BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 10227700)

  • 1. Grapefruit juice activates P-glycoprotein-mediated drug transport.
    Soldner A; Christians U; Susanto M; Wacher VJ; Silverman JA; Benet LZ
    Pharm Res; 1999 Apr; 16(4):478-85. PubMed ID: 10227700
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells.
    Takanaga H; Ohnishi A; Matsuo H; Sawada Y
    Biol Pharm Bull; 1998 Oct; 21(10):1062-6. PubMed ID: 9821810
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
    Kim RB; Wandel C; Leake B; Cvetkovic M; Fromm MF; Dempsey PJ; Roden MM; Belas F; Chaudhary AK; Roden DM; Wood AJ; Wilkinson GR
    Pharm Res; 1999 Mar; 16(3):408-14. PubMed ID: 10213372
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein.
    Di Marco MP; Edwards DJ; Wainer IW; Ducharme MP
    Life Sci; 2002 Jul; 71(10):1149-60. PubMed ID: 12095536
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
    Raeissi SD; Hidalgo IJ; Segura-Aguilar J; Artursson P
    Pharm Res; 1999 May; 16(5):625-32. PubMed ID: 10350002
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.
    Lown KS; Bailey DG; Fontana RJ; Janardan SK; Adair CH; Fortlage LA; Brown MB; Guo W; Watkins PB
    J Clin Invest; 1997 May; 99(10):2545-53. PubMed ID: 9153299
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of human CYP3A and P-glycoprotein on the absorption of drugs.
    van de Waterbeemd H
    Eur J Pharm Sci; 2000 Nov; 12(1):1. PubMed ID: 11121728
    [No Abstract]   [Full Text] [Related]  

  • 8. Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components.
    Eagling VA; Profit L; Back DJ
    Br J Clin Pharmacol; 1999 Oct; 48(4):543-52. PubMed ID: 10583025
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
    Hendrikx JJ; Lagas JS; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
    Int J Cancer; 2013 May; 132(10):2439-47. PubMed ID: 23090875
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine.
    Suzuki H; Sugiyama Y
    Eur J Pharm Sci; 2000 Nov; 12(1):3-12. PubMed ID: 11121729
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of human P-glycoprotein in Caco-2 cells: development of a highly sensitive assay system for P-glycoprotein-mediated drug transport.
    Shirasaka Y; Kawasaki M; Sakane T; Omatsu H; Moriya Y; Nakamura T; Sakaeda T; Okumura K; Langguth P; Yamashita S
    Drug Metab Pharmacokinet; 2006 Oct; 21(5):414-23. PubMed ID: 17072095
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.
    Ohnishi A; Matsuo H; Yamada S; Takanaga H; Morimoto S; Shoyama Y; Ohtani H; Sawada Y
    Br J Pharmacol; 2000 Jul; 130(6):1369-77. PubMed ID: 10903978
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 6',7'-Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein.
    Edwards DJ; Fitzsimmons ME; Schuetz EG; Yasuda K; Ducharme MP; Warbasse LH; Woster PM; Schuetz JD; Watkins P
    Clin Pharmacol Ther; 1999 Mar; 65(3):237-44. PubMed ID: 10096255
    [TBL] [Abstract][Full Text] [Related]  

  • 14. P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies.
    Wandel C; Kim RB; Kajiji S; Guengerich P; Wilkinson GR; Wood AJ
    Cancer Res; 1999 Aug; 59(16):3944-8. PubMed ID: 10463589
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4.
    Takanaga H; Ohnishi A; Yamada S; Matsuo H; Morimoto S; Shoyama Y; Ohtani H; Sawada Y
    J Pharmacol Exp Ther; 2000 Apr; 293(1):230-6. PubMed ID: 10734174
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.
    Cummins CL; Jacobsen W; Benet LZ
    J Pharmacol Exp Ther; 2002 Mar; 300(3):1036-45. PubMed ID: 11861813
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.
    Honda Y; Ushigome F; Koyabu N; Morimoto S; Shoyama Y; Uchiumi T; Kuwano M; Ohtani H; Sawada Y
    Br J Pharmacol; 2004 Dec; 143(7):856-64. PubMed ID: 15504753
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro.
    Wandel C; Kim RB; Guengerich FP; Wood AJ
    Drug Metab Dispos; 2000 Aug; 28(8):895-8. PubMed ID: 10901697
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mdr1 limits CYP3A metabolism in vivo.
    Lan LB; Dalton JT; Schuetz EG
    Mol Pharmacol; 2000 Oct; 58(4):863-9. PubMed ID: 10999959
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein.
    Zhang Y; Benet LZ
    Clin Pharmacokinet; 2001; 40(3):159-68. PubMed ID: 11327196
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.