147 related articles for article (PubMed ID: 10224072)
1. Multiple activation states of integrin alpha4beta1 detected through their different affinities for a small molecule ligand.
Chen LL; Whitty A; Lobb RR; Adams SP; Pepinsky RB
J Biol Chem; 1999 May; 274(19):13167-75. PubMed ID: 10224072
[TBL] [Abstract][Full Text] [Related]
2. Comparative assessment of the ligand and metal ion binding properties of integrins alpha9beta1 and alpha4beta1.
Pepinsky RB; Mumford RA; Chen LL; Leone D; Amo SE; Riper GV; Whitty A; Dolinski B; Lobb RR; Dean DC; Chang LL; Raab CE; Si Q; Hagmann WK; Lingham RB
Biochemistry; 2002 Jun; 41(22):7125-41. PubMed ID: 12033947
[TBL] [Abstract][Full Text] [Related]
3. Effect of divalent cations on the affinity and selectivity of alpha4 integrins towards the integrin ligands vascular cell adhesion molecule-1 and mucosal addressin cell adhesion molecule-1: Ca2+ activation of integrin alpha4beta1 confers a distinct ligand specificity.
Day ES; Osborn L; Whitty A
Cell Commun Adhes; 2002; 9(4):205-19. PubMed ID: 12699089
[TBL] [Abstract][Full Text] [Related]
4. A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence.
Egger LA; Cao J; McCallum C; Kidambi U; Van Riper G; McCauley E; Mumford RA; Lanza TJ; Lin LS; de Laszlo SE; Young DN; Yang G; Dean DC; Raab CE; Wallace MA; Jones AN; Hagmann WK; Schmidt JA; Pepinsky RB; Scott DM; Lee WC; Cornebise MA; Detmers PA
J Pharmacol Exp Ther; 2003 Sep; 306(3):903-13. PubMed ID: 12766251
[TBL] [Abstract][Full Text] [Related]
5. Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium.
Chen LL; Whitty A; Scott D; Lee WC; Cornebise M; Adams SP; Petter RC; Lobb RR; Pepinsky RB
J Biol Chem; 2001 Sep; 276(39):36520-9. PubMed ID: 11473127
[TBL] [Abstract][Full Text] [Related]
6. Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses.
Lin Kc; Ateeq HS; Hsiung SH; Chong LT; Zimmerman CN; Castro A; Lee WC; Hammond CE; Kalkunte S; Chen LL; Pepinsky RB; Leone DR; Sprague AG; Abraham WM; Gill A; Lobb RR; Adams SP
J Med Chem; 1999 Mar; 42(5):920-34. PubMed ID: 10072689
[TBL] [Abstract][Full Text] [Related]
7. Osteopontin is a ligand for the alpha4beta1 integrin.
Bayless KJ; Meininger GA; Scholtz JM; Davis GE
J Cell Sci; 1998 May; 111 ( Pt 9)():1165-74. PubMed ID: 9547293
[TBL] [Abstract][Full Text] [Related]
8. Fibronectin type III5 repeat contains a novel cell adhesion sequence, KLDAPT, which binds activated alpha4beta1 and alpha4beta7 integrins.
Moyano JV; Carnemolla B; Domínguez-Jiménez C; García-Gila M; Albar JP; Sánchez-Aparicio P; Leprini A; Querzé G; Zardi L; Garcia-Pardo A
J Biol Chem; 1997 Oct; 272(40):24832-6. PubMed ID: 9312081
[TBL] [Abstract][Full Text] [Related]
9. Analysis of ligand-induced and ligand-attenuated epitopes on the leukocyte integrin alpha4beta1: VCAM-1, mucosal addressin cell adhesion molecule-1, and fibronectin induce distinct conformational changes.
Newham P; Craig SE; Clark K; Mould AP; Humphries MJ
J Immunol; 1998 May; 160(9):4508-17. PubMed ID: 9574557
[TBL] [Abstract][Full Text] [Related]
10. Activation status and function of the VLA-4 (alpha4beta1) integrin expressed on human melanoma cell lines.
Saini A; Seller Z; Davies D; Marshall JF; Hart IR
Int J Cancer; 1997 Oct; 73(2):264-70. PubMed ID: 9335453
[TBL] [Abstract][Full Text] [Related]
11. Pulmonary eosinophilia in a murine model of allergic inflammation is attenuated by small molecule alpha4beta1 antagonists.
Kudlacz E; Whitney C; Andresen C; Duplantier A; Beckius G; Chupak L; Klein A; Kraus K; Milici A
J Pharmacol Exp Ther; 2002 May; 301(2):747-52. PubMed ID: 11961081
[TBL] [Abstract][Full Text] [Related]
12. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation.
Chigaev A; Blenc AM; Braaten JV; Kumaraswamy N; Kepley CL; Andrews RP; Oliver JM; Edwards BS; Prossnitz ER; Larson RS; Sklar LA
J Biol Chem; 2001 Dec; 276(52):48670-8. PubMed ID: 11641394
[TBL] [Abstract][Full Text] [Related]
13. Integrin cross talk: activation of lymphocyte function-associated antigen-1 on human T cells alters alpha4beta1- and alpha5beta1-mediated function.
Porter JC; Hogg N
J Cell Biol; 1997 Sep; 138(6):1437-47. PubMed ID: 9298996
[TBL] [Abstract][Full Text] [Related]
14. Dual control by divalent cations and mitogenic cytokines of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity expressed by human hemopoietic cells.
Takamatsu Y; Simmons PJ; Lévesque JP
Cell Adhes Commun; 1998 Jul; 5(5):349-66. PubMed ID: 9789683
[TBL] [Abstract][Full Text] [Related]
15. Identification of potent and novel alpha4beta1 antagonists using in silico screening.
Singh J; Van Vlijmen H; Liao Y; Lee WC; Cornebise M; Harris M; Shu IH; Gill A; Cuervo JH; Abraham WM; Adams SP
J Med Chem; 2002 Jul; 45(14):2988-93. PubMed ID: 12086484
[TBL] [Abstract][Full Text] [Related]
16. Identification of ligand binding sites on integrin alpha4beta1 through chemical cross-linking.
Chen LL; Lobb RR; Cuervo JH; Lin Kc; Adams SP; Pepinsky RB
Biochemistry; 1998 Jun; 37(24):8743-53. PubMed ID: 9628736
[TBL] [Abstract][Full Text] [Related]
17. ADAM disintegrin-like domain recognition by the lymphocyte integrins alpha4beta1 and alpha4beta7.
Bridges LC; Sheppard D; Bowditch RD
Biochem J; 2005 Apr; 387(Pt 1):101-8. PubMed ID: 15504110
[TBL] [Abstract][Full Text] [Related]
18. Alpha4beta1-integrin activation is necessary for high-efficiency T-cell subset interactions with VCAM-1 under flow.
Lim YC; Wakelin MW; Henault L; Goetz DJ; Yednock T; Cabañas C; Sánchez-Madrid F; Lichtman AH; Luscinskas FW
Microcirculation; 2000 Jun; 7(3):201-14. PubMed ID: 10901499
[TBL] [Abstract][Full Text] [Related]
19. Discovery and evaluation of piperidinyl carboxylic acid derivatives as potent alpha(4)beta(1) integrin antagonists.
Müller G; Albers M; Fischer R; Hessler G; Lehmann TE; Okigami H; Tajimi M; Bacon K; Rölle T
Bioorg Med Chem Lett; 2001 Dec; 11(23):3019-21. PubMed ID: 11714601
[TBL] [Abstract][Full Text] [Related]
20. The Src kinase p56(lck) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin.
Feigelson SW; Grabovsky V; Winter E; Chen LL; Pepinsky RB; Yednock T; Yablonski D; Lobb R; Alon R
J Biol Chem; 2001 Apr; 276(17):13891-901. PubMed ID: 11102438
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]