B; Schimanski S; Kirsch R; Habermann J; Klingler O; Schlotte V; Weithmann KU; Wendt KU
Chem Biol; 2005 Feb; 12(2):181-9. PubMed ID: 15734645
[TBL] [Abstract][Full Text] [Related]
5. A novel series of highly selective inhibitors of MMP-3.
Whitlock GA; Dack KN; Dickinson RP; Lewis ML
Bioorg Med Chem Lett; 2007 Dec; 17(24):6750-3. PubMed ID: 18029177
[TBL] [Abstract][Full Text] [Related]
6. Identification of potent and selective MMP-13 inhibitors.
Wu J; Rush TS; Hotchandani R; Du X; Geck M; Collins E; Xu ZB; Skotnicki J; Levin JI; Lovering FE
Bioorg Med Chem Lett; 2005 Sep; 15(18):4105-9. PubMed ID: 16005220
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of a small library of diketopiperazines as potential inhibitors of calpain.
Zeng Y; Li Q; Hanzlik RP; Aubé J
Bioorg Med Chem Lett; 2005 Jun; 15(12):3034-8. PubMed ID: 15896956
[TBL] [Abstract][Full Text] [Related]
8. Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1).
Dahlberg L; Billinghurst RC; Manner P; Nelson F; Webb G; Ionescu M; Reiner A; Tanzer M; Zukor D; Chen J; van Wart HE; Poole AR
Arthritis Rheum; 2000 Mar; 43(3):673-82. PubMed ID: 10728762
[TBL] [Abstract][Full Text] [Related]
9. Metabolism of a highly selective gelatinase inhibitor generates active metabolite.
Lee M; Villegas-Estrada A; Celenza G; Boggess B; Toth M; Kreitinger G; Forbes C; Fridman R; Mobashery S; Chang M
Chem Biol Drug Des; 2007 Nov; 70(5):371-82. PubMed ID: 17927722
[TBL] [Abstract][Full Text] [Related]
10. Macrocyclic amino carboxylates as selective MMP-8 inhibitors.
Cherney RJ; Wang L; Meyer DT; Xue CB; Wasserman ZR; Hardman KD; Welch PK; Covington MB; Copeland RA; Arner EC; DeGrado WF; Decicco CP
J Med Chem; 1998 May; 41(11):1749-51. PubMed ID: 9599226
[No Abstract] [Full Text] [Related]
11. Quantitative structure-activity relationship of human neutrophil collagenase (MMP-8) inhibitors using comparative molecular field analysis and X-ray structure analysis.
Matter H; Schwab W; Barbier D; Billen G; Haase B; Neises B; Schudok M; Thorwart W; Schreuder H; Brachvogel V; Lönze P; Weithmann KU
J Med Chem; 1999 Jun; 42(11):1908-20. PubMed ID: 10354399
[TBL] [Abstract][Full Text] [Related]
12. Use of a multiple-enzyme/multiple-reagent assay system to quantify activity levels in samples containing mixtures of matrix metalloproteinases.
Rasmussen FH; Yeung N; Kiefer L; Murphy G; Lopez-Otin C; Vitek MP; Moss ML
Biochemistry; 2004 Mar; 43(11):2987-95. PubMed ID: 15023050
[TBL] [Abstract][Full Text] [Related]
13. QSAR analysis of some 5-amino-2-mercapto-1,3,4-thiadiazole based inhibitors of matrix metalloproteinases and bacterial collagenase.
Jamloki A; Karthikeyan C; Hari Narayana Moorthy NS; Trivedi P
Bioorg Med Chem Lett; 2006 Jul; 16(14):3847-54. PubMed ID: 16682189
[TBL] [Abstract][Full Text] [Related]
14. 3-Hydroxy-4-arylsulfonyltetrahydropyranyl-3-hydroxamic acids are novel inhibitors of MMP-13 and aggrecanase.
Noe MC; Snow SL; Wolf-Gouveia LA; Mitchell PG; Lopresti-Morrow L; Reeves LM; Yocum SA; Liras JL; Vaughn M
Bioorg Med Chem Lett; 2004 Sep; 14(18):4727-30. PubMed ID: 15324896
[TBL] [Abstract][Full Text] [Related]
15. Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13).
Kim SH; Pudzianowski AT; Leavitt KJ; Barbosa J; McDonnell PA; Metzler WJ; Rankin BM; Liu R; Vaccaro W; Pitts W
Bioorg Med Chem Lett; 2005 Feb; 15(4):1101-6. PubMed ID: 15686921
[TBL] [Abstract][Full Text] [Related]
16. Tumor targeting with a selective gelatinase inhibitor.
Koivunen E; Arap W; Valtanen H; Rainisalo A; Medina OP; Heikkilä P; Kantor C; Gahmberg CG; Salo T; Konttinen YT; Sorsa T; Ruoslahti E; Pasqualini R
Nat Biotechnol; 1999 Aug; 17(8):768-74. PubMed ID: 10429241
[TBL] [Abstract][Full Text] [Related]
17. In silico scaffold evaluation and solid phase approach to identify new gelatinase inhibitors.
Topai A; Breccia P; Minissi F; Padova A; Marini S; Cerbara I
Bioorg Med Chem; 2012 Apr; 20(7):2323-37. PubMed ID: 22386984
[TBL] [Abstract][Full Text] [Related]
18. Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: a structure-activity study.
Vassiliou S; Mucha A; Cuniasse P; Georgiadis D; Lucet-Levannier K; Beau F; Kannan R; Murphy G; Knäuper V; Rio MC; Basset P; Yiotakis A; Dive V
J Med Chem; 1999 Jul; 42(14):2610-20. PubMed ID: 10411481
[TBL] [Abstract][Full Text] [Related]
19. Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.
Noe MC; Natarajan V; Snow SL; Wolf-Gouveia LA; Mitchell PG; Lopresti-Morrow L; Reeves LM; Yocum SA; Otterness I; Bliven MA; Carty TJ; Barberia JT; Sweeney FJ; Liras JL; Vaughn M
Bioorg Med Chem Lett; 2005 Jul; 15(14):3385-8. PubMed ID: 15953722
[TBL] [Abstract][Full Text] [Related]
20. Discovery of benzoylpiperazines as a novel class of potent and selective GlyT1 inhibitors.
Pinard E; Alberati D; Borroni E; Fischer H; Hainzl D; Jolidon S; Moreau JL; Narquizian R; Nettekoven M; Norcross RD; Stalder H; Thomas AW
Bioorg Med Chem Lett; 2008 Sep; 18(18):5134-9. PubMed ID: 18752953
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]