218 related articles for article (PubMed ID: 10229234)
1. Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.
Chui DH; Tanahashi H; Ozawa K; Ikeda S; Checler F; Ueda O; Suzuki H; Araki W; Inoue H; Shirotani K; Takahashi K; Gallyas F; Tabira T
Nat Med; 1999 May; 5(5):560-4. PubMed ID: 10229234
[TBL] [Abstract][Full Text] [Related]
2. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
Jaffar S; Counts SE; Ma SY; Dadko E; Gordon MN; Morgan D; Mufson EJ
Exp Neurol; 2001 Aug; 170(2):227-43. PubMed ID: 11476589
[TBL] [Abstract][Full Text] [Related]
3. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
Mohmmad Abdul H; Sultana R; Keller JN; St Clair DK; Markesbery WR; Butterfield DA
J Neurochem; 2006 Mar; 96(5):1322-35. PubMed ID: 16478525
[TBL] [Abstract][Full Text] [Related]
4. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.
Duff K; Eckman C; Zehr C; Yu X; Prada CM; Perez-tur J; Hutton M; Buee L; Harigaya Y; Yager D; Morgan D; Gordon MN; Holcomb L; Refolo L; Zenk B; Hardy J; Younkin S
Nature; 1996 Oct; 383(6602):710-3. PubMed ID: 8878479
[TBL] [Abstract][Full Text] [Related]
5. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
Kurt MA; Davies DC; Kidd M; Duff K; Rolph SC; Jennings KH; Howlett DR
Exp Neurol; 2001 Sep; 171(1):59-71. PubMed ID: 11520121
[TBL] [Abstract][Full Text] [Related]
6. Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer's disease.
Page G; Rioux Bilan A; Ingrand S; Lafay-Chebassier C; Pain S; Perault Pochat MC; Bouras C; Bayer T; Hugon J
Neuroscience; 2006; 139(4):1343-54. PubMed ID: 16581193
[TBL] [Abstract][Full Text] [Related]
7. Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.
Zhang Z; Hartmann H; Do VM; Abramowski D; Sturchler-Pierrat C; Staufenbiel M; Sommer B; van de Wetering M; Clevers H; Saftig P; De Strooper B; He X; Yankner BA
Nature; 1998 Oct; 395(6703):698-702. PubMed ID: 9790190
[TBL] [Abstract][Full Text] [Related]
8. Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice.
Hartmann J; Erb C; Ebert U; Baumann KH; Popp A; König G; Klein J
Neuroscience; 2004; 125(4):1009-17. PubMed ID: 15120860
[TBL] [Abstract][Full Text] [Related]
9. [Significance of intracellular A beta in Alzheimer's disease].
Tabira T
Nihon Shinkei Seishin Yakurigaku Zasshi; 2002 Oct; 22(5):175-80. PubMed ID: 12451689
[TBL] [Abstract][Full Text] [Related]
10. Neuropathological characterization of mutant amyloid precursor protein yeast artificial chromosome transgenic mice.
Kulnane LS; Lamb BT
Neurobiol Dis; 2001 Dec; 8(6):982-92. PubMed ID: 11741394
[TBL] [Abstract][Full Text] [Related]
11. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
Wen PH; Hof PR; Chen X; Gluck K; Austin G; Younkin SG; Younkin LH; DeGasperi R; Gama Sosa MA; Robakis NK; Haroutunian V; Elder GA
Exp Neurol; 2004 Aug; 188(2):224-37. PubMed ID: 15246822
[TBL] [Abstract][Full Text] [Related]
12. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
Terro F; Czech C; Esclaire F; Elyaman W; Yardin C; Baclet MC; Touchet N; Tremp G; Pradier L; Hugon J
J Neurosci Res; 2002 Aug; 69(4):530-9. PubMed ID: 12210846
[TBL] [Abstract][Full Text] [Related]
13. Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice.
Wen PH; Shao X; Shao Z; Hof PR; Wisniewski T; Kelley K; Friedrich VL; Ho L; Pasinetti GM; Shioi J; Robakis NK; Elder GA
Neurobiol Dis; 2002 Jun; 10(1):8-19. PubMed ID: 12079399
[TBL] [Abstract][Full Text] [Related]
14. Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse.
Gordon MN; Holcomb LA; Jantzen PT; DiCarlo G; Wilcock D; Boyett KW; Connor K; Melachrino J; O'Callaghan JP; Morgan D
Exp Neurol; 2002 Feb; 173(2):183-95. PubMed ID: 11822882
[TBL] [Abstract][Full Text] [Related]
15. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease.
Simard AR; Soulet D; Gowing G; Julien JP; Rivest S
Neuron; 2006 Feb; 49(4):489-502. PubMed ID: 16476660
[TBL] [Abstract][Full Text] [Related]
16. Estrogen treatment improves spatial learning in APP + PS1 mice but does not affect beta amyloid accumulation and plaque formation.
Heikkinen T; Kalesnykas G; Rissanen A; Tapiola T; Iivonen S; Wang J; Chaudhuri J; Tanila H; Miettinen R; Puoliväli J
Exp Neurol; 2004 May; 187(1):105-17. PubMed ID: 15081593
[TBL] [Abstract][Full Text] [Related]
17. Enhanced accumulation of tau in doubly transgenic mice expressing mutant betaAPP and presenilin-1.
Samura E; Shoji M; Kawarabayashi T; Sasaki A; Matsubara E; Murakami T; Wuhua X; Tamura S; Ikeda M; Ishiguro K; Saido TC; Westaway D; St George Hyslop P; Harigaya Y; Abe K
Brain Res; 2006 Jun; 1094(1):192-9. PubMed ID: 16713590
[TBL] [Abstract][Full Text] [Related]
18. Transient intraneuronal A beta rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice.
Christensen DZ; Kraus SL; Flohr A; Cotel MC; Wirths O; Bayer TA
Acta Neuropathol; 2008 Dec; 116(6):647-55. PubMed ID: 18974993
[TBL] [Abstract][Full Text] [Related]
19. Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.
Poduslo JF; Curran GL; Wengenack TM; Malester B; Duff K
Neurobiol Dis; 2001 Aug; 8(4):555-67. PubMed ID: 11493021
[TBL] [Abstract][Full Text] [Related]
20. Presenilin mutations in Alzheimer's disease.
Cruts M; Van Broeckhoven C
Hum Mutat; 1998; 11(3):183-90. PubMed ID: 9521418
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
